Abstract: The present invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to the pathological form of TDP-43, which characterizes various TDP-43 proteinopathies. The antibodies, and antigen binding fragments thereof, decrease TDP-43 aggregation observed under pathological conditions. The invention also relates to nucleic acids that encode, and to cells that express such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments in the diagnosis, treatment and prevention of TDP-43 proteinopathies.

Abstract: The present invention relates to a stackable and collapsible transport box. The transport box comprises a base plate, two shorter side walls which are mutually opposite and collapsible in a lower first plane connected to the base plate via hinge joints and two shorter side walls which are mutually opposite and collapsible in a higher second plane, also connected to the base plate via hinge joints. The base plate comprises a plurality of supporting pillars arranged as tube elements beneath the base plate and arranged as angle elements above the base plate. The angle elements are provided with step-like arrangements so that the angle elements may receive tube elements of another similar or identical transport box in the collapsed state.

Abstract: The present invention relates to a stackable and collapsible transport box. The transport box comprises a base plate, two shorter side walls which are mutually opposite and collapsible in a lower first plane connected to the base plate via hinge joints and two shorter side walls which are mutually opposite and collapsible in a higher second plane, also connected to the base plate via hinge joints. The base plate comprises a plurality of supporting pillars arranged as tubular elements beneath the base plate and arranged as angular elements above the base plate. The angular elements are provided with step-like arrangements so that the angular elements may receive tubular elements of another similar or identical transport box in the collapsed state.

Abstract: Novel runners for a transport box, a pallet or the like are described which are provided with an arrangement allowing assembly of several similar or diametrically opposed runner elements into a runner.