Abstract: A pre-filled medical delivery assembly comprising a blow-fill-seal (BFS) bottle with a collapsible reservoir, a neck portion, and a side flange, an administration assembly comprising a collar with a mounting socket with an interior seat into which the neck portion is axially inserted, a needle hub coupled to a double-ended needle comprising a piercing end within the mounting socket and an administration end. A needle shield covers the needle after use and includes a shield base, a shield element, and a hinge flexibly connecting the shield base and the shield. The shield base further comprises at least one circumferential notch that couples to at least one side flange of the BFS bottle.

Abstract: A fluid delivery manifold system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular manifold design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular manifold construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery manifold configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery).

Abstract: A pre-filled blow-fill-seal (BFS) IntraDermal (ID) medical agent injection system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a BFS vial to a patient in an auto-disable fashion.

Abstract: The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient.

Abstract: The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient.

Abstract: A pre-filled blow-fill-seal (BFS) vial can have a fluid seal at one end thereof that can be breached by a piercing element within a connector when a neck of the BFS vial is fully inserted into the connector. The piercing element can comprise or define one or more fluid conduits that allow fluid to flow from an interior of the BFS vial to an outlet port of the connector, thereby allowing the contents to be dispensed from the BFS vial. The connector can facilitate coupling of the BFS vial for subsequent administration of the contents therein to a patient. For example, the outlet port of the connector can be coupled to an administration assembly, such as a syringe, nozzle, intravenous (IV) therapy device, or another device.

Abstract: Systems and methods for disabling Blow-Fill-Seal (BFS) vials such as pre-filled vials containing a vaccine or other medicament via utilization of an assistive dispensing device to selectively compress the fluid reservoir of the BFS vial. The assistive dispensing device can aid in applying compressive force to assist in dispensing the liquid from the vial, and may also be utilized to lock in a mated position so that the BFS vial may not be reused and/or is otherwise readily identifiable as having already been administered.

Abstract: A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient may include a multi-bevel cannula piercing element such as for rotational axial engagement to pierce a seal of the BFS vial.

Abstract: A pre-filled medical delivery assembly can have first and second blow-fill-seal (BFS) modules and first and second connectors. Each BFS module can have a reservoir with a fluid agent and a neck with a seal. Each connector can have a respective recess with a piercing element. The first connector can have an outlet port, and the second connector can have an inlet/outlet (I/O) port. The connectors can be coupled together via the outlet and I/O ports. The neck of each BFS module can be inserted into the recess of the respective connector such that the piercing element breaches the seal, thereby providing a fluid path between the reservoirs. The disclosed assemblies can allow the combination of separate fluid agents via the coupled connectors and subsequently delivery of the combination as a single dose of a therapeutic agent to a patient by replacing the first connector with an administration hub.

Abstract: The invention is a single use delivery device configured to enable reconstitution of a lyophilized agent (e.g., vaccine, drug, medicament, etc.) stored within for subsequent delivery of the reconstituted fluid agent to a patient in a controlled manner and without requiring specialized skill in reconstituting the agent or administering delivery of such agent. The delivery device is prefilled with an individual dose of a lyophilized agent and configured to be filled on-site and in the field with a dose of diluent for reconstitution of the lyophilized agent, while remaining sterile and preventing the potential for contamination during the filling process. The delivery device is further configured to be rendered incapable of reuse followings its intended use of delivering the fluid agent to a patient, thereby preventing reuse of the device and reducing the risk of the spreading blood-borne diseases through reuse.

Abstract: A pre-filled medical delivery assembly can have a blow-fill-seal (BFS) module, a manifold, and a casing. The BFS module can have a pair of reservoirs, and a pair of sealed ports. Each reservoir can have a respective liquid agent therein. Each port can be in fluid communication with a respective one of the reservoirs. Part of the BFS module can be inserted into the manifold, and the casing can protect part of the BFS module exposed from the manifold. An orientation of the casing can be reversed, and the casing can be used to push the BFS module into the manifold to breach the seals and/or to compress the reservoirs to dispense the liquid agents. The disclosed assemblies can combine the liquid agents from the BFS module and deliver the combination as a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) to a patient.

Abstract: A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another.

Abstract: A fluid delivery manifold system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular manifold design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular manifold construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery manifold configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery).

Abstract: A fluid delivery manifold system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular manifold design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular manifold construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery manifold configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery).

Abstract: A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another.

Abstract: The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient.

Abstract: The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery assembly configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery). The delivery assembly is generally configured to be filled on-site and in the field and is further capable of delivery of the agent in a controlled manner and without requiring specialized skill in administering delivery of such agent.

Abstract: A pre-filled dual-chamber medical agent delivery system assembled and configured to allow delivery of a single dose of a combined therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another, such as to facilitate delivery of a reconstituted lyophilized agent to a patient.