Patents by Inventor Marc Biguet

Marc Biguet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biological dosage of peptidoglycans
    Patent number: 10351895
    Abstract: The present invention relates to a biological method for the dosage of peptidoglycans in a sample, especially a sample of glucose polymers.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: July 16, 2019
    Assignee: Roquette Freres
    Inventors: Pierre Lanos, Marc Biguet, Roselyne Bernard, Fabrice Allain, Mathieu Carpentier, Agnès Denys, Héla Hacine-Gherbi
  • BIOLOGICAL ASSAY OF PEPTIDOGLYCANS
    Publication number: 20180188233
    Abstract: The present invention relates to a biological method for assaying peptidoglycans (PGN) in a sample, particularly a sample of glucose polymers. The PGN assay includes: a) treating the glucose polymer sample by sonication, heating, and/or alkalizing; b) placing the treated sample or a dilution thereof in contact with a recombinant cell expressing an exogenous TLR2 (toll-like receptor 2) and a reporter gene directly dependent on the signaling pathway associated with the TLR2. The reporter gene codes for a colored or fluorescent protein or for a protein the activity of which is measurable with or without a substrate; c) measuring the reporter gene signal; and d) determining the amount of PUN in the sample using a standard curve of the correlation between the amount of PGN and the strength of the reporter gene signal.
    Type: Application
    Filed: November 2, 2017
    Publication date: July 5, 2018
    Inventors: Pierre Lanos, Marc Biguet, Roselyne Bernard, Fabrice Allain, Mathieu Carpentier, Agnès Denys, Héla Hacine-Gherbi
  • Biological assay of peptidoglycans
    Patent number: 9857355
    Abstract: The present invention relates to a biological method for assaying peptidoglycans (PGN) in a sample, particularly a sample of glucose polymers. The PGN assay includes: a) treating the glucose polymer sample by sonication, heating, and/or alkalizing; b) placing the treated sample or a dilution thereof in contact with a recombinant cell expressing an exogenous TLR2 (toll-like receptor 2) and a reporter gene directly dependent on the signaling pathway associated with the TLR2. The reporter gene codes for a colored or fluorescent protein or for a protein the activity of which is measurable with or without a substrate; c) measuring the reporter gene signal; and d) determining the amount of PGN in the sample using a standard curve of the correlation between the amount or PGN and the strength of the reporter gene signal.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: January 2, 2018
    Assignee: Roquette Freres
    Inventors: Pierre Lanos, Marc Biguet, Roselyne Bernard, Fabrice Allain, Mathieu Carpentier, Agnès Denys, Héla Hacine-Gherbi
  • BIOLOGICAL DOSAGE OF PEPTIDOGLYCANS
    Publication number: 20170081699
    Abstract: The present invention relates to a biological method for the dosage of peptidoglycans in a sample, especially a sample of glucose polymers.
    Type: Application
    Filed: February 5, 2015
    Publication date: March 23, 2017
    Inventors: PIERRE LANOS, MARC BIGUET, ROSELYNE BERNARD, FABRICE ALLAIN, MATHIEU CARPENTIER, AGNÉS DENYS, HÉLA HACINE-GHERBI
  • Method for purifying glucose polymers for peritoneal dialysis solutions
    Patent number: 9353192
    Abstract: The invention relates to a method of purifying glucose polymers for the production of peritoneal dialysis solutions, characterized in that it includes at least one step of processing activated carbon and/or granular black, at least one sterilizing filtration step, at least one heat treatment step, and at least one ultrafiltration step.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: May 31, 2016
    Assignee: ROQUETTE FRERES
    Inventors: Marc Biguet, Stéphane Bourdain, Pierrick Duflot
  • BIOLOGICAL ASSAY OF PEPTIDOGLYCANS
    Publication number: 20160054301
    Abstract: The present invention relates to a biological method for assaying peptidoglycans (PGN) in a sample, particularly a sample of glucose polymers. The PGN assay includes: a) treating the glucose polymer sample by sonication, heating, and/or alkalizing; b) placing the treated sample or a dilution thereof in contact with a recombinant cell expressing an exogenous TLR2 (toll-like receptor 2) and a reporter gene directly dependent on the signaling pathway associated with the TLR2. The reporter gene codes for a colored or fluorescent protein or for a protein the activity of which is measurable with or without a substrate; c) measuring the reporter gene signal; and d) determining the amount of PGN in the sample using a standard curve of the correlation between the amount or PGN and the strength of the reporter gene signal.
    Type: Application
    Filed: March 25, 2014
    Publication date: February 25, 2016
    Inventors: PIERRE LANOS, MARC BIGUET, ROSELYNE BERNARD, FABRICE ALLAIN, MATHIEU CARPENTIER, AGNÈS DENYS, HÉLA HACINE-GHERBI
  • METHOD FOR PURIFYING GLUCOSE POLYMERS FOR PERITONEAL DIALYSIS SOLUTIONS
    Publication number: 20120046460
    Abstract: The invention relates to a method of purifying glucose polymers for the production of peritoneal dialysis solutions, characterized in that it includes at least one step of processing activated carbon and/or granular black, at least one sterilizing filtration step, at least one heat treatment step, and at least one ultrafiltration step.
    Type: Application
    Filed: April 29, 2010
    Publication date: February 23, 2012
    Applicant: ROQUETTE FRERES
    Inventors: Marc Biguet, Stéphane Bourdain, Pierrick Duflot