Patents by Inventor Marc Humbert

Marc Humbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dizocilpine derivatives as peripheral NMDA receptor antagonists
    Patent number: 11944616
    Abstract: The present invention relates to compounds of formula (I): for use as peripheral NMDA receptor antagonists.
    Type: Grant
    Filed: May 26, 2022
    Date of Patent: April 2, 2024
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ PARIS-SACLAY, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS (APHP), HOPITAL MARIE LANNELONGUE
    Inventors: Sylvia Cohen-Kaminsky, Marc Humbert, Sebastien Dumas, Gilles Bru-Mercier, Samir Messaoudi, Jean-Daniel Brion, Mouad Alami, Gilles Galvani
  • NOVEL DIZOCILPINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS
    Publication number: 20230285381
    Abstract: The present invention relates to compounds of formula (I); for use as peripheral NMDA receptor antagonists.
    Type: Application
    Filed: April 6, 2023
    Publication date: September 14, 2023
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ PARIS-SACLAY, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (APHP), HOPITAL MARIE LANNELONGUE
    Inventors: Sylvia COHEN-KAMINSKY, Marc HUMBERT, Sebastien DUMAS, Gilles BRU-MERCIER, Samir MESSAOUDI, Jean-Daniel BRION, Mouad ALAMI, Gilles GALVANI
  • NOVEL DIZOCILPINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS
    Publication number: 20220280498
    Abstract: The present invention relates to compounds of formula (I): for use as peripheral NMDA receptor antagonists.
    Type: Application
    Filed: May 26, 2022
    Publication date: September 8, 2022
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS SUD, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (APHP), HOPITAL MARIE LANNELONGUE
    Inventors: Sylvia COHEN-KAMINSKY, Marc HUMBERT, Sebastien DUMAS, Gilles BRU-MERCIER, Samir MESSAOUDI, Jean-Daniel BRION, Mouad ALAMI, Gilles GALVANI
  • Dizocilpine derivatives as peripheral NMDA receptor antagonists
    Patent number: 11376245
    Abstract: The present invention relates to compounds of formula (I) for use as peripheral NMDA receptor antagonists.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: July 5, 2022
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS SUD, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS (APHP), HOPITAL MARIE LANNELONGUE
    Inventors: Sylvia Cohen-Kaminsky, Marc Humbert, Sebastien Dumas, Gilles Bru-Mercier, Samir Messaoudi, Jean-Daniel Brion, Mouad Alami, Gilles Galvani
  • Adamantane and memantine derivatives as peripheral NMDA receptor antagonists
    Patent number: 10538482
    Abstract: The present invention relates to cationic compounds of formula (I) for use as peripheral NMDA receptor antagonists.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: January 21, 2020
    Assignees: Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance Publique-Hopitaux de Paris, Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud
    Inventors: Marc Humbert, Sylvia Cohen-Kaminsky, Sébastien Dumas, Gilles Bru-Mercier, Mouad Alami, Jean-Daniel Brion, Samir Messaoudi, Gilles Galvani
  • NOVEL DIZOCILPINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS
    Publication number: 20190307738
    Abstract: The present invention relates to compounds of formula (I) for use as peripheral NMDA receptor antagonists.
    Type: Application
    Filed: June 13, 2017
    Publication date: October 10, 2019
    Applicants: Institut National de la Sante et de la Recherche Medicale (Inserm), Centre National de la Recherche Scientifique (CNRS), Universite Paris SUD, Assistance Publique-Hopitaux de Paris (APHP), Hopital Marie Lannelongue
    Inventors: Sylvia COHEN-KAMINSKY, Marc HUMBERT, Sebastien DUMAS, Gilles BRU-MERCIER, Samir MESSAOUDI, Jean-Daniel BRION, Mouad ALAMI, Gilles GALVANI
  • NOVEL ADAMANTANE AND MEMANTINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS
    Publication number: 20180215699
    Abstract: The present invention relates to cationic compounds of formula (I) for use as peripheral NMDA receptor antagonists.
