Patents by Inventor Marc Andre Bailly

Marc Andre Bailly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARGINASE 1 BINDERS FOR INHIBITING ARGINASE 1 ACTIVITY
    Publication number: 20240002533
    Abstract: Arginase 1 binders comprising human antibodies and antigen-binding fragments thereof that inhibit the activity of human Arginase 1 (hArg1) are described. These Arginase 1 binders present an alternative mechanism for inhibiting hArg1 activity and highlight the ability to utilize binders as probes in the discovery and development of peptide and small molecule inhibitors for enzymes in general.
    Type: Application
    Filed: November 22, 2021
    Publication date: January 4, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Marc Andre Bailly, Kalyan Chakravarthy, Ghassan Najib Fayad, Laurence Fayadat-Dilman, Veronica Juan, Esther Kofman, Heping Lin, Jennifer E. O'Neil, Rachel Lynn Palte, Giovanna Scapin, Hussam Hisham Shaheen, Tao Wang
  • ARGINASE 1 BINDERS FOR INHIBITING ARGINASE 1 ACTIVITY
    Publication number: 20240002535
    Abstract: Arginase 1 binders that inhibit activity of hArg1, which comprise humanized anti-human Arginase 1 (hArg1) antibodies and antigen-binding fragments thereof obtained from mouse monoclonal antibodies comprising mouse VH and VL, are described. These Arginase 1 binders present an alternative mechanism for inhibiting hArg1 activity and highlight the ability to utilize binders as probes in the discovery and development of peptide and small molecule inhibitors for enzymes in general.
    Type: Application
    Filed: November 22, 2021
    Publication date: January 4, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Marc Andre Bailly, Kalyan Chakravarthy, Ghassan Najib Fayad, Laurence Fayadat-Dilman, Veronica Juan, Esther Kofman, Masahisa Handa, Jennifer E. O'Neil, Rachel Lynn Palte, Giovanna Scapin, Shahriar Shane Taremi
  • ARGINASE 1 BINDERS FOR INHIBITING ARGINASE 1 ACTIVITY
    Publication number: 20240002534
    Abstract: Arginase 1 binders that inhibit the activity of human Arginase 1 (hArg1) and comprise human antibodies and antigen-binding fragments thereof comprising human VH and VL are described. These Arginase 1 binders present an alternative mechanism for inhibiting hArg1 activity and highlight the ability to utilize binders as probes in the discovery and development of peptide and small molecule inhibitors for enzymes in general.
    Type: Application
    Filed: November 22, 2021
    Publication date: January 4, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Marc Andre Bailly, Kalyan Chakravarthy, Ghassan Najib Fayad, Laurence Fayadat-Dilman, Esther Kofman, Masahisa Handa, Jennifer E. O'Neil, Rachel Lynn Palte, Giovanna Scapin, Shahriar Shane Taremi