Abstract: Arginase 1 binders comprising human antibodies and antigen-binding fragments thereof that inhibit the activity of human Arginase 1 (hArg1) are described. These Arginase 1 binders present an alternative mechanism for inhibiting hArg1 activity and highlight the ability to utilize binders as probes in the discovery and development of peptide and small molecule inhibitors for enzymes in general.

Abstract: Arginase 1 binders that inhibit the activity of human Arginase 1 (hArg1) and comprise human antibodies and antigen-binding fragments thereof comprising human VH and VL are described. These Arginase 1 binders present an alternative mechanism for inhibiting hArg1 activity and highlight the ability to utilize binders as probes in the discovery and development of peptide and small molecule inhibitors for enzymes in general.

Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.

Abstract: A method of preparing an alkoxy-functional organosilicon compound is provided. The method comprises reacting (A) an initial organosilicon compound and (B) an alcohol component in the presence of (C) a catalyst, thereby preparing the alkoxy-functional organosilicon compound. The initial organosilicon compound (A) comprises at least one alkoxysilyl group. The alcohol component (B) comprises an organic alcohol. The catalyst (C) comprises (C1) an ammonium carboxylate compound or (C2) a titanate compound. A reaction product comprising an alkoxy-functional organosilicon compound prepared in accordance with the method, and a composition comprising the reaction product, are also provided. The alkoxy-functional organosilicon compound, and the reaction product and composition comprising the same, are prepared in increased purity under functional group-tolerant conditions.

Abstract: A method (100) of automated identification of one or more malfunction areas of a set (S) of malfunction areas for a service case in which a medical device (12) is serviced includes: generating an output probability vector (40) of probabilities for the set of malfunction areas of the medical device by operations including applying at least one classifier (42, 46) to at least one of (1) text descriptions of parts ordered for the service case and/or (2) a text description of the service case; and displaying a list (56) of one or more most probable malfunction areas for the service case wherein the one or more most probable malfunction areas are the one or more most malfunction areas of the set of malfunction areas having highest probability in the output probability vector.

Abstract: The present invention relates to a new dehydrogenation process of specific compounds.

Abstract: Processes for synthesizing new compounds that may usefully be employed in organic synthesis, especially in the synthesis of vitamin A or ?-carotene and derivatives thereof, e.g. canthaxanthin, astaxanthin or zeaxanthin are disclosed. The new compounds are especially useful as intermediates (building blocks) in the synthesis of vitamin A or ?-carotene, preferably vitamin A.

Abstract: An earpiece (100) and acoustic management module (300) for in-ear canal echo suppression control suitable is provided. The earpiece can include an Ambient Sound Microphone (111) to capture ambient sound, an Ear Canal Receiver (125) to deliver audio content to an ear canal, an Ear Canal Microphone (123) configured to capture internal sound, and a processor (121) to generate a voice activity level (622) and suppress an echo of spoken voice in the electronic internal signal, and mix an electronic ambient signal with an electronic internal signal in a ratio dependent on the voice activity level and a background noise level to produce a mixed signal (323) that is delivered to the ear canal (131).

Abstract: A method (100) of generating a ranked list (42) of alerts (30) from files (32) of electronic devices (12) includes: applying predictive models (34) to data of the files to generate maintenance alerts for the electronic devices; assigning discrete values for a set of criteria (36) to each maintenance alert whereby the maintenance alert has a share computed as a product of the assigned discrete values; performing a credit-based queuing process (38) to assign the maintenance alerts to slots of a ranked list, wherein in the credit-based queuing process the maintenance alerts accumulate credits in accord with the shares computed for the respective maintenance alerts; and displaying, on a display device (24) operatively connected with the at least one electronic processor, the maintenance alerts as the ranked list in accordance with the assignments of the maintenance alerts to the slots of the ranked list.

Abstract: A silicon glycan is provided. The silicon glycan comprises a glycoside moiety, independently selected organosilicon moieties, and beta-amino alcohol moieties joining the organosilicon moieties to the glycoside moiety. The glycoside moiety comprises independently selected saccharide moieties, which may be substituted with hydrocarbyl groups, ether moieties, and/or amine moieties. A method of preparing the silicon glycan is also provided. The method includes reacting (A) an aminoethyl polysaccharide and (B) an epoxide-functional organosilicon compound, to give the silicon glycan. The method may include preparing the aminoethyl polysaccharide (A) by first reacting (At) a hydroxyl-functional polysaccharide and (A2) an aziridinium halide compound to give the aminoethyl polysaccharide (A).

Abstract: A vacuum bag system (VBS) for forming pre-consolidated composite blanks has a blank enclosure for sealing around a periphery of the blank, while leaving a second side of the blank exposed, an articulated forming caul (AFC) with at least two facets, each facet effectively jointedly coupled to an adjacent facet, and having a respective, independently controlled, heater integrated with, or coupled to the facet. The VBS further has a forming enclosure for sealing around a periphery of a tool. The blank enclosure brings the blank and the facets into uniform thermal contact resistance and mechanical contact; and permits the articulated AFC to distribute thermal and mechanical load across the blank during forming, even as the facets move to align to faces of the mold.

