Patents by Inventor Marc D'Haulluin

Marc D'Haulluin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11751779
    Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: September 12, 2023
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Boris P. Kovatchev, Marc D. Breton, Stephen D. Patek
  • Publication number: 20230260617
    Abstract: A structure, method, and computer program product for a diabetes control system provides, but is not limited thereto, the following: open-loop or closed-loop control of diabetes that adapts to individual physiologic characteristics and to the behavioral profile of each person. An exemplary aspect to this adaptation is biosystem (patient or subject) observation and modular control. Consequently, established is the fundamental architecture and the principal components for a modular system, which may include algorithmic observers of patients' behavior and metabolic state, as well as interacting control modules responsible for basal rate, insulin boluses, and hypoglycemia prevention.
    Type: Application
    Filed: April 20, 2023
    Publication date: August 17, 2023
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Boris P. KOVATCHEV, Stephen D. PATEK, Marc D. BRETON
  • Publication number: 20230256166
    Abstract: A system for activating a portable infusion pump includes a remote interaction device operated by the user for direct communication with the pump. Upon receipt of an initiate signal from the user, a computer on-board the infusion pump evaluates status metrics from the infusion pump, along with clinical information, to validate the initiate signal. With this validation, the computer identifies an appropriate response for operating the infusion pump. An indicator on the infusion pump then informs the user of the appropriate response for the user to follow for activating the infusion pump.
    Type: Application
    Filed: February 16, 2022
    Publication date: August 17, 2023
    Inventors: Paul M. DiPerna, Marc D. Goldman, Kelsie DiPerna
  • Publication number: 20230260616
    Abstract: A system for controlling the operations of a computerized device requires a sequence of two-way communications between a user and a computer. These communications both validate and control the operation of the device. A first communication from the user to the computer provides instructions that typically include changes for an operation of the device. In response, the computer requests user validation and identification. A second communication from the computer to the user then provides an operational status report of the system and a request for operational confirmation from the user, together with revalidation of user identification. An operation of the communication system is accomplished by selectively using audio, visual, and tactile signals from the user, interactively with vibrations, light variations, visual presentations and sound sequences from the device.
    Type: Application
    Filed: February 16, 2022
    Publication date: August 17, 2023
    Inventors: Paul M. DiPerna, Marc D. Goldman, Kelsie DiPerna
  • Patent number: 11723562
    Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: August 15, 2023
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Boris P. Kovatchev, Marc D. Breton, Stephen D. Patek
  • Patent number: 11727347
    Abstract: A management system for managing the utilization of item receptacles in a distribution network. Items can be transferred to recipients at a limited number of item receptacles in unit delivery facilities of the distribution network. Item retrieval behavior is tracked to determine a recipient score for known recipients. Based on the recipient scores, subsequent items to be transferred can be placed in a receptacle or a storage area based on the associated recipient score. Placement in receptacles can be prioritized to recipients with low scores indicating that the item will likely be retrieved quickly, while items addressed to recipients with high scores may not be placed into a receptacle if receptacles are scarce.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: August 15, 2023
    Assignee: United States Postal Service
    Inventors: Marc D. McCrery, Donald Eugene Irwin
  • Patent number: 11722229
    Abstract: Method, system and computer program product for providing real time detection of analyte sensor sensitivity decline is continuous glucose monitoring systems are provided.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: August 8, 2023
    Assignees: ABBOTT DIABETES CARE INC., UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Marc D. Breton, Boris P. Kovatchev, Erwin S. Budiman, Kenneth J. Doniger
  • Publication number: 20230181123
    Abstract: A system for generating a hypoglycemia risk signal associated with exercise-induced Hypoglycemia. The system can include a processor configured to obtain a blood glucose signal (BGstart), a ratio of absolute insulin on board over total daily insulin signal (IOBabs/TDI), and an initial glycemic slope signal (S0); generate a hypoglycemia risk signal based on a hypoglycemia prediction algorithm that determines the probability of a user being hypoglycemic during or after exercise based on the obtained BGstart, IOBabs/TDI and S0.
