Patents by Inventor Marc-Henri LeBrun

Marc-Henri LeBrun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7955828
    Abstract: The invention relates to the use of methionine synthase inhibitors for the treatment of fungal diseases of crops. The invention further relates to methods for treatment of crops against fungal diseases comprising the application of a methionine synthase inhibitor also methods for the identification of novel fungicidal compounds comprising a step for identification of methionine synthase inhibitors.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: June 7, 2011
    Assignee: Bayer Cropscience AG
    Inventors: Michel Droux, Marc-Henri Lebrun
  • Publication number: 20100120029
    Abstract: The present invention is directed to polynucleotides encoding proteins Essential For the Growth (EFG) of filamentous fungi. The invention also deals with namely polypeptides encoded by said polynucleotides, screening assays for identifying compounds capable of inhibiting said EFG proteins activities, pharmaceutical or phytosanitary compositions comprising such compounds.
    Type: Application
    Filed: March 3, 2009
    Publication date: May 13, 2010
    Inventors: Marie-Claire Grosjean-Cournoyer, Christophe Didier D'Enfert, Arnaud Firon, Francois Villalba, Marc-Henri Lebrun, Roland Beffa
  • Patent number: 7566547
    Abstract: The invention concerns a novel nucleic acid fragment of the genome of rice pathogenic fungus Magnaporthe grisea comprising a gene coding for a protein (hereafter referred to as gene 763) whereof the presence and integrity are indispensable for pathogenesis of said fungus with respect to rice and barley. The invention also concerns the promoter of said gene, the gene coding for protein 763, protein 763 and uses thereof for identifying potential biological targets for novel fungicide molecules and for isolating genes coding for proteins controlling biochemical functions essential to the pathogenesis of the fungus Magnaporthe grisea with respect to rice and barley. The invention further concerns compounds inhibiting pathogenesis of fungi related to the expression of gene 763.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: July 28, 2009
    Assignee: Bayer CropScience S.A.
    Inventors: Marc-Henri LeBrun, Marie-Pascale Latorse
  • Patent number: 7393639
    Abstract: The invention concerns a new tool for efficient mutagenesis enabling the generation of a collection of mutants in fungi by random insertion of a characterised Fusarium oxysporum Impala transposon in the genome of said fungi. The invention also concerns the resulting mutants.
    Type: Grant
    Filed: July 8, 2003
    Date of Patent: July 1, 2008
    Assignee: Bayer CropScience S.A.
    Inventors: Marie-Claire Grosjean-Cournoyer, Francois Villalba, Marc-Henri Lebrun, Marie-Josee Daboussi
  • Publication number: 20080132586
    Abstract: The invention relates to the use of methionine synthase inhibitors for the treatment of fungal diseases of crops. The invention further relates to methods for treatment of crops against fungal diseases comprising the application of a methionine synthase inhibitor also methods for the identification of novel fungicidal compounds comprising a step for identification of methionine synthase inhibitors.
    Type: Application
    Filed: December 20, 2005
    Publication date: June 5, 2008
    Inventors: Michel Droux, Marc-Henri Lebrun
  • Publication number: 20070129337
    Abstract: The invention concerns the use of ketol-acid reductoisomerase inhibitors for treating fungal diseases affecting crops. The invention concerns methods for treating crops against fungal diseases comprising applying a ketol-acid reductoisomerase inhibitor. The invention also concerns methods for identifying novel fungicidal compounds comprising a step which consists in identifying ketol-acid reductoisomerase inhibitors.
    Type: Application
    Filed: January 16, 2007
    Publication date: June 7, 2007
    Inventors: Renaud Dumas, Marc-Henri Lebrun, Jean-Luc Zundel, Geraldine Effantin, Valerie Morin
  • Publication number: 20070122868
    Abstract: The invention concerns a novel nucleic acid fragment of the genome of rice pathogenic fungus Magnaporthe grisea comprising a gene coding for a protein (hereafter referred to as gene 763) whereof the presence and integrity are indispensable for pathogenesis of said fungus with respect to rice and barley. The invention also concerns the promoter of said gene, the gene coding for protein 763, protein 763 and uses thereof for identifying potential biological targets for novel fungicide molecules and for isolating genes coding for proteins controlling biochemical functions essential to the pathogenesis of the fungus Magnaporthe grisea with respect to rice and barley. The invention further concerns compounds inhibiting pathogenesis of fungi related to the expression of gene 763.
    Type: Application
    Filed: November 7, 2005
    Publication date: May 31, 2007
    Applicant: Bayer CropScience S.A.