    Type: Application
    Filed: July 26, 2016
    Publication date: August 2, 2018
    Applicants: Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance Publique-Hôpitaux De Paris, Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud
    Inventors: Marc Humbert, Sylvia Cohen-Kaminsky, Sébastien Dumas, Gilles Bru-Mercier, Mouad Alami, Jean-Daniel Brion, Samir Messaoudi, Gilles Galvani
  • METHOD FOR THE DIAGNOSIS OF SYSTEMIC SCLERODERMA OR OF PULMONARY ARTERIAL HYPERTENSION
    Publication number: 20150323550
    Abstract: The invention relates to an in vitro method for detecting systemic scleroderma (SSc) and/or pulmonary arterial hypertension (PAH), or a risk of developing SSc or PAH, which comprises determining the presence and/or the amount of antibodies in a biological sample originating from a patient.
    Type: Application
    Filed: April 14, 2015
    Publication date: November 12, 2015
    Inventors: Luc MOUTHON, Marc HUMBERT, Cynthia CALZAS, Luc CAMOIN, Younes SAHBATOU
  • Method for diagnosing pulmonary artery hypertension
    Patent number: 8609356
    Abstract: The invention relates to an in vitro method for detecting pulmonary arterial hypertension (PAHT), or the risk of developing PAHT, which includes determining the presence and/or amount of anti-tenascin C antibodies in a biological sample from a patient.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: December 17, 2013
    Assignees: Assistance Publique-Hopitaux de Paris, Universite Paris Descartes, Universite Paris-Sud 11
    Inventors: Luc Mouthon, Marc Humbert, Mathieu Tamby
  • Method and device for reducing actual loads generated on airplane by an aerodynamic disturbance
    Patent number: 8374735
    Abstract: A method and device for reducing actual loads generated on airplane by an aerodynamic disturbance is provided, the device including means for determining a load exceeding envelope and means for determining deflection orders of airplane control surfaces to reduce loads applied on the latter, when the airplane flies inside the load exceeding envelope. More specifically, a flight envelope of the airplane is determined and used with theoretical loads applied to the aircraft to produce the load exceeding envelope based on couples of the flight envelope with theoretical loads that equal or exceed a load threshold.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: February 12, 2013
    Assignee: Airbus Operations (SAS)
    Inventors: Sébastien Blanc, Marc Humbert
  • METHOD FOR THE DIAGNOSIS OF SYSTEMIC SCLERODERMA OR OF PULMONARY ARTERIAL HYPERTENSION
    Publication number: 20110311995
    Abstract: The invention relates to an in vitro method for detecting systemic scleroderma (SSc) and/or pulmonary arterial hypertension (PAH), or a risk of developing SSc or PAH, which comprises determining the presence and/or the amount of antibodies in a biological sample originating from a patient.
    Type: Application
    Filed: September 17, 2009
    Publication date: December 22, 2011
    Inventors: Luc Mouthon, Marc Humbert, Cynthia Calzas, Luc Camoin, Younes Sahbatou
  • Method And Device For Reducing Actual Loads Generated On Airplane By An Aerodynamic Disturbance
    Publication number: 20110266399
    Abstract: According to the invention, the device (1) comprises means (3) for determining a load exceeding envelope and means (4, 5, 10) for determining deflection orders of airplane control surfaces (S1, S2, P1, P2) to reduce loads applied on the latter, when airplane (AC) flies inside said load exceeding envelope.
    Type: Application
    Filed: May 2, 2011
    Publication date: November 3, 2011
    Applicant: AIRBUS OPERATIONS (S.A.S.)
    Inventors: Sebastien Blanc, Marc Humbert
  • METHOD FOR DIAGNOSING PULMONARY ARTERY HYPERTENSION
    Publication number: 20110033876
    Abstract: The invention relates to an in vitro method for detecting pulmonary arterial hypertension (PAHT), or the risk of developing PAHT, which includes determining the presence and/or amount of anti-tenascin C antibodies in a biological sample from a patient.
    Type: Application
    Filed: April 10, 2009
    Publication date: February 10, 2011
    Applicant: UNIVERSITE PARIS-SUD 11
    Inventors: Luc Mouthon, Marc Humbert, Mathieu Tamby