Abstract: Provided are TCRs (e.g., TCRs that bind to NY-ESO-1), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.

Abstract: A camera monitors positions on an external object having a beacon (1(i), i=1, 2, . . . , I; 130; 430) attached to it. The apparatus has at least one image sensor (120; 321, 322; 420; 520), an imaging optical element (101) for projecting light on the image sensor (120), and a processing unit (9). The imaging optical element (101) may be non-refractive and receives a light beam (5(i); 131) transmitted from the beacon (1(i); 130; 430) and transfers the light beam (5(i); 131) to the image sensor (120; 321, 322; 420; 520). The image sensor (120; 321, 322; 420; 520) forms image data based on the received light beam (5(i); 131) and background light. The processing unit (9) processes the image data such that it filters image data components relating to the background light and renders image data components relating to the light beam.

Abstract: A universal interface adapter circuit interfaces, for example, a wireless communications headset with any type of communications system, including those that require push-to-talk (PTT) signaling. The interface adapter is comprised of several main components, including an RF signaling receiver, a microcontroller and associated circuitry for decoding and processing the received signals, and programmable impedance matching and line interfacing circuitry for interfacing a wireless communications headset system base to a communications system. A signaling transmitter, which is preferably portable (e.g., handheld), is employed by the wireless headset user to send signals to the signaling receiver. In an embodiment of the invention directed specifically to push-to-talk (PTT) signaling, the wireless headset user presses a button on the signaling transmitter when they wish to speak. This sends a signal to the microcontroller which decodes the signal and recognizes the signal as being a PTT request.