Abstract: Methods and systems of operating a gas turbine engine in a low-power condition are provided. In one embodiment, the method includes supplying fuel to the combustor by supplying fuel to the first fuel manifold via a first flow divider valve and supplying fuel to the second fuel manifold via a second flow divider valve. While supplying fuel to the combustor by supplying fuel to the first fuel manifold, the method includes stopping supplying fuel to the second fuel manifold and supplying pressurized gas to the second fuel manifold via the second flow divider valve to flush fuel in the second fuel manifold into the combustor and hinder coking in the second fuel manifold and associated nozzles.

Abstract: A non-transitory computer readable medium (26) stores instructions executable by at least one electronic processor (20) to perform a method (100) of detecting issues with wireless connections. The method includes: receiving Wi-Fi roaming data for wireless devices (12) connected to a wireless electronic data communication network (14) comprising a plurality of access points (APs) (16) dispersed through a facility; from the received Wi-Fi roaming data, determining single-AP disconnect events for the APs wherein a single-AP disconnect event for an AP comprises a disconnection of the AP from a wireless device followed by a reconnection of the AP with the wireless device without the wireless device connecting to any other AP during a time interval between the disconnection and the reconnection; and generating an alert (30) for any AP whose rate of single-AP disconnect events exceeds a predetermined single-AP disconnect rate alert threshold.

Abstract: The present disclosure provides a system, apparatus and method for providing rapid shutdown for photovoltaic power systems and provides a system, apparatus and method for providing arc sensing for photovoltaic power systems. An AC current can be put on the DC bus to control PV panel shutdown. Local mean decomposition can be used to sense arcing on the DC bus.

Abstract: In example embodiments, techniques are provided for efficiently labeling, reviewing and correcting predictions for P&IDs in image-only formats. To label text boxes in the P&ID, the labeling application executes an OCR algorithm to predict a bounding box around, and machine-readable text within, each text box, and displays these predictions in its user interface. The labeling application provides functionality to receive a user confirmation or correction for each predicted bounding box and predicted machine-readable text. To label symbols in the P&ID, the labeling application receives user input to draw bounding boxes around symbols and assign symbols to classes of equipment. Where there are multiple occurrences of specific symbols, the labeling application provides functionality to duplicate and automatically detect and assign bounding boxes and classes.

Abstract: An exhaust-gas guiding housing for an exhaust-gas system of an internal combustion engine includes an air inlet housing part through which exhaust gas can flow in an exhaust-gas main flow direction and which has a housing wall surrounding a housing longitudinal axis. At least one air inlet opening is provided in at least one air inlet peripheral region of the housing wall. An inner wall is provided at an inner side of the air inlet housing part, which inner wall, together with the housing wall, defines an air inlet chamber. The at least one air inlet opening is open to the air inlet chamber. At least one air passage opening is provided in the inner wall, and/or at least one air passage opening is formed between the inner wall and the housing wall.

Abstract: Methods of preparing plant-derived proteins or suprastructure proteins, are provided. The method may comprise obtaining a plant, or plant matter comprising apoplast-localized proteins, or suprastructure proteins, producing a protoplast/spheroplast fraction and apoplast fraction from the plant or plant matter, and recovering the apoplast fraction. The apoplast fraction comprises plant-derived proteins or suprastructure proteins. Alternatively, the proteins, or suprastructure proteins, may be obtained from plant or plant matter comprising plant-derived proteins or suprastructure proteins, by digesting the plant matter using a cell wall degrading enzyme composition to produced a digested fraction. The digested fraction is filtered to produced a filtered fraction, and the plant-derived proteins or suprastructure proteins, are recovered from the filtered fraction.

Abstract: A decoder receives a compressed red green blue depth, RGBD, frame of a video. The decoder accesses a reference RGBD frame. The decoder reprojects the reference RGBD frame using a depth channel of the reference RGBD frame and a camera pose, to compute a reprojected version of the reference frame. The decoder uses the reprojected version of the reference frame to decode the compressed RGBD frame.

Abstract: The present disclosure relates to techniques for presenting a combined view of a virtual environment and a real environment in response to detecting a transition event associated with an object in the real environment. While presenting the combined view, if an input of a first type is detected, the combined view is adjusted by increasing the visibility of imagery of the virtual environment and decreasing the visibility of imagery of the real environment. If an input of a second type is detected, the combined view is adjusted by decreasing the visibility of the imagery of the virtual environment and increasing the visibility of the imagery of the real environment.

Abstract: A device for providing reference information in laser speckle medical imaging of tissue of a subject can include a support that includes a marker for image recognition and a speckle target region that is nontransparent to light in a first illumination wavelength range and that generates a speckle pattern when illuminated with light in the first wavelength range. The support can be configured to be attachable to tissue of the subject.