    Type: Application
    Filed: February 8, 2023
    Publication date: June 15, 2023
    Applicant: University of Virginia Patent Foundation
    Inventors: Marc D. BRETON, Najib BEN-BRAHIM
  • Patent number: 11666287
    Abstract: A system for generating a hypoglycemia risk signal associated with exercise-induced Hypoglycemia. The system can include a processor configured to obtain a blood glucose signal (BGstart), a ratio of absolute insulin on board over total daily insulin signal (IOBabs/TDI), and an initial glycemic slope signal (S0); generate a hypoglycemia risk signal based on a hypoglycemia prediction algorithm that determines the probability of a user being hypoglycemic during or after exercise based on the obtained BGstarts, IOBabs/TDI and S0.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: June 6, 2023
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Marc D. Breton, Najib Ben-Brahim
  • Publication number: 20230143826
    Abstract: A system and method of augmenting a delivery route. Exemplary methods include first location information from a first position device and receiving second location information from a second position device, storing first and second location information, and determining, based on at least one of the first and second information, a time and a location for each of a plurality of stops. Exemplary methods also include reconciling determined time and locations of each of the plurality of stops with a stored route, the stops having a stored location and a stored time associated therewith and estimating a plurality of transition times between pairs of the plurality of stops. Exemplary methods include constructing an updated timeline based on the plurality of stored stops, the plurality of determined stops, and the plurality of transition times and updating the delivery route based on the constructed timeline.
    Type: Application
    Filed: January 2, 2023
    Publication date: May 11, 2023
    Inventors: Alison Frankowski Turner, Marc D. McCrery, James J. Boldt
  • Publication number: 20230125221
    Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
    Type: Application
    Filed: December 21, 2022
    Publication date: April 27, 2023
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Boris P. KOVATCHEV, Marc D. BRETON, Stephen D. PATEK
  • Publication number: 20230129652
    Abstract: Example eye treatments detennine an area at a surface of a cornea for delivery of a cross-linking agent. The example treatments disrupt tissue at the area at the surface of the con1ea up to a depth corresponding to apical layers of superficial squamous cells of the cornea, e.g., no greater than approximately 10 ?m to approximately 15 lm. The example treatments apply a cross-linking agent to the area at the surface of the cornea. The cross-linking agent is transmitted through the disrupted area at a greater rate relative to non disrupted areas of the cornea. The example treatments deliver photoactivating light to the cornea. The photoactivating light activates the cross-linking agent to generate cross-linking activity in the cornea.
    Type: Application
    Filed: August 8, 2022
    Publication date: April 27, 2023
    Inventors: Marc D. Friedman, Alexandra Nicklin, Pavel Kamaev
  • Patent number: 11629215
    Abstract: Disclosed herein is a styrenic block copolymer [A1-B1-C1], consisting essentially of polymer blocks A1, B1 and C1. A1 is a poly(para-alkylstyrene) block having a molecular weight from 1,000 to 60,000 g/mol. B1 is a hydrogenated polyisoprene block or a hydrogenated polybutadiene block having a molecular weight from 1,000 to 100,000 g/mol. C1 is a polystyrene block having a molecular weight from 1,000 to 100,000 g/mol; or a polymer block consisting essentially of polymerized styrene units, and hydrogenated butadiene and/or isoprene units, and having a molecular weight from 1,000 to 100,000 g/mol. Prior to hydrogenation, the block B1 has a vinyl content of 5-75 mol %; and the block C1 forms 1-80 wt % of the overall weight of the block copolymer. The selectively sulfonated forms of the copolymers are useful as high dielectric materials.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: April 18, 2023
    Assignee: KRATON CORPORATION
    Inventors: Carl L Willis, Marc D Hein, Richard I Blackwell
  • Publication number: 20230103346
    Abstract: In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.
    Type: Application
    Filed: December 9, 2022
    Publication date: April 6, 2023
    Inventors: Desmond Christopher Adler, Jun A. Zhang, Mikhail Z. Smirnov, Marc D. Friedman, David Usher, Grace Elizabeth Lytle, David C. Iannetta
  • Publication number: 20230097161
    Abstract: Embodiments relate to systems and methods for informing, determining, or controlling insulin dosage. The method involves generating plural disturbance profiles, each disturbance profile being a data representation based on historical patient data pertaining to a deviation from a threshold blood glucose level. The method involves receiving current patient data. The method involves applying a predictive model so that current patient data is compared to a disturbance profile and a probability analysis is used to assess the likelihood of a disturbance profile being an anticipated disturbance profile, the anticipated disturbance profile being a disturbance profile that is determined to match with the current patient data based on the probability analysis. The method involves determining an insulin dose amount based on the anticipated disturbance profile.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 30, 2023
    Applicant: University of Virginia Patent Foundation
    Inventors: John P. CORBETT, Jose GARCIA-TIRADO, Patricio COLMEGNA, Jenny L. DIAZ-CASTAƑEDA, Marc D. BRETON
  • Patent number: 11613239
    Abstract: A pressure supply unit for a brake system including a booster body that defines an axially extending cylinder. A piston is slideable within the cylinder. The piston defines a bore that receives a spindle. The spindle is rotationally fixed and axially moveable for providing the axial movement of the piston. A motor is positioned about the spindle and is configured to axially translate the spindle and piston. A ball and socket joint connects the piston and spindle while accommodating pivoting movement of the spindle. The ball and socket joint includes a ball at a front end of the spindle and a socket in the bore of the piston which receives the ball.
