Patents by Inventor Marc De Maeyer

Marc De Maeyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9499563
    Abstract: The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: November 22, 2016
    Assignee: Katholieke Universiteit Leuven
    Inventors: Dorothée Bardiot, Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Publication number: 20150336965
    Abstract: The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection.
    Type: Application
    Filed: August 3, 2015
    Publication date: November 26, 2015
    Inventors: Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Patent number: 9132129
    Abstract: The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: September 15, 2015
    Assignee: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Publication number: 20150051195
    Abstract: The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
    Type: Application
    Filed: October 30, 2014
    Publication date: February 19, 2015
    Inventors: Patrick Chaltin, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Wim Smets, Arnout Voet, Frauke Christ
  • Patent number: 8906906
    Abstract: The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: December 9, 2014
    Assignee: Katholieke Universiteit Leuven
    Inventors: Patrick Chaltin, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Wim Smets, Arnout Voet, Frauke Christ
  • Publication number: 20140296272
    Abstract: The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
    Type: Application
    Filed: June 17, 2014
    Publication date: October 2, 2014
    Inventors: Dorothée Bardiot, Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Patent number: 8785638
    Abstract: The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: July 22, 2014
    Assignee: Katholieke Universiteit Leuven
    Inventors: Dorothée Bardiot, Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Publication number: 20130245049
    Abstract: The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection.
    Type: Application
    Filed: November 15, 2011
    Publication date: September 19, 2013
    Applicant: Katholieke Universiteit Leuven
    Inventors: Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Publication number: 20120316161
    Abstract: The present invention relates to compounds of formula (A) as defined herein having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
    Type: Application
    Filed: December 20, 2010
    Publication date: December 13, 2012
    Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Gunter Carlens, Patrick Chaltin, Frauke Christ, Zeger Debyser, Arnaud Marchand, Damien Marchand, Arnout Voet, Marc De Maeyer
  • Publication number: 20120129840
    Abstract: The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
    Type: Application
    Filed: August 5, 2010
    Publication date: May 24, 2012
    Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Patrick Chaltin, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Wim Smets, Arnout Voet, Frauke Christ
  • Publication number: 20120059028
    Abstract: The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
    Type: Application
    Filed: May 17, 2010
    Publication date: March 8, 2012
    Applicant: Katholieke Universiteit Leuven
    Inventors: Dorothée Bardiot, Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Publication number: 20080121494
    Abstract: A movable table for serving out food is described, which has an operating position for serving out food, and a transportation position for moving of the table. The movable table comprises at least two modules, each module comprising an automated transferring device, e.g. at least one conveyor belt, for transferring food receptacles from one end of the table to an opposite end thereof. The upper side of the transferring device in operating position forms a working surface of the table. The table is furthermore provided with means for fixing a support above the table surface. Each module may be provided with a transferring mechanism for transferring food receptacles on the automated transferring device of that module when the table is in the operating position. Said transferring mechanism of a module operatively connects as the table is into the operating position and operatively disengages when the table is brought into the transportation position.
    Type: Application
    Filed: January 3, 2008
    Publication date: May 29, 2008
    Inventor: Marc De Maeyer
  • Patent number: 7337895
    Abstract: A movable table for serving out food has an operating position for serving out food, and a transportation position for moving of the table. The movable table comprises at least two modules, each module comprising an automated transferring device, e.g. at least one conveyor belt, for transferring food receptacles from one end of the table to an opposite end thereof. The upper side of the transferring device in operating position forms a working surface of the table. The table is furthermore adapted for fixing a support above the table surface. Each module may be provided with a transferring mechanism for transferring food receptacles on the automated transferring device of that module when the table is in the operating position. The transferring mechanism of a module operatively connects as the table is into the operating position and operatively disengages when the table is brought into the transportation position.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: March 4, 2008
    Inventor: Marc De Maeyer
  • Publication number: 20060283686
    Abstract: A movable table for serving out food is described, which has an operating position for serving out food, and a transportation position for moving of the table. The movable table comprises at least two modules, each module comprising an automated transferring device, e.g. at least one conveyor belt, for transferring food receptacles from one end of the table to an opposite end thereof. The upper side of the transferring device in operating position forms a working surface of the table. The table is furthermore provided with means for fixing a support above the table surface. Each module may be provided with a transferring mechanism for transferring food receptacles on the automated transferring device of that module when the table is in the operating position. Said transferring mechanism of a module operatively connects as the table is into the operating position and operatively disengages when the table is brought into the transportation position.
    Type: Application
    Filed: April 7, 2004
    Publication date: December 21, 2006
    Inventor: Marc De Maeyer
  • Patent number: 5807980
    Abstract: Compounds derived from BPTI which inhibit factor VIIa-TF complex with an inhibition constant of less than 500 nM, their pharmaceutical compositions, and methods of use. Also disclosed are isolated nucleic acid segments encoding for the compounds, vectors comprising the nucleic acid segment and promoter, transformed host cells, and a method for preparing the compounds using transformed host cells.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: September 15, 1998
    Assignee: Corvas International, Inc.
    Inventors: Ignace Lasters, Marc De Maeyer, William Charles Ripka
  • Patent number: 5747449
    Abstract: A compound derived from BPTI which inhibits Factor Xa with an inhibition constant less than 50 nM.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: May 5, 1998
    Assignee: Corvas International, Inc.
    Inventors: Ignace Lasters, Marc De Maeyer, William Charles Ripka