Patents by Inventor Marc Ehlers

Marc Ehlers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sialylated antigen-specific antibodies for treatment or prophylaxis of unwanted inflammatory immune reactions and methods of producing them
    Publication number: 20120058111
    Abstract: The present invention is directed to a sialylated isolated antibody specific for an antigen selected from autoimmune antigens, allergens, MHC molecules or Rhesus factor D antigen, comprising an Fc-portion of IgG type, and exhibiting a sialic acid residue at the Fc-portion for use in treatment and/or prophylaxis of autoimmune disease, allergy, transplant rejection or Rhesus factor D reactivity and to methods of producing such an antibody.
    Type: Application
    Filed: March 26, 2010
    Publication date: March 8, 2012
    Inventors: Marc Ehlers, Constanze Hess, Alexandra Katharina Lorenz, André Winkler
  • IL-6 mutein and DNA encoding thereto
    Patent number: 6280975
    Abstract: The present invention relates to a new IL-6 mutein, a DNA sequence coding for it, its use in therapy as well as a pharmaceutical composition comprising it. It is a potent IL-6 antagonist and can be advantageously used as a medicament in the treatment of diseases in which IL-6 has a pathogenetic action, such as, for example, plasmocytoma/myeloma, osteoporosis and neoplastic and auotoimmune diseases.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: August 28, 2001
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Marc Ehlers, Stefan Rose-John, Joachim Grotzinger