Patents by Inventor Marc Hoylaerts

Marc Hoylaerts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF PACAP SIGNALLING FOR THE PREVENTION AND TREATMENT OF THROMBOCYTOPENIA
    Publication number: 20100129372
    Abstract: The present invention discloses the use of inhibitors and/or antagonists of PACAP signalling for the manufacture of a medicament for the prevention or treatment of decreased blood platelet numbers (thrombocytopenia).
    Type: Application
    Filed: August 31, 2009
    Publication date: May 27, 2010
    Inventors: Kathleen Freson, Chris Van Geet, Marc Hoylaerts
  • ANTI-VPAC1 ANTIBODIES AND THEIR USES
    Publication number: 20100104530
    Abstract: Monoclonal antibodies, in particular monoclonal antibodies to the VPAC1 receptor protein, compositions containing them and nucleic acid sequences encoding them. Host cells expressing said monoclonal antibodies, recombinant (expression) vectors and methods for producing said antibodies. Prevention or treatment of thrombocytopenia with antibodies to the VPAC1 receptor.
    Type: Application
    Filed: June 26, 2008
    Publication date: April 29, 2010
    Inventors: Kathleen Freson, Chris Van Geet, Marc Hoylaerts, Jean-Marie Stassen
  • Inhibition of PACAP signalling for the prevention and treatment of thrombocytopenia
    Patent number: 7615219
    Abstract: The present invention discloses the use of inhibitors and/or antagonists of PACAP signalling for the manufacture of a medicament for the prevention or treatment of decreased blood platelet numbers (thrombocytopenia).
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: November 10, 2009
    Assignee: Life Sciences Research Partners VZW
    Inventors: Kathleen Freson, Chris Van Geet, Marc Hoylaerts
  • Polyhydroxy phenols and their use in binding p-selectin
    Publication number: 20060276545
    Abstract: Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, and a process for the preparation of gallic acid derivatives using a gallic-acid providing moiety are provided as well as polyhydroxy phenol-containing pharmaceutical and nutraceutical compositions. The use of polyhydroxy phenols as a medicament and especially for the manufacture of a medicament for the prevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used as targeting tools to P-selectin expressing cells or tissues in a composition, further comprising an active compound in a vehicle.
    Type: Application
    Filed: May 7, 2004
    Publication date: December 7, 2006
    Applicant: YAMANOUCHI PHARMACEUTICAL CO., LTD.
    Inventors: Erik Anna Biessen, Chantal Appeldoorn, Arnaud Bonnefoy, Theodorus Van Berkel, Johan Kuiper, Marc Hoylaerts
  • Inhibition of pacap signalling for the prevention and treatment of thrombocytopenia
    Publication number: 20060062785
    Abstract: The present invention discloses the use of inhibitors and/or antagonists of PACAP signalling for the manufacture of a medicament for the prevention or treatment of decreased blood platelet numbers (thrombocytopenia).
    Type: Application
    Filed: January 16, 2004
    Publication date: March 23, 2006
    Inventors: Kathleen Freson, Chris Van Geet, Marc Hoylaerts
  • Alpha-1-antiprotease purification
    Patent number: 4629567
    Abstract: Alpha-1-antiprotease is highly purified from an impure solution thereof by a series of chromtographic procedures.
    Type: Grant
    Filed: March 7, 1986
    Date of Patent: December 16, 1986
    Assignee: SmithKline-RIT
    Inventors: Alex J. Bollen, Paul Chuchana, Marc Hoylaerts