Patents by Inventor Marc E. Voorhees
Marc E. Voorhees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148952Abstract: Disclosed are systems and methods for hyperthermic cancer treatment. For example, a system can include a heat exchanger, a control module, a primary fluid delivery line (“FDL”), an intravenous catheter, and a peristaltic pump. The control module can include at least a hydraulic system configured to provide a temperature-controlled fluid. The primary FDL can be configured to convey the temperature-controlled fluid to the heat exchanger as a supply fluid and back to the hydraulic system as a return fluid. The intravenous catheter can include a primary lumen configured to convey blood of the patient to the heat exchanger as well as a secondary lumen configured to convey the blood back to the patient using the peristaltic pump. The catheter can also include a thermistor for determining a core body temperature of the patient to ensure the patient is in a hyperthermic state before administering a cancer treatment to the patient.Type: ApplicationFiled: March 8, 2022Publication date: May 9, 2024Inventors: Michael R. Hoglund, Marc E. Voorhees
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Publication number: 20240099878Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca/hr-cm-° C.Type: ApplicationFiled: December 11, 2023Publication date: March 28, 2024Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir D. Hart
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Patent number: 11865034Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca//hr-cm-° C.Type: GrantFiled: January 31, 2022Date of Patent: January 9, 2024Assignee: Medivance IncorporatedInventors: Marc E. Voorhees, Michael R. Hoglund, Keir D. Hart
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Publication number: 20230405205Abstract: A system for extracorporeal blood temperature control includes a heat exchanger configured to cool a circulated fluid, a thermal exchange module including a first volume fluidly isolated from a second volume, a fluid pump, a blood pump, and a controller. The fluid pump can pump the circulated fluid through the heat exchanger and the first volume of the thermal exchange module. The fluid pump can establish a negative pressure within the first volume of the thermal exchange module The blood pump can pump blood through a first blood flow line, the second volume of the thermal exchange module, and a second blood flow line. The controller can cool the blood by controlling thermal exchange between the circulated fluid pumped through the first volume of the thermal exchange module and the blood pumped through the second volume of the thermal exchange module.Type: ApplicationFiled: September 1, 2023Publication date: December 21, 2023Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
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Patent number: 11752251Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly-isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.Type: GrantFiled: October 9, 2019Date of Patent: September 12, 2023Assignee: Medivance IncorporatedInventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
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Publication number: 20230181352Abstract: A patient temperature control system is disclosed that includes a heat exchange system configured to heat or cool a fluid, a circulating pump configured to circulate the fluid through the heat exchanger and at least one interconnectable pad and a control one or more processors and a non-transitory computer-readable medium having stored thereon logic. The logic, when executed by the one or more processors, causes operations including initiation of a targeted temperature management therapy, obtaining of measurements from fluid temperature sensors, a volumetric flow rate sensor and a patient temperature sensor, determining a level of patient heat generation based on one or more of the obtained measurements, and transmitting, via one or more wireless signals, data indicating the level of patient heat generation to a network device.Type: ApplicationFiled: May 26, 2021Publication date: June 15, 2023Inventors: Marc E. Voorhees, Michelle Merrill, Karine Rastatter
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Publication number: 20230077318Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca//hr-cm-° C.Type: ApplicationFiled: January 31, 2022Publication date: March 9, 2023Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir D. Hart
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Patent number: 11446176Abstract: A system and method are provided, the system including a monitoring device to monitor sensory data of a patient and to provide a sensory data response thereto, and a control unit configurable to cool or warm circulated fluid through at least one contact pad for thermal exchange with the patient. The monitoring device can be configured to monitor a patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. A processor can be provided to process the monitoring signal and provide an output employable by medical personnel. The processor can be programmed to control automatically a temperature of the circulated fluid to cool or warm the patient in different treatment phases in accordance with a predetermined protocol, and process the sensory data signal to provide an output signal indicative of a sensory measurement.Type: GrantFiled: March 16, 2020Date of Patent: September 20, 2022Assignee: Medivance IncorporatedInventors: Marc E. Voorhees, Gary A. Carson, Gary Gruszecki
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Publication number: 20220151821Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer can include an ultraviolet light-cured composition with a cross-linking copolymer, water, and glycerol. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca//hr-cm-° C.Type: ApplicationFiled: January 31, 2022Publication date: May 19, 2022Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir D. Hart