    Inventors: Marc-Henri LeBrun, Marie-Pascale Latorse
  • Patent number: 7166706
    Abstract: The invention concerns the use of ketol-acid reductoisomerase inhibitors for treating fungal diseases affecting crops. The invention concerns methods for treating crops against fungal diseases comprising applying a ketol-acid reductoisomerase inhibitor. The invention also concerns methods for identifying novel fungicidal compounds comprising a step which consists in identifying ketol-acid reductoisomerase inhibitors.
    Type: Grant
    Filed: March 10, 2004
    Date of Patent: January 23, 2007
    Assignee: Bayer Cropscience S.A.
    Inventors: Renaud Dumas, Marc-Henri Lebrun, Jean-Luc Zundel, Géraldine Effantin, Valérie Morin
  • Publication number: 20060235200
    Abstract: The present invention is directed to polynucleotides encoding proteins Essential For the Growth (EFG) of filaments fungi. The invention also deals with namely polypeptides encoded by said polynuctleotides, screening assays for identifying compounds capable of inhibiting said EFG proteins activities pharmaceutical or phytosanitary compositions comprising such compounds.
    Type: Application
    Filed: March 13, 2003
    Publication date: October 19, 2006
    Inventors: Marie-Clair Grosjean-Cournoyer, Christ D'Enfert, Arnaud Firon, Marc-Henri Lebrun, Roland Beffa
  • Patent number: 7070981
    Abstract: The invention concerns a novel nucleic acid fragment of the genome of rice pathogenic fungus Magnaporthe grisea comprising a gene coding for a protein (hereafter referred to as gene 763) whereof the presence and integrity are indispensable for pathogenesis of said fungus with respect to rice and barley. The invention also concerns the promoter of said gene, the gene coding for protein 763, protein 763 and uses thereof for identifying potential biological targets for novel fungicide molecules and for isolating genes coding for proteins controlling biochemical functions essential to the pathogenesis of the fungus Magnaporthe grisea with respect to rice and barley. The invention further concerns compounds inhibiting pathogenesis of fungi related to the expression of gene 763.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: July 4, 2006
    Assignee: Bayer CropScience S.A.
    Inventors: Marc-Henri LeBrun, Marie-Pascale Latorse
  • Publication number: 20050260759
    Abstract: The invention concerns a new tool for efficient mutagenesis enabling the generation of a collection of mutants in fungi by random insertion of a characterised Fusarium oxysporum Impala transposon in the genome of said fungi. The invention also concerns the resulting mutants.
    Type: Application
    Filed: July 8, 2003
    Publication date: November 24, 2005
    Inventors: Marie-Claire Grosjean-Cournoyer, Francois Villalba, Marc-Henri Lebrun, Marie-Josee Daboussi
  • Publication number: 20040259848
    Abstract: The invention concerns the use of ketol-acid reductoisomerase inhibitors for treating fungal diseases affecting crops. The invention concerns methods for treating crops against fungal diseases comprising applying a ketol-acid reductoisomerase inhibitor. The invention also concerns methods for identifying novel fungicidal compounds comprising a step which consists in identifying ketol-acid reductoisomerase inhibitors.
    Type: Application
    Filed: March 10, 2004
    Publication date: December 23, 2004
    Inventors: Renaud Dumas, Marc-Henri Lebrun, Jean-Luc Zundel, Geraldine Effantin, Valerie Morin
  • Publication number: 20040038359
    Abstract: The invention concerns a novel nucleic acid fragment of the genome of rice pathogenic fungus Magnaporthe grisea comprising a gene coding for a protein (hereafter referred to as gene 763) whereof the presence and integrity are indispensable for pathogenesis of said fungus with respect to rice and barley. The invention also concerns the promoter of said gene, the gene coding for protein 763, protein 763 and uses thereof for identifying potential biological targets for novel fungicide molecules and for isolating genes coding for proteins controlling biochemical functions essential to the pathogenesis of the fungus Magnaporthe grisea with respect to rice and barley. The invention further concerns compounds inhibiting pathogenesis of fungi related to the expression of gene 763.
    Type: Application
    Filed: April 14, 2003
    Publication date: February 26, 2004
    Inventors: Marc-Henri LeBrun, Marie-Pascale Latorse
  • Patent number: 6617163
    Abstract: The invention concerns a new tool for efficient mutagenesis enabling the generation of a collection of mutants in fungi by random insertion of a characterized Fusarium oxysporum Impala transposon in the genome of said fungi. The invention also concerns the resulting mutants.
    Type: Grant
    Filed: December 26, 2001
    Date of Patent: September 9, 2003
    Assignee: Aventis Cropscience S.A.
    Inventors: Marie-Claire Grosjean-Cournoyer, Francois Villalba, Marc-Henri Lebrun, Marie-Josee Daboussi