Patents by Inventor Maram K. Reddy

Maram K. Reddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide synthase nanoparticles for treatment of vascular disease
    Patent number: 10016488
    Abstract: A sustained-release composition for stimulating endothelial cell growth including a nitric oxide synthase within a nanoparticle comprising a biocompatible polymer is described. The sustained-release composition can be administered as part of a pharmaceutical composition, or can be coated on a medical device. The nitric oxide synthase-containing nanoparticles can be used in a method of inducing endothelium formation in a blood vessel.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: July 10, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vinod Labhasetwar, Jaspreet K. Vasir, Maram K. Reddy
  • SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS FOR USING THE SAME
    Publication number: 20170000742
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Application
    Filed: July 21, 2016
    Publication date: January 5, 2017
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • NITRIC OXIDE SYNTHASE NANOPARTICLES FOR TREATMENT OF VASCULAR DISEASE
    Publication number: 20160324935
    Abstract: A sustained-release composition for stimulating endothelial cell growth including a nitric oxide synthase within a nanoparticle comprising a biocompatible polymer is described. The sustained-release composition can be administered as part of a pharmaceutical composition, or can be coated on a medical device. The nitric oxide synthase-containing nanoparticles can be used in a method of inducing endothelium formation in a blood vessel.
    Type: Application
    Filed: April 13, 2016
    Publication date: November 10, 2016
    Inventors: Vinod Labhasetwar, Jaspreet K. Vasir, Maram K. Reddy
  • SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS FOR USING THE SAME
    Publication number: 20160030402
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Application
    Filed: September 21, 2015
    Publication date: February 4, 2016
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • Sustained-release nanoparticle compositions and methods using the same
    Patent number: 9138416
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: September 22, 2015
    Assignee: Board of Regents of the University of Nebraska by and behalf of the University of Nebraska Medical Center
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS USING THE SAME
    Publication number: 20140050798
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Application
    Filed: October 28, 2013
    Publication date: February 20, 2014
    Applicant: Board of Regents of the Univ. of Nebraska by and Behalf of the University of Nebraska Medical Cente
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • Method for inhibiting reperfusion injury in the brain
    Patent number: 8182807
    Abstract: The present invention relates to a method for inhibiting reperfusion injury in the brain. The method involve injecting via the carotid artery or jugular vein an antioxidant-loaded nanoparticle. A nanoparticle formulation containing an inert plasticizer is also provided for sustained release of an active agent.
    Type: Grant
    Filed: February 19, 2008
    Date of Patent: May 22, 2012
    Assignee: Board of Regents of the University of Nebraska by and on Behalf of the University of Nebraska Medical Center
    Inventors: Vinod D. Labhasetwar, Maram K. Reddy
  • SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS USING THE SAME
    Publication number: 20100203153
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Application
    Filed: April 19, 2010
    Publication date: August 12, 2010
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • Sustained-release nanoparticle compositions and methods for using the same
    Patent number: 7727554
    Abstract: The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: June 1, 2010
    Assignee: Board of Regents of the University of Nebraska by and Behalf of the University of Nebraska Medical Center
    Inventors: Vinod D. Labhasetwar, Sanjeeb K. Sahoo, Maram K. Reddy
  • METHOD AND COMPOSITION FOR INHIBITING REPERFUSION INJURY IN THE BRAIN
    Publication number: 20080248118
    Abstract: The present invention relates to a method for inhibiting reperfusion injury in the brain. The method involve injecting via the carotid artery or jugular vein an antioxidant-loaded nanoparticle. A nanoparticle formulation containing an inert plasticizer is also provided for sustained release of an active agent.
    Type: Application
    Filed: February 19, 2008
    Publication date: October 9, 2008
    Inventors: Vinod D. Labhasetwar, Maram K. Reddy
  • Method and composition for inhibiting reperfusion injury in the brain
    Patent number: 7332159
    Abstract: The present invention relates to a method for inhibiting reperfusion injury in the brain. The method involve injecting via the carotid artery or jugular vein an antioxidant-loaded nanoparticle. A nanoparticle formulation containing an inert plasticizer is also provided for sustained release of an active agent.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: February 19, 2008
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Vinod D. Labhasetwar, Maram K. Reddy