Patents by Inventor Marc Gregoire

Marc Gregoire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240002277
    Abstract: A glass material that includes: from about 0.45 to about 0.86 mole fraction of SiO2; from about 0.05 to about 0.43 mole fraction of: Y2O3, BaO, or a combination of Y2O3 and BaO; and optionally Ta2O5. The sum of the Y2O3, the BaO and the optional Ta2O5 is from about 0.10 to about 0.50 mole fraction. The glass includes less than 0.01 mole fraction of Na2O and less than 0.01 mole fraction of K2O. The glass material may be in the form of microspheres. The microspheres may be used for vascular embolization and/or radiologic imaging.
    Type: Application
    Filed: November 15, 2021
    Publication date: January 4, 2024
    Inventors: Sharon LEGERE, Daniel BOYD, Kathleen O'CONNELL, Marc GREGOIRE, F. Anthony HEADLEY, JR.
  • Publication number: 20220211887
    Abstract: The present disclosure provides a composition that includes a mixture of (i) radioactive microparticles; and (ii) non-radioactive microparticles. The radioactive microparticles may be suitable to treat a vascularized tumour, such as a liver tumour or a metastasized liver tumour. The radioactive microparticles and the non-radioactive microparticles may have substantially the same resistance when flowing in a liquid through a conduit. The present disclosure also provides methods of making and methods of using mixtures of microparticles.
    Type: Application
    Filed: September 15, 2020
    Publication date: July 7, 2022
    Inventors: Marc GREGOIRE, F. Anthony HEADLEY, Jr.
  • Publication number: 20220177351
    Abstract: A glass material that includes: from about 0.55 to about 0.85 mole fraction of SiO2; from about 0.01 to about 0.23 mole fraction of Na2O, K2O, or a combination of Na2O and K2O; from about 0.05 to about 0.28 mole fraction of: Y2O3, BaO, or a combination of Y2O3 and BaO; and optionally Ta2O5. In the glass material, the sum of the Y2O3, the BaO and the optional Ta2O5 is from about 0.10 to about 0.31 mole fraction. The glass material may be in the form of microspheres. The microspheres may be used for vascular embolization and/or radiologic imaging.
    Type: Application
    Filed: June 1, 2020
    Publication date: June 9, 2022
    Inventors: Sharon LEGERE, Daniel BOYD, Kathleen O'CONNELL, Marc GREGOIRE, F. Anthony HEADLEY, Jr.
  • Publication number: 20220087646
    Abstract: At least one embodiment of an ultrasonic periodontal probe, the ultrasonic periodontal probe comprising a grip portion having a longitudinal axis, a support member comprising a part having a longitudinal axis different from the longitudinal axis of the grip portion, and an ultrasonic device fastened to the grip portion via the support member, wherein the ultrasonic device is configured for emitting ultrasound signals within at least two emitting cones and for receiving corresponding echoed ultrasound signals, the at least two emitting cones extending in opposite directions with regard to a plane comprising the longitudinal axis of the grip portion.
    Type: Application
    Filed: January 16, 2020
    Publication date: March 24, 2022
    Inventors: Arnaud CAPRI, David ROUDERGUES, Jean-Marc INGLESE, Herve JOSSO, Edward SHELLARD, Stephanie CHEVALLIOT, Jean-Marc GREGOIRE, Frederic OSSANT, Aline BANQUART
  • Patent number: 11045166
    Abstract: This invention concerns an ultrasonic dental imaging probe (1), typically comprising several transducers (4) arranged to operate as a transmitter and a receiver, and in particular arranged to transmit ultrasonic waves at a frequency of at least 10 MHz, and optionally several transducers (4) arranged to operate as a transmitter and a receiver and arranged to transmit ultrasonic waves at a frequency of less than 4 MHz. The transducers are mounted on a flexible support (3), secured to a rigid frame (2) typically in a “U” shape. The invention also concerns a device comprising one such probe.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: June 29, 2021
    Inventors: Jean-Pierre Gerbaulet, Jean-Marc Gregoire, Franck Levassort
  • Patent number: 10980873
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: April 20, 2021
    Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE NANTES
    Inventors: Frédéric Tangy, Marc Gregoire, Jean-François Fonteneau, Jean-Baptiste Guillerme, Chantal Combredet
  • Publication number: 20200016260
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Application
    Filed: June 3, 2019
    Publication date: January 16, 2020
    Inventors: Frédéric TANGY, Marc GREGOIRE, Jean-François FONTENEAU, Jean-Baptiste GUILLERME, Chantal COMBREDET
  • Patent number: 10314905
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumor or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: June 11, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), INSTITUT PASTEUR, UNIVERSITE DE NANTES
    Inventors: Frédéric Tangy, Marc Gregoire, Jean-François Fonteneau, Jean-Baptiste Guillerme, Chantal Combredet
  • Publication number: 20180221469
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Application
    Filed: January 25, 2018
    Publication date: August 9, 2018
    Inventors: Frédéric TANGY, Marc GREGOIRE, Jean-François FONTENEAU, Jean-Baptiste GUILLERME, Chantal COMBREDET
  • Patent number: 9889193
