Patents by Inventor Marc De Gasparo

Marc De Gasparo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120010258
    Abstract: The invention relates to the use of an AT1 receptor antagonist or an AT2 receptor modulator, respectively, or a pharmaceutically acceptable salt thereof, for producing a pharmaceutical preparation for the treatment of conditions or diseases associated with the increase of AT1 receptors in the sub-epithelial area or increase of AT2 receptors in the epithelia.
    Type: Application
    Filed: June 13, 2011
    Publication date: January 12, 2012
    Inventors: Gillian Rosemary Bullock, Marc De Gasparo, Sabina Maria Ganter
  • Publication number: 20100120877
    Abstract: The invention relates to the use of an AT1 receptor antagonist or or an AT2 receptor modulator, respectively, or a pharmaceutically acceptable salt thereof, for producing a pharmaceutical preparation for the treatment of conditions or diseases associated with the increase of AT1 receptors in the sub-epithelial area or increase of AT2 receptors in the epithelia.
    Type: Application
    Filed: September 25, 2008
    Publication date: May 13, 2010
    Inventors: Gillian Rosemary Bullock, Marc De Gasparo, Sabina Maria Ganter
  • Publication number: 20070105894
    Abstract: The invention relates to a combination of at least two therapeutic combination components selected from the group consisting of (i) an AT1-receptor antagonist or an AT1 receptor antagonist combined with a diuretic or, in each case, a pharmaceutically acceptable salt thereof, (ii) a HMG-Co-A reductase inhibitor or a pharmaceutically acceptable salt thereof and (iii) an ACE inhibitor or a pharmaceutically acceptable salt thereof for use in the prevention of, delay of progression of, treatment of a disease or condition selected from the group consisting of hyperlipidaemia and dyslipidemia, atherosclerosis, insulin resistance and syndrome X, diabetes mellitus type 2, obesity, nephropathy, renal failure, e.g.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 10, 2007
    Inventors: Marc De Gasparo, Kurt Graves
  • Publication number: 20040023840
    Abstract: The invention relates to a combination of at least two therapeutic combination components selected from the group consisting of (i) an AT1-receptor antagonist or an AT1 receptor antagonist combined with a diuretic or, in each case, a pharmaceutically acceptable salt thereof, (ii) a HMG-Co-A reductase inhibitor or a pharmaceutically acceptable salt thereof and (iii) an ACE inhibitor or a pharmaceutically acceptable salt thereof for use in the prevention of, delay of progression of, treatment of selected diseases and conditions.
    Type: Application
    Filed: January 3, 2003
    Publication date: February 5, 2004
    Inventors: Marc De Gasparo, Kurt C. Graves
  • Publication number: 20020155986
    Abstract: The invention relates to the use of an AT1 receptor antagonist or or an AT2 receptor modulator, respectively, or a pharmaceutically acceptable salt thereof, for producing a pharmaceutical preparation for the treatment of conditions or diseases associated with the increase of AT1 receptors in the sub-epithelial area or increase of AT2 receptors in the epithelia.
    Type: Application
    Filed: February 6, 2002
    Publication date: October 24, 2002
    Inventors: Gillian Rosemary Bullock, Marc De Gasparo, Sabina Maria Ganter
  • Patent number: 6465502
    Abstract: The invention relates to the use of an AT1 receptor antagonist or or an AT2 receptor modulator, respectively, or a pharmaceutically acceptable salt thereof, for producing a pharmaceutical preparation for the treatment of conditions or diseases associated with the increase of AT1 receptors in the sub-epithelial area or increase of AT2 receptors in the epithelia.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: October 15, 2002
    Assignee: Novartis AG
    Inventors: Gillian Rosemary Bullock, Marc De Gasparo, Sabina Maria Ganter
  • Patent number: 6395728
    Abstract: The invention relates to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, myocardial infarction and its sequelae, supraventricular and ventricular arrhythmias, atrial fibrillation or atrial flutter, atherosclerosis, angina (whether stable or ustable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetessecondary aldosteronism, primary and secondary pulmonary hyperaldosteronism, primary and pulmonary hypertension, renal failure conditions, such as diabetic nephropathy,glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), and stroke, comprising admi
    Type: Grant
    Filed: January 9, 2001
    Date of Patent: May 28, 2002
    Assignee: Novartis AG
    Inventors: Randy Lee Webb, Marc de Gasparo
  • Publication number: 20010049384
    Abstract: The invention relates to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, myocardial infarction and its sequelae, supraventricular and ventricular arrhythmias, atrial fibrillation or atrial flutter, atherosclerosis, angina (whether stable or ustable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetessecondary aldosteronism, primary and secondary pulmonary hyperaldosteronism, primary and pulmonary hypertension, renal failure conditions, such as diabetic nephropathy,glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), and stroke, comprising administering
    Type: Application
    Filed: January 9, 2001
    Publication date: December 6, 2001
    Inventors: Randy Lee Webb, Marc de Gasparo
  • Patent number: 6211217
    Abstract: Disclosed are methods of reducing fibrosis and adhesion formation in a surgical patient wherein the AT1 receptor antagonist, the compound (S)-N-(1-carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2′(1H-tetrazol-5-yl)biphenyl-4-yl-methyl]amine (valsartan) of formula or a salt thereof, in particular a pharmaceutically acceptable salt thereof, is administered to the patient. In particular, disclosed are methods of reducing pericardial fibrosis and pericardial adhesion formation which results from cardiac surgery.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: April 3, 2001
    Assignee: Novartis AG
    Inventors: Francis G. Spinale, Marc de Gasparo
  • Patent number: 6204281
    Abstract: The invention relates to a method for the treatment or prevention of a condition or disease selected from the group consisting of hypertension, (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, myocardial infarction and its sequelae, supraventricular and ventricular arrhythmias, atrial fibrillation or atrial flutter, atherosclerosis, angina (whether stable or ustable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetes, hypertension in patients with NIDDM, secondary aldosteronism, primary and secondary pulmonary hyperaldosteronism, primary and pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzhei
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: March 20, 2001
    Assignee: Novartis AG
    Inventors: Randy Lee Webb, Marc de Gasparo
  • Patent number: 6174910
    Abstract: The invention provides the use of an AT1 receptor antagonist, or a pharmaceutical salt thereof, for producing a pharmaceutical preparation for the stimulation of apoptosis and for the treatment of pathological symptoms which are substantially reduced, halted or prevented by apoptosis, and also corresponding pharmaceutical preparations.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: January 16, 2001
    Assignee: Novartis AG
    Inventors: Marc De Gasparo, Gillian Rosemary Bullock, Leoluca Criscione