    Type: Grant
    Filed: June 12, 2021
    Date of Patent: March 28, 2023
    Assignee: BWI (SHANGHAI) CO., LTD.
    Inventors: Trevor Matthew Schlangen, Eric Michael Higgins, David Fredrick Reuter, Brian Marc D'Amico, Frank Gerard Pirrello, Anthony Vincent Pesarek
  • Publication number: 20230093674
    Abstract: A portable system and method for infusing fluid medicaments to a patient through an elastomeric fluid channel includes an airtight pressure shell for holding a collapsible bag of the fluid medicament to be infused. A pressure sensor connected to the pressure shell monitors decreases below ambient pressure inside the shell to determine when the ambient pressure becomes insufficient to continue assisting the withdrawal of fluid from the collapsible bag, to an external pinch/squeeze unit. At this point, an equilibrator operates to reestablish ambient pressure in the pressure shell for continued operation. In operation, the pinch/squeeze unit exerts radial forces on the elastomeric fluid channel. These forces act to sequentially push fluid medicament for infusion to the patient when the elastomeric fluid channel is occluded and stressed, and draw fluid medicament from the collapsible bag as the elastomeric fluid channel is unstressed.
    Type: Application
    Filed: September 23, 2021
    Publication date: March 23, 2023
    Inventors: Paul M. DiPerna, Marc D. Goldman, David Neese, Patrick Hearty
  • Publication number: 20230088574
    Abstract: A portable system and method for infusing liquid medicaments to a patient through an elastomeric fluid channel includes an airtight pressure shell for holding a collapsible bag of the fluid medicament to be infused. A pressure sensor connected to the pressure shell monitors decreases below ambient pressure inside the shell to determine when the sub-ambient pressure becomes insufficient to continue assisting the withdrawal of fluid from the collapsible bag to an external pinch/squeeze unit. An equilibration valve is synchronized with the pinch/squeeze unit to reestablish ambient pressure in the pressure shell for continued operation as the pinch/squeeze unit acts to sequentially push liquid medicament for infusion into the patient.
    Type: Application
    Filed: February 2, 2022
    Publication date: March 23, 2023
    Inventors: Paul M. DiPerna, Marc D. Goldman, David Neese, Patrick Hearty
  • Publication number: 20230083484
    Abstract: Exemplary embodiments of the present disclosure include apparatus and methods to classify the plaque tissue present in the coronary artery using intravascular optical coherence tomography (IVOCT) images.
    Type: Application
    Filed: June 8, 2017
    Publication date: March 16, 2023
    Applicant: Research Development Foundation
    Inventors: Thomas E. MILNER, Vikram Lal BARUAH, Aydin ZAHEDIVASH, Austin MCELROY, Marc D. FELDMAN, Taylor Brent HOYT
  • Patent number: 11589767
    Abstract: An apparatus for measuring complex electrical admittance and/or complex electrical impedance in animal or human patients includes a first electrode and at least a second electrode which are adapted to be disposed in the patient. The apparatus includes a housing adapted to be disposed in the patient. The housing has disposed in it a stimulator in electrical communication with at least the first electrode to stimulate the first electrode with either current or voltage, a sensor in electrical communication with at least the second electrode to sense a response from the second electrode based on the stimulation of the first electrode, and a signal processor in electrical communication with the sensor to determine the complex electrical admittance or impedance of the patient.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: February 28, 2023
    Assignees: Board of Regents, The University of Texas System, Admittance Technologies, Inc.
    Inventors: Jonathan W. Valvano, Marc D. Feldman, John Porterfield, John A. Pearce, Erik Larson, Lev Shuhatovich, Kathryn Loeffler, Raffaele Cetrulo