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumor or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: February 13, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCENTIFIQUE (CNRS), INSITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), INSTITUT PASTEUR, UNIVERSITE DE NANTES
    Inventors: Frédéric Tangy, Marc Gregoire, Jean-François Fonteneau, Jean-Baptiste Guillerme, Chantal Combredet
  • Patent number: 9636395
    Abstract: The present invention relates to the use of at least one attenuated measles virus for the manufacture of a medicament intended for treating malignant mesothelioma in an individual.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: May 2, 2017
    Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Anne Gauvrit, Frédéric Tangy, Marc Gregoire
  • Publication number: 20150359873
    Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 17, 2015
    Inventors: Frédéric TANGY, Marc GREGOIRE, Jean-François FONTENEAU, Jean-Baptiste GUILLERME, Chantal COMBREDET
  • Publication number: 20150313572
    Abstract: This invention concerns an ultrasonic dental imaging probe (1), typically comprising several transducers (4) arranged to operate as a transmitter and a receiver, and in particular arranged to transmit ultrasonic waves at a frequency of at least 10 MHz, and optionally several transducers (4) arranged to operate as a transmitter and a receiver and arranged to transmit ultrasonic waves at a frequency of less than 4 MHz. The transducers are mounted on a flexible support (3), secured to a rigid frame (2) typically in a “U” shape. The invention also concerns a device comprising one such probe.
    Type: Application
    Filed: November 7, 2013
    Publication date: November 5, 2015
    Applicant: TROPHY
    Inventors: Jean-Pierre Gerbaulet, Jean-Marc Gregoire, Franck Levassort
  • Publication number: 20150209423
    Abstract: The present invention relates to the use of at least one attenuated measles virus for the manufacture of a medicament intended for treating malignant mesothelioma in an individual.
    Type: Application
    Filed: April 8, 2015
    Publication date: July 30, 2015
    Inventors: Anne Gauvrit, Frédéric Tangy, Marc Gregoire
  • Patent number: 9023643
    Abstract: The present invention relates to the use of at least one attenuated measles virus for the manufacture of a medicament intended for treating malignant mesothelioma in an individual.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: May 5, 2015
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Anne Gauvrit, Frédéric Tangy, Marc Gregoire
  • Publication number: 20140219925
    Abstract: Novel polymer nanovectors or particles and use thereof as medication and/or diagnostic agents.
    Type: Application
    Filed: June 28, 2012
    Publication date: August 7, 2014
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Philippe Bertrand, Regis Delatouche, Valerie Heroguez, Floraine Collette, Marc Gregoire, Christophe Blanquart, Fabien Gueugnon
  • Publication number: 20100278872
    Abstract: The present invention relates to the use of at least one attenuated measles virus for the manufacture of a medicament intended for treating malignant mesothelioma in an individual.
    Type: Application
    Filed: October 10, 2008
    Publication date: November 4, 2010
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCH MEDICALE (INSERM), INSTITUT PASTEUR
    Inventors: Anne Gauvrit, Frédéric Tangy, Marc Gregoire
  • Patent number: 6703016
    Abstract: The present invention relates to apoptotic bodies derived from human tumor cells or cell lines recovered from patient's tumor biopsy and induced to apoptotis, said apoptotic bodies having the following characteristics: they maintain plasma membrane integrity, they are vesicles above about 0,1 &mgr;m, they contain intact mitochondria and cleaved nuclear DNA originating from the tumor cells, they present unmasked tumor antigens on their membranes, they present specific tumor and MHC antigens from the patient. The invention also provides new monocytes derived cells, which can be used as anti-tumor vaccines after integration of apoptotic bodies. Apoptotic bodies are phagocytosed and processed by monocyte derived antigen presenting cells and potentiate the effective tumor antigenic presentation to the immune system.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: March 9, 2004
    Assignees: INSERM Institut National de la Sante et de la Recherche Medicale, IDM Immuno -Design Molecules
    Inventors: Marc Gregoire, Jacques Bartholeyns
  • Patent number: 6468220
    Abstract: A probe including a body having a main chamber receiving an assembly for transmitting and receiving an ultrasonic wave. The assembly is mounted on a frame driven in reciprocating motion by a driving motor. The chamber is closed by a probe tip having a slot made of a liquid impermeable solid element which is permeable to the acoustic wave transmitted by the acoustic transducer and toward the acoustic transducer. A reciprocating motion of the acoustic transducer is a translating movement parallel to the slot such that the ultrasonic beam is normal at the slot.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: October 22, 2002
    Assignee: Pierre Fabre Dermo-Cosmetique SA
    Inventors: Jack Elasri, Dany Carre, Frederic Peyre, Leandre Pourcelot, Jean-Marc Gregoire