Patents by Inventor Mara Pavel-Dinu

Mara Pavel-Dinu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE CORRECTION FOR RAG2 DEFICIENCY IN HUMAN STEM CELLS
    Publication number: 20240173355
    Abstract: The present disclosure provides methods and compositions for treating RAG2 deficiencies in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating a functional, codon-optimized RAG 2 cDNA at the endogenous RAG2 locus.
    Type: Application
    Filed: April 5, 2022
    Publication date: May 30, 2024
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mara Pavel-Dinu, Matthew H. Porteus
  • GENE CORRECTION FOR SCID-X1 IN LONG-TERM HEMATOPOIETIC STEM CELLS
    Publication number: 20240093242
    Abstract: The present disclosure provides methods and compositions for treating SCID-X1 in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating a full-length, codon-optimized IL2RG cDNA at the endogenous IL2RG locus.
    Type: Application
    Filed: August 3, 2021
    Publication date: March 21, 2024
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mara Pavel-Dinu, Matthew H. Porteus
  • GENE CORRECTION FOR X-CGD IN HEMATOPOIETIC STEM AND PROGENITOR CELLS
    Publication number: 20230357798
    Abstract: The present disclosure provides methods and compositions for treating X-CGD in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating a functional, codon-optimized CYBB cDNA at the endogenous CYBB locus.
    Type: Application
    Filed: October 12, 2021
    Publication date: November 9, 2023
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mara Pavel-Dinu, Matthew H. Porteus