Patents by Inventor Marc David Succi

Marc David Succi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210301254
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
    Type: Application
    Filed: March 22, 2021
    Publication date: September 30, 2021
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Patent number: 10954490
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: March 23, 2021
    Assignees: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Publication number: 20190017015
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
    Type: Application
    Filed: July 6, 2018
    Publication date: January 17, 2019
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Patent number: 10041046
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation. A single layer of epithelial cells that actively self-renews and is organized into crypts and villi clothes the intestine. It has been recently shown that the renewal of intestinal epithelium is driven by Lgr5+ intestinal stem cells (ISC) that reside at the base of these crypts (Barker et al., 2007). Lgr5+ stem cells can be isolated and cultured in vitro to form organoids containing crypt-vcllus structures that recapitulates the native intestinal epithelium (Sato et al., 2009).
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: August 7, 2018
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Patent number: 10041047
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: August 7, 2018
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Publication number: 20180042819
    Abstract: A systems and methods for determining a position of a medical tube within a patient is provided. In one example, systems and methods are provided for a self- detection positioning system that is capable of determining a location of a distal end of a medical tube placed within a patient, and notifying a physician of the location of the distal end of the medical tube.
    Type: Application
    Filed: March 8, 2016
    Publication date: February 15, 2018
    Inventors: Marc David Succi, Steven Keating, Allen Chen, Christopher Trainor, Brian Richard Daniels, Leo Tsai, Jeffrey Ishizuka, Cheryl Cui, Ali Tavakkoli
  • Publication number: 20180000348
    Abstract: The present disclosure includes a medical device which can assist in detecting tissue properties. For example, the present disclosure includes a medical device which can detect biological properties associated with the health of a patient and the tissue being examined, as well as cancerous tissue for detecting cancer in a patient. In addition, the medical device of the present disclosure can be used for collecting the data needed to create a predictive model and imaging of the biological tissue being examined.
    Type: Application
    Filed: September 18, 2017
    Publication date: January 4, 2018
    Inventors: Andrew Mina Bishara, Marc David Succi, Fransiska Putri Wina Hadiwidjana, Elishai Ezra
  • Publication number: 20170226477
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
    Type: Application
    Filed: April 21, 2017
    Publication date: August 10, 2017
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Publication number: 20160194604
    Abstract: Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation. A single layer of epithelial cells that actively self-renews and is organized into crypts and villi clothes the intestine. It has been recently shown that the renewal of intestinal epithelium is driven by Lgr5+ intestinal stem cells (ISC) that reside at the base of these crypts (Barker et al., 2007). Lgr5+ stem cells can be isolated and cultured in vitro to form organoids containing crypt-vcllus structures that recapitulates the native intestinal epithelium (Sato et al., 2009).
    Type: Application
    Filed: March 11, 2014
    Publication date: July 7, 2016
    Inventors: Jeffrey Michael Karp, Xiaolei Yin, Marc David Succi, Robert Samuel Langer
  • Publication number: 20140052026
    Abstract: The present disclosure includes a medical device which can assist in detecting tissue stiffness. For example, the present disclosure includes a medical device which can detect tissue stiffness associated with cancerous tissue for detecting cancer in a patient. In addition, the medical device of the present disclosure can be used for conducting a clinical breast exam.
    Type: Application
    Filed: August 19, 2013
    Publication date: February 20, 2014
    Applicant: AUGMENTED MEDICAL INTELLIGENCE LABS, INC.
    Inventors: Andrew Mina Bishara, Marc David Succi, Fransiska Putri Wina Hadiwidjana, Elishai Ezra