Patents by Inventor Marc Labelle

Marc Labelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARYLSULFONES AND USES RELATED THERETO
    Publication number: 20080269283
    Abstract: Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:
    Type: Application
    Filed: June 27, 2008
    Publication date: October 30, 2008
    Inventors: Pingchen Fan, Hiroyuki Goto, Xiao He, Makoto Kukutani, Marc Labelle, Dustin L. McMinn, Jay P. Powers, Yosup Rew, Daqing Sun, Xuelei Yan
  • Arylsulfones and uses related thereto
    Patent number: 7402704
    Abstract: Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: July 22, 2008
    Assignee: Amgen Inc.
    Inventors: Pingchen Fan, Hiroyuki Goto, Xiao He, Makoto Kakutani, Marc Labelle, Dustin L. McMinn, Jay P. Powers, Yosup Rew, Daqing Sun, Xuelei Yan
  • Methods for treating atherosclerosis
    Publication number: 20080096900
    Abstract: The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, inflammation, thrombosis and other conditions and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
    Type: Application
    Filed: June 26, 2007
    Publication date: April 24, 2008
    Applicant: Amgen Inc.
    Inventors: Frank Kayser, Marc LaBelle, Bei Shan, Jian Zhang, Mingyue Zhou
  • Fused Bicyclic Nitrogen-Containing Heterocycles
    Publication number: 20070244096
    Abstract: Compounds, pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the activity of proteins involved in lipid metabolism and cell proliferation.
    Type: Application
    Filed: May 2, 2007
    Publication date: October 18, 2007
    Applicant: Japan Tobacco Inc.
    Inventors: Brian Fox, Noboru Furukawa, Xiaolin Hao, Kiyosei Iio, Takashi Inaba, Simon Jackson, Frank Kayser, Marc Labelle, Kexue Li, Takuya Matsui, Dustin McMinn, Nobuya Ogawa, Steven Rubenstein, Shoichi Sagawa, Kazuyuki Sugimoto, Masahiro Suzuki, Masahiro Tanaka, Guosen Ye, Atsuhito Yoshida, Jian Zhang
  • Fused bicyclic nitrogen-containing heterocycles
    Patent number: 7244727
    Abstract: Compounds, pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the activity of proteins involved in lipid metabolism and cell proliferation.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: July 17, 2007
    Assignee: Japan Tobacco Inc.
    Inventors: Brian M. Fox, Noboru Furukawa, Xiaolin Hao, Kiyosei Iio, Takashi Inaba, Simon M. Jackson, Frank Kayser, Marc Labelle, Kexue Li, Takuya Matsui, Dustin L. McMinn, Nobuya Ogawa, Steven M. Rubenstein, Shoichi Sagawa, Kazuyuki Sugimoto, Masahiro Suzuki, Masahiro Tanaka, Guosen Ye, Atsuhito Yoshida, Jian Zhang
  • Antiinflammation agents
    Publication number: 20070155777
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.
    Type: Application
    Filed: February 21, 2007
    Publication date: July 5, 2007
    Applicants: Tularik Inc.
    Inventors: Simon Burkitt, Mario Cardozo, Timothy Cushing, Michael DeGraffeneid, Christopher Farthing, Xiaolin Hao, Juan Jaen, Xian Jiao, David Kopecky, Marc Labelle, Sarah Lively, Dustin McMinn, Sven Rasmussen, Youngsook Shin, Andrew Smith, Marie-Louise Smith
  • Antiinflammation agents
    Publication number: 20070135464
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 14, 2007
    Inventors: Michelle Browner, David Clark, Timothy Cushing, Xiaolin Hao, Ronald Hawley, Xiao He, Juan Jaen, Sharada Labadