Patents by Inventor Marc HEITZ

Marc HEITZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALTERNATIVE SURFACTANTS AS STABILIZERS FOR THERAPEUTIC PROTEIN FORMULATIONS
    Publication number: 20230346931
    Abstract: The present invention relates to novel liquid pharmaceutical compositions comprising proteins, preferably antibodies as defined herein together with one or more surfactants selected from TPGS, PVA, T1107, Px338, Px407, TMN-6, 15-S-15, Chol-PEG, and SL.
    Type: Application
    Filed: January 5, 2023
    Publication date: November 2, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Marc HEITZ, Tarik KHAN, Hannah Sophia KIENTZ, Claudia MUELLER, Janina Michelle PFAFF
  • STEREOSELECTIVE PH RESPONSIVE PEPTIDE DENDRIMERS FOR NUCLEIC ACID TRANSFECTION
    Publication number: 20220340899
    Abstract: The invention relates to stereoselective peptide dendrimers for nucleic acid transfection comprising the formula (D3)8-(B3-D2)4-(B2-D1)2-B1—Z (1), wherein Z is a hydrophobic core with Z being —XY1 (1a), —XY2XY2 (1b), —XY3Cys (1c) or —HP (1d), X is selected from Lys or Glu, and each Y is fatty or amine acids, HP is a hydrophobic peptide consisting of 3 to 5 hydrophobic amino, B is Lys and each D independently from any other D is a dipeptide consisting of one hydrophobic amino acid and one cationic amino acid (HC or CH), a dipeptide consisting of two cationic amino acids (CC) or a dipeptide consisting of two hydrophobic amino acids (HH). The invention further comprises a method for transfecting a cell (ex vivo) using the above-mentioned dendrimer.
    Type: Application
    Filed: August 7, 2020
    Publication date: October 27, 2022
    Applicant: UNIVERSITÄT BERN
    Inventors: Jean-Louis REYMOND, Marc HEITZ, Tamis DARBRE, Susanna ZAMOLO