Patents by Inventor Marc BITOUN

Marc BITOUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Allele-specific silencing therapy for dynamin 2-related diseases
    Patent number: 11926829
    Abstract: The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: March 12, 2024
    Assignees: ASSOICATION INSTITUT DE MYOLOGIE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marc Bitoun, Delphine Trochet, Bernard Prudhon
  • MEDICAL TOOL POSITIONING DEVICES, SYSTEMS, AND METHODS OF USE AND MANUFACTURE
    Publication number: 20230035207
    Abstract: Intravascular catheters that include a handle assembly with first and second handle actuators, where the actuators are adapted to separately control inner and outer catheter shafts in at least one of axial displacement, deflection, or rotation. The catheters may also include a medical tool secured to the outer shaft.
    Type: Application
    Filed: October 11, 2022
    Publication date: February 2, 2023
    Inventors: Colin Mixter, Marc Bitoun, Tom Saul
  • CABLE ROUTING AND ASSEMBLIES FOR MEDICAL DEVICE HANDLES
    Publication number: 20230012775
    Abstract: Medical devices that include a medical tool, a handle and a flexible cable bundle passing through the handle. The handles and cable routing therethrough are adapted to reduce noise within the cable.
    Type: Application
    Filed: July 13, 2022
    Publication date: January 19, 2023
    Inventors: Alan Schaer, Jerry Hopple, Daniel Lundberg, Tomas Robinson, Colin Mixter, Marc Bitoun
  • Medical tool positioning devices, systems, and methods of use and manufacture
    Patent number: 11497889
    Abstract: Intravascular catheters that include a handle assembly with first and second handle actuators, where the actuators are adapted to separately control inner and outer catheter shafts in at least one of axial displacement, deflection, or rotation. The catheters may also include a medical tool secured to the outer shaft.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: November 15, 2022
    Assignee: NuVera Medical, Inc.
    Inventors: Colin Mixter, Marc Bitoun, Tom Saul
  • MEDICAL TOOL POSITIONING DEVICES, SYSTEMS, AND METHODS OF USE AND MANUFACTURE
    Publication number: 20220168041
    Abstract: Steerable medical devices that include one or more elongate shafts and a medical tool in a distal region. The medical devices include a handle portion for controlling one or more aspects of the medical device.
    Type: Application
    Filed: April 27, 2020
    Publication date: June 2, 2022
    Inventors: Colin Mixter, Marc Bitoun, Alan Schaer, Tom Saul
  • MEDICAL TOOL POSITIONING DEVICES, SYSTEMS, AND METHODS OF USE AND MANUFACTURE
    Publication number: 20220117576
    Abstract: Steerable medical devices that include one or more elongate shafts and a medical tool in a distal region. The medical devices include a handle portion for controlling one or more aspects of the medical device.
    Type: Application
    Filed: November 13, 2019
    Publication date: April 21, 2022
    Inventors: Colin Mixter, Marc Bitoun, Tom Saul, Alan Schaer
  • Steerable medical devices, systems, and methods of use
    Patent number: 11052226
    Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: July 6, 2021
    Assignee: Kalila Medical, Inc.
    Inventors: Amr Salahieh, Jonah Lepak, Emma Lepak, Tom Saul, Jean-Pierre Dueri, Joseph Creagan Trautman, Christopher T. Cheng, Richard Joseph Renati, Colin Mixter, Marc Bitoun
  • ALLELE-SPECIFIC SILENCING THERAPY FOR DYNAMIN 2-RELATED DISEASES
    Publication number: 20210163953
    Abstract: The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation anchor overexpression of Dynamin 2.
    Type: Application
    Filed: February 3, 2021
    Publication date: June 3, 2021
    Inventors: Marc BITOUN, Delphine TROCHET, Bernard PRUDHON
  • Allele-specific silencing therapy for Dynamin 2-related diseases
    Patent number: 10947540
    Abstract: The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.
