Patents by Inventor Marc C. Torjman

Marc C. Torjman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10881330
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: January 5, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20200375502
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Patent number: 10842416
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: November 24, 2020
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20200360393
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine , or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-Hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: July 31, 2020
    Publication date: November 19, 2020
    Inventors: IRVING W. WAINER, RUIN MOADDEL, MICHEL BERNIER, CARLOS A. ZARATE, MARC C. TORJMAN, MICHAEL E. GOLDBERG, MARY J. TANGA
  • Publication number: 20200352456
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: Jeffrey I. Joseph, Marc C. Torjman, Denise L. Devine, Nance K. Dicciani, Channy Loeum
  • Publication number: 20200196911
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: February 27, 2020
    Publication date: June 25, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20200054278
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I JOSEPH, Noud Van HELMOND, Marc C TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Publication number: 20200054250
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20200054277
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20180098993
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: December 8, 2017
    Publication date: April 12, 2018
    Inventors: IRVING W. WAINER, RUIN MOADDEL, MICHEL BERNIER, CARLOS A. ZARATE, MARC C. TORJMAN, MICHAEL E. GOLDBERG, MARY J. TANGA
  • Patent number: 9867830
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: January 16, 2018
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH, COOPER HEALTH SYSTEM, SRI INTERNATIONAL
    Inventors: Irving W. Wainer, Ruin Moaddel, Michel Bernier, Carlos A. Zarate, Marc C. Torjman, Michael E. Goldberg, Mary J. Tanga
  • Patent number: 9650352
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain disorder (CRPS) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: May 16, 2017
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, COOPER HEALTH SYSTEM, SRI INTERNATIONAL
    Inventors: Irving W. Wainer, Ruin Moaddel, Michel Bernier, Carlos A. Zarate, Marc C. Torjman, Michael E. Goldberg, Mary J. Tanga
  • Publication number: 20170049780
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: November 2, 2016
    Publication date: February 23, 2017
    Inventors: IRVING W. WAINER, RUIN MOADDEL, MICHEL BERNIER, CARLOS A. ZARATE, MARC C. TORJMAN, MICHAEL E. GOLDBERG, MARY J. TANGA
  • Publication number: 20140296241
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain disorder (CRPS) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: October 15, 2012
    Publication date: October 2, 2014
    Inventors: Irving W. Wainer, Ruin Moaddel, Michel Bernier, Carlos A. Zarate, Marc C. Torjman, Michael E. Goldberg, Mary J. Tanga
  • Publication number: 20090264720
    Abstract: A wearable blood chemistry monitoring device is disclosed which comprises a wearable automated blood chemistry monitoring device comprising (A) a mini pump which can be, for example a peristaltic pump or syringe pump; (B) a portable form factor mechanical apparatus which preferably includes a rotatable disc with a hole which fits over the pump; (C) at least one measurement element for measuring at least one blood parameter, preferably on the disc, and preferably a series of glucose strips arranged radially in a spoke-like pattern on the disc; (D) a catheter connected to the pump via a tube; (E) a computerized device adapted to automatically measure blood analytes and blood parameters; (F) a belt adapted to hold the housing, a waste bag, and a flush solution bag; wherein the pump and disk are arranged in the housing so that a hole in a disk fits over the pump.
    Type: Application
    Filed: April 17, 2008
    Publication date: October 22, 2009
    Applicant: The Cooper Health System
    Inventors: Marc C. Torjman, Michael E. Goldberg
  • Publication number: 20090163825
    Abstract: A method and system for determining a hyper or hypoglycemic state in a diabetic patient using acetone concentration in exhaled breath by means of a nasal device containing an acetone sensor. When a hyper or hypoglycemic state is detected, an alarm is issued. The alarm can be audible and/or can be sent wirelessly to a local or remote computer system.
    Type: Application
    Filed: December 19, 2007
    Publication date: June 25, 2009
    Applicant: THE COOPER HEALTH SYSTEM
    Inventors: Robert Hirsh, Marc C. Torjman
  • Publication number: 20090124867
    Abstract: A method of and a device for non-invasively measuring the neurological depressed state and the hemodynamic state of a human patient and involving steps and units of non-invasively measuring EEG, cardiac cycle period, electrical-mechanical interval, mean arterial pressure, and ejection interval and converting the EEG into a neurological index as well as converting the measured electrical-mechanical interval, mean arterial pressure and ejection interval into the cardiac parameters such as Preload, Afterload and Contractility, which are the common cardiac parameters used by an anesthesiologist. A general anesthetic is administered based upon the converted neurological index. A vasoactive agent is independently administered based upon the converted cardiac parameters as necessary in order to restore cardiovascular homeostasis in the patient.
    Type: Application
    Filed: November 13, 2007
    Publication date: May 14, 2009
    Inventors: Robert A. Hirsh, Marc C. Torjman
  • Patent number: 6471689
    Abstract: The present invention relates to a drug delivery device which is implantable within a mammal and adapted for long-term efficient drug delivery to surrounding tissue. The drug delivery device is part of a drug delivery system that includes a catheter and a drug feed system. The drug delivery device includes a support structure that defines a drug reservoir and a capillary interface which facilitates vascular ingrowth while inhibiting blockage of drug delivery openings in the reservoir.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: October 29, 2002
    Assignee: Thomas Jefferson University
    Inventors: Jeffery I Joseph, Marc C. Torjman