Patents by Inventor Marc Antoine Gijbert Gilles Vooijs

Marc Antoine Gijbert Gilles Vooijs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210196681
    Abstract: The present invention relates to selective presenilin-2 ?-secretase inhibitors for use in the treatment of various diseases associated with a defect leading to Notch receptor hyperactivity. In particular the present invention relates to selective presenilin-2 ?-secretase inhibitors for use as a highly selective anti-cancer treatment. Preferred selective presenilin-2 ?-secretase inhibitors include small molecules, like 4-aminoquinolines or imidazole compounds, (monoclonal) antibodies and known ?-secretase inhibitors or analogues and combinations thereof.
    Type: Application
    Filed: August 27, 2019
    Publication date: July 1, 2021
    Inventors: Marc Antoine Gijbert Gilles Vooijs, Adrianus Johannes Groot, Jeffrey Bruce Smaill, Patrick David O'Connor, Amir Ashoorzadeh