    Type: Grant
    Filed: November 19, 2017
    Date of Patent: March 16, 2021
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marc Bitoun, Delphine Trochet, Bernard Prudhon
  • MEDICAL TOOL POSITIONING DEVICES, SYSTEMS, AND METHODS OF USE AND MANUFACTURE
    Publication number: 20200061340
    Abstract: Intravascular catheters that include a handle assembly with first and second handle actuators, where the actuators are adapted to separately control inner and outer catheter shafts in at least one of axial displacement, deflection, or rotation. The catheters may also include a medical tool secured to the outer shaft.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 27, 2020
    Inventors: Colin MIXTER, Marc BITOUN, Tom SAUL
  • Medical tool positioning devices, systems, and methods of use and manufacture
    Patent number: 10537306
    Abstract: Medical tool positioning and control devices, systems, and methods. Handle assemblies that allow a steerable shaft to be steered, while allowing the separate movement of a medical tool. The handle assemblies can allow for rotation and axial movement of the medical tool, and optionally with an actuator disposed distal to a second actuator that controls steering of the steerable shaft.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: January 21, 2020
    Assignee: Shifamed Holdings, LLC
    Inventors: Alan Schaer, Tom Saul, Amr Salahieh, Colin Mixter, Joseph C. Trautman, Marc Bitoun, Todor Jeliaskov
  • ALLELE-SPECIFIC SILENCING THERAPY FOR DYNAMIN 2-RELATED DISEASES
    Publication number: 20190309305
    Abstract: The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.
    Type: Application
    Filed: November 19, 2017
    Publication date: October 10, 2019
    Inventors: Marc BITOUN, Delphine TROCHET, Bernard PRUDHON
  • Steerable medical devices, systems, and methods of use
    Patent number: 10420537
    Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices include a steerable portion with a stiffness that varies along the length of the steerable portion.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: September 24, 2019
    Assignee: Shifamed Holdings, LLC
    Inventors: Amr Salahieh, Jonah Lepak, Emma Lepak, Tom Saul, Jean-Pierre Dueri, Joseph Creagan Trautman, Christopher T. Cheng, Richard Joseph Renati, Colin Mixter, Marc Bitoun
  • MEDICAL TOOL POSITIONING DEVICES, SYSTEMS, AND METHODS OF USE AND MANUFACTURE
    Publication number: 20180279994
    Abstract: Medical tool positioning and control devices, systems, and methods. Handle assemblies that allow a steerable shaft to be steered, while allowing the separate movement of a medical tool. The handle assemblies can allow for rotation and axial movement of the medical tool, and optionally with an actuator disposed distal to a second actuator that controls steering of the steerable shaft.
    Type: Application
    Filed: January 24, 2018
    Publication date: October 4, 2018
    Inventors: Alan Schaer, Tom Saul, Amr Salahieh, Colin Mixter, Joseph C. Trautman, Marc Bitoun, Todor Jeliaskov
  • STEERABLE MEDICAL DEVICES, SYSTEMS, AND METHODS OF USE
    Publication number: 20170203077
    Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.
    Type: Application
    Filed: December 9, 2016
    Publication date: July 20, 2017
    Inventors: Amr Salahieh, Jonah Lepak, Emma Lepak, Tom Saul, Jean-Pierre Dueri, Joseph Creagan Trautman, Christopher T. Cheng, Richard Joseph Renati, Colin Mixter, Marc Bitoun
  • STEERABLE MEDICAL DEVICES, SYSTEMS, AND METHODS OF USE
    Publication number: 20170080186
    Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.
    Type: Application
    Filed: April 25, 2016
    Publication date: March 23, 2017
    Inventors: Amr SALAHIEH, Jonah LEPAK, Emma LEPAK, Tom SAUL, Jean-Pierre DUERI, Joseph Creagan TRAUTMAN, Christopher T. CHENG, Richard Joseph RENATI, Colin MIXTER, Marc BITOUN
  • STEERABLE MEDICAL DEVICES, SYSTEMS, AND METHODS OF USE
    Publication number: 20160345947
    Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices include a steerable portion with a stiffness that varies along the length of the steerable portion.
    Type: Application
    Filed: March 28, 2016
    Publication date: December 1, 2016
    Inventors: Amr SALAHIEH, Jonah LEPAK, Emma LEPAK, Tom SAUL, Jean-Pierre DUERI, Joseph Creagan TRAUTMAN, Christopher T. CHENG, Richard Joseph RENATI, Colin MIXTER, Marc BITOUN