Abstract: The method for calibrating a micromachined inertial angle sensor (2) comprising a support, at least one vibrating mass movable relative to the support, at least one transducer for exciting vibrating movement of the vibrating mass, at least one transducer for detecting a vibration of the vibrating mass, and at least one electrostatic transducer being capable of applying an adjustable electrostatic stiffness to the vibrating mass, the calibration method comprising the steps of the angle sensor receiving a predetermined vibrational excitation emitted by an excitation device (18) separate from the excitation transducer; the detection transducer measuring the vibration of the vibrating mass to obtain a measurement signal (Sm) from said measurement by the detection transducer; and transforming; determining, adjusting, and applying the electrostatic stiffness.

Abstract: The present technology provides the crystalline phosphate, malonate, and malate salts of 3-(2-amino-1,3-benzoxazol-5-yl)-1-(1,3-dimethylbutyl)pyrazolo[3,4-d]pyrimidine-4,6-diamine. The present technology further provides methods for preparing the various forms, compositions containing them, and methods related to modulation of mTOR. In particular, the present crystalline compounds and compositions may be used to treat mTOR-mediated disorders and conditions, including, e.g., dermatological disorders related to a disorder of keratinization with a proliferative, inflammatory and/or immuno-allergic component.

Abstract: The method for calibrating a micromachined inertial angle sensor (2) comprising a support, at least one vibrating mass movable relative to the support, at least one transducer for exciting vibrating movement of the vibrating mass, at least one transducer for detecting a vibration of the vibrating mass, and at least one electrostatic transducer being capable of applying an adjustable electrostatic stiffness to the vibrating mass, the calibration method comprising the steps of the angle sensor receiving a predetermined vibrational excitation emitted by an excitation device (18) separate from the excitation transducer; the detection transducer measuring the vibration of the vibrating mass to obtain a measurement signal (Sm) from said measurement by the detection transducer; and transforming; determining, adjusting, and applying the electrostatic stiffness.

Abstract: A compensation method for a magnetic field on board a vehicle including the steps carried out by computer and consisting of: for each measuring time Ti, i=1 to N with N>1, collecting the measured values of the 3D magnetic field Hmi and those of the angles ?i and ?i, where ?i is the pitch of the vehicle ?i is the roll of the vehicle; determining a matrix A and a vector B as a function at least of the collected magnetic field values Hmi and angles ?i et ?i, i=1 to N, the matrix A representing the soft iron and nonalignment disruptions and the vector B representing the hard iron disruptions; and the method comprising a step for estimating (105) the pair (A,B) minimizing the expression ? i = 1 ? à ? ? N ? ? ( ? A ? ( Hm i - B ) ? - 1 N ? ? i = 1 ? à ? N ? ? ( ? A ? ( Hm i - B ) ? ) ) 2 + ? i = 1 ? ? à ? N ? ? ( V i ? A ? ( Hm i - B ) - 1 N ? ? i = 1 ? à ? N ? ? ( V i ? A ? ( Hm i - B ) )

Abstract: A compensation method for a magnetic field on board a vehicle including the steps carried out by computer and consisting of: for each measuring time Ti, i=1 to N with N>1, collecting the measured values of the 3D magnetic field Hmi and those of the angles ?i and ?i, where ?i is the pitch of the vehicle ?i is the roll of the vehicle; determining a matrix A and a vector B as a function at least of the collected magnetic field values Hmi and angles ?i et ?i, i=1 to N, the matrix A representing the soft iron and nonalignment disruptions and the vector B representing the hard iron disruptions; and the method comprising a step for estimating (105) the pair (A,B) minimizing the expression ? i = 1 ? à ? ? N ? ? ( ? A ? ( Hm i - B ) ? - 1 N ? ? i = 1 ? à ? N ? ? ( ? A ? ( Hm i - B ) ? ) ) 2 + ? i = 1 ? ? à ? N ? ? ( V i ? A ? ( Hm i - B ) - 1 N ? ? i = 1 ? à ? N ? ? ( V i ? A ? ( Hm i - B ) )

Abstract: The Invention relates to a method for preparing a combretastatin (A): formula (I) in the form of a base or of an addition salt with an acid, which comprises coupling, in the presence of a base and of T3P, the salt of the (Z)-amino compound of formula (II) with a doubly protected L-serine derivative of formula (III) in which PG denotes a group protecting the amine function, so as to obtain the compound of formula (Z)-(Ib): formula (IV), then deprotecting and opening the ring of (Z)-(Ib) in the presence of an acid, so as to obtain the combretastatin (A) in the form of a salt; and, optionally, adding a base, so as to obtain the combretastatin (A) in the form of a base, the salt of the (Z)-amino compound having been obtained by enrichment of the salt of the amino compound of formula (V) in (Z) isomer.