Patents by Inventor Mara N. GLADSTONE

Mara N. GLADSTONE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bouvardin derivatives and therapeutic uses thereof
    Patent number: 10259846
    Abstract: The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: April 16, 2019
    Assignees: The Regents of the University of Colorado, Suvica, Inc.
    Inventors: Tin Tin Su, Mara N. Gladstone, Gan Zhang, Tarek Sammakia
  • BOUVARDIN DERIVATIVES AND THERAPEUTIC USES THEREOF
    Publication number: 20170218025
    Abstract: The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 3, 2017
    Inventors: Tin Tin SU, Mara N. GLADSTONE, Gan ZHANG, Tarek SAMMAKIA
  • Bourvadin derivatives and therapeutic uses thereof
    Patent number: 9452215
    Abstract: The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: September 27, 2016
    Assignees: THE REGENTS OF THE UNIVERSITY OF COLORADO, SUVICA, INC.
    Inventors: Tin Tin Su, Mara N. Gladstone, Gan Zhang, Tarek Sammakia
  • BOURVADIN DERIVATIVES AND THERAPEUTIC USES THEREOF
    Publication number: 20150238562
    Abstract: The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
    Type: Application
    Filed: February 21, 2013
    Publication date: August 27, 2015
    Inventors: Tin Tin SU, Mara N. GLADSTONE, Gan ZHANG, Tarek SAMMAKIA