Patents by Inventor María Isabel Lema Gesto

María Isabel Lema Gesto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for Diagnosis and Prognosis of Corneal Ectatic Disorders
    Publication number: 20210132084
    Abstract: The invention relates to the field of the diagnosis and prognosis methods of molecular pathologies. In particular, the invention relates to methods for determining the diagnosis of an ectatic disease of the cornea in a subject, for determining the risk of developing an ectatic disease of the cornea in a subject, for determining the clinical outcome of a subject suffering from an ectatic disease of the cornea and for selecting a subject to be treated with a therapy for an ectatic disease of the cornea based on the determination of the expression levels of TLR2 and/or TLR4 markers. The invention also relates to the use of the TLR2 and/or TLR4 as diagnosis and prognosis markers for an ectatic disease of the cornea.
    Type: Application
    Filed: January 11, 2021
    Publication date: May 6, 2021
    Inventors: Maria Isabel Lema Gesto, José Antonio Castillo Sánchez, Tomás Sobrino Moreiras, Francisco Campos Perez
  • Biomarkers for diagnosis and prognosis of corneal ectatic disorders
    Patent number: 10914746
    Abstract: The invention relates to the field of the diagnosis and prognosis methods of molecular pathologies. In particular, the invention relates to methods for determining the diagnosis of an ectatic disease of the cornea in a subject, for determining the risk of developing an ectatic disease of the cornea in a subject, for determining the clinical outcome of a subject suffering from an ectatic disease of the cornea and for selecting a subject to be treated with a therapy for an ectatic disease of the cornea based on the determination of the expression levels of TLR2 and/or TLR4 markers. The invention also relates to the use of the TLR2 and/or TLR4 as diagnosis and prognosis markers for an ectatic disease of the cornea.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: February 9, 2021
    Assignees: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, SERVIZO GALEGO DE SAUDE (SERGAS)
    Inventors: María Isabel Lema Gesto, José Antonio Castillo Sánchez, Tomás Sobrino Moreiras, Francisco Campos Perez
  • BIOMARKERS FOR DIAGNOSIS AND PROGNOSIS OF CORNEAL ECTATIC DISORDERS
    Publication number: 20180067128
    Abstract: The invention relates to the field of the diagnosis and prognosis methods of molecular pathologies. In particular, the invention relates to methods for determining the diagnosis of an ectatic disease of the cornea in a subject, for determining the risk of developing an ectatic disease of the cornea in a subject, for determining the clinical outcome of a subject suffering from an ectatic disease of the cornea and for selecting a subject to be treated with a therapy for an ectatic disease of the cornea based on the determination of the expression levels of TLR2 and/or TLR4 markers. The invention also relates to the use of the TLR2 and/or TLR4 as diagnosis and prognosis markers for an ectatic disease of the cornea.
    Type: Application
    Filed: February 16, 2016
    Publication date: March 8, 2018
    Inventors: María Isabel Lema Gesto, José Antonio Castillo Sánchez, Tomás Sobrino Moreiras, Francisco Campos Perez