Abstract: The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1/2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

Abstract: Systems, methods, and computer instructions are provided. The method includes retrieving a first set of a media content transmitted by a plurality of interaction clients based on a chronological order, wherein the first set of media content has been saved as part of communications of ephemeral messages between at least two users of the plurality of interaction clients. The method further includes creating a visual representation of the first set of media content, and causing to display, on at least one of the plurality of interaction clients, the visual representation the first set of media content.

Abstract: The present disclosure provides pharmaceutical compositions comprising a cannabinoid, and dosage forms comprising same, for oral delivery, such as sublingual or buccal delivery. The compositions of the present disclosure are substantially homogeneous and remain stable and monophasic upon storage. Also provided are methods of using the compositions for pain management and to treat various diseases and conditions, including dementia, sleep disorders, movement disorders, mental disorders, and multiple sclerosis.

Abstract: A system includes one or more hardware processors and at least one memory storing instructions that cause the one or more hardware processors to perform operations including retrieving a first set of a media content captured by an interaction client included in a client device, and retrieving a second set of media content captured by the interaction client included in the client device. The operations also include assigning the first set of media content a first ranking value, and assigning the second set of media content a second ranking value, creating a first visual representation of the first set of media content and a second visual representation of the second set of the second set of media content based on the first ranking value and on the second ranking value, and causing to display, on a display of the client device, the first visual representation and the second visual representation.

Abstract: The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1/2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

Abstract: The present disclosure provides pharmaceutical compositions comprising a cannabinoid, and dosage forms comprising same, for oral delivery, such as sublingual or buccal delivery. The compositions of the present disclosure are substantially homogeneous and remain stable and monophasic upon storage. Also provided are methods of using the compositions for pain management and to treat various diseases and conditions, including dementia, sleep disorders, movement disorders, mental disorders, and multiple sclerosis.

Abstract: The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1/2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

Abstract: A device may include a top region defining an opening having a top diameter. A device may include a bottom region opposite the top region and defining a base. A device may include an outer wall extending from the top region to the bottom region. A device may include an inner wall coupled to the outer wall and extending inward away from the outer wall and downward toward the base, the inner wall defining an accumulation area and having a profile configured to direct fluid into the accumulation area.

Abstract: Systems, methods, and computer instructions are provided. The method includes retrieving a first set of a media content transmitted by a plurality of interaction clients based on a chronological order, wherein the first set of media content has been saved as part of communications of ephemeral messages between at least two users of the plurality of interaction clients. The method further includes creating a visual representation of the first set of media content, and causing to display, on at least one of the plurality of interaction clients, the visual representation the first set of media content.

Abstract: A technique for deriving a mashup is described. Given a collection of media content items for sequential playback, a subset of the media content items are selected for inclusion in a mashup, based on selection criteria specified in a template associated with the featured story. The subset of media content items are then arranged in a mashup, which is prepended to the story. By automatically generating a mashup—an abbreviated version of a story—the mashup will increase user engagement and encourage sharing, because the mashup condenses the content into a more digestible and captivating format. By using optimized content selection criteria, the mashup will include only the best and most impactful moments, highlights, or key elements of the story. The shorter version grabs the viewer's attention, maintaining their interest and prompting them to share the condensed experience with others, enticing them to discover the full story.

Abstract: A system includes one or more hardware processors and at least one memory storing instructions that cause the one or more hardware processors to perform operations including retrieving a first set of a media content captured by an interaction client included in a client device, and retrieving a second set of media content captured by the interaction client included in the client device. The operations also include assigning the first set of media content a first ranking value, and assigning the second set of media content a second ranking value, creating a first visual representation of the first set of media content and a second visual representation of the second set of the second set of media content based on the first ranking value and on the second ranking value, and causing to display, on a display of the client device, the first visual representation and the second visual representation.