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Patent number: 11234859Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer comprises an ultra violet light-cured composition that includes a cross-linking copolymer in an amount of between about 15% to 30% by weight of the composition, water in an amount of between about 15% to 40% by weight of the composition, and glycerol in an amount of between about 25% to 35% by weight of the composition. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 cal/hr-cm-° C.Type: GrantFiled: October 9, 2019Date of Patent: February 1, 2022Assignee: Medivance IncorporatedInventors: Marc E. Voorhees, Michael R. Hoglund, Keir David Hart
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Publication number: 20200214880Abstract: A system and method are provided, the system including a monitoring device to monitor sensory data of a patient and to provide a sensory data response thereto, and a control unit configurable to cool or warm circulated fluid through at least one contact pad for thermal exchange with the patient. The monitoring device can be configured to monitor a patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. A processor can be provided to process the monitoring signal and provide an output employable by medical personnel. The processor can be programmed to control automatically a temperature of the circulated fluid to cool or warm the patient in different treatment phases in accordance with a predetermined protocol, and process the sensory data signal to provide an output signal indicative of a sensory measurement.Type: ApplicationFiled: March 16, 2020Publication date: July 9, 2020Inventors: Marc E. Voorhees, Gary A. Carson, Gary Gruszecki
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Publication number: 20200155341Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer comprises an ultra violet light-cured composition that includes a cross-linking copolymer in an amount of between about 15% to 30% by weight of the composition, water in an amount of between about 15% to 40% by weight of the composition, and glycerol in an amount of between about 25% to 35% by weight of the composition. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 cal/hr-cm-° C.Type: ApplicationFiled: October 9, 2019Publication date: May 21, 2020Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir David Hart
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Publication number: 20200086033Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly-isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.Type: ApplicationFiled: October 9, 2019Publication date: March 19, 2020Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
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Patent number: 10441707Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.Type: GrantFiled: August 5, 2015Date of Patent: October 15, 2019Assignee: MEDIVANCE INCORPORATEDInventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
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Patent number: 10441458Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer comprises an ultra violet light-cured composition that includes a cross-linking copolymer in an amount of between about 15% to 30% by weight of the composition, water in an amount of between about 15% to 40% by weight of the composition, and glycerol in an amount of between about 25% to 35% by weight of the composition. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca/hr-cm-° C.Type: GrantFiled: January 29, 2016Date of Patent: October 15, 2019Assignee: MEDICANCE INCORPORATEDInventors: Marc E. Voorhees, Michael R. Hoglund, Keir David Hart
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Publication number: 20170246374Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.Type: ApplicationFiled: August 5, 2015Publication date: August 31, 2017Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
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Publication number: 20170189225Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer comprises an ultra violet light-cured composition that includes a cross-linking copolymer in an amount of between about 15% to 30% by weight of the composition, water in an amount of between about 15% to 40% by weight of the composition, and glycerol in an amount of between about 25% to 35% by weight of the composition. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 ca//hr-cm-° C.Type: ApplicationFiled: January 29, 2016Publication date: July 6, 2017Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir David Hart
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Patent number: 9622907Abstract: A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.Type: GrantFiled: October 26, 2012Date of Patent: April 18, 2017Assignee: Medivance IncorporatedInventors: Gary A. Carson, Michael R. Hoglund, Marc E. Voorhees
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Publication number: 20140214138Abstract: A medical pad having a dual layer portion including a fluid circulation and containment layers and a single layer portion including the fluid circulation layer. The fluid circulation layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the fluid circulation layer. A fluid containment layer of the medical pad is interconnected to a portion of second side of the fluid circulation layer, opposite to the first side of the fluid circulation layer. The fluid containment layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. Portions of the fluid circulation layer that extend beyond the fluid containment layer define flaps that provide additional area for fluid circulation.Type: ApplicationFiled: August 16, 2013Publication date: July 31, 2014Applicant: Medivance IncorporatedInventors: Marc E. Voorhees, Owen Mandry
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Patent number: 8047010Abstract: A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.Type: GrantFiled: May 18, 2009Date of Patent: November 1, 2011Assignee: Medivance IncorporatedInventors: Gary A. Carson, Marc E. Voorhees