Abstract: A system includes one or more hardware processors and at least one memory storing instructions that cause the one or more hardware processors to perform operations including retrieving, via a client device, a first selection of a first media content captured by an interaction client included in the client device and retrieving, via the client device, a second selection of second media content captured by an application executable by the client device. The operations also include displaying the first selection of the first media content alongside the second selection of the second media content on a display of the client device, and receiving a user selection of the first selection of first media content, of the second selection of the second media content, or of a combination thereof. The operations additionally include providing the user selection as part of a message transmitted via the client device.

Abstract: A video montage is assembled by one or more processors by selecting a number of media items for use in the video montage from a collection of media items. An audio track having a theme parameter corresponding to a theme parameter of the number of media items is identified, and a video montage incorporating the media items and the audio track is generated. A data structure may specify an identity and order of the media items and a start location of the audio track, and the video montage may be created by generating individual video segments from each media item in the number of media items, and assembling the individual video segments into the video montage based on an order specified in the data structure. Updates or edits to the video montage are represented as changes to the data structure, which is used to generate an updated video montage.

Abstract: The present disclosure provides pharmaceutical compositions comprising a cannabinoid, and dosage forms comprising same, for oral delivery, such as sublingual or buccal delivery. The compositions of the present disclosure are substantially homogeneous and remain stable and monophasic upon storage. Also provided are methods of using the compositions for pain management and to treat various diseases and conditions, including dementia, sleep disorders, movement disorders, mental disorders, and multiple sclerosis.

Abstract: Method of generating selectable items providing post-viewing context actions starts with a processor receiving a media content item with first media overlay from first client device. Processor causes an active notification associated with the media content item to be displayed on a notification user interface by a second client device. Processor receives a selection of the active notification from the second client device and in response to receiving the selection of the active notification, causes the media content item to be displayed by the second client device. The processor, in response to the media content item being displayed by the second client device, causes the second client device to display the notification user interface comprising an inactive notification and a first selectable item that is associated with the first media overlay. Other embodiments are described herein.

Abstract: The present disclosure provides pharmaceutical compositions comprising a cannabinoid, and dosage forms comprising same, for oral delivery, such as sublingual or buccal delivery. The compositions of the present disclosure are substantially homogeneous and remain stable and monophasic upon storage. Also provided are methods of using the compositions for pain management and to treat various diseases and conditions, including dementia, sleep disorders, movement disorders, mental disorders, and multiple sclerosis.

Abstract: Method of generating selectable items providing post-viewing context actions starts with a processor receiving a media content item with first media overlay from first client device. Processor causes an active notification associated with the media content item to be displayed on a notification user interface by a second client device. Processor receives a selection of the active notification from the second client device and in response to receiving the selection of the active notification, causes the media content item to be displayed by the second client device. The processor, in response to the media content item being displayed by the second client device, causes the second client device to display the notification user interface comprising an inactive notification and a first selectable item that is associated with the first media overlay. Other embodiments are described herein.

Abstract: The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1/2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

Abstract: An apparatus may include a plunger and a substantially cylindrical body. The substantially cylindrical body may include an end portion having rounded edges and may define a cavity sized to receive the plunger. The substantially cylindrical body may include at least one opening extending from the cavity to an external surface. The at least one opening may a substantially irregular shape. In some embodiments, the at least one opening may extend from the cavity through a nub to the external surface. The nub may have a rounded shape. In some embodiments, the substantially irregular shape may include one of a slit, an oval shape, an elliptical shape, an hourglass shape, a rectangular shape, and a diamond shape. In some embodiments, the opening may be part of a non-cylindrical fluid passage.

Abstract: An apparatus may include a plunger and a substantially cylindrical body. The substantially cylindrical body may include an end portion having rounded edges and may define a cavity sized to receive the plunger. The substantially cylindrical body may include at least one opening extending from the cavity to an external surface. The at least one opening may a substantially irregular shape. In some embodiments, the at least one opening may extend from the cavity through a nub to the external surface. The nub may have a rounded shape. In some embodiments, the substantially irregular shape may include one of a slit, an oval shape, an elliptical shape, an hourglass shape, a rectangular shape, and a diamond shape. In some embodiments, the opening may be part of a non-cylindrical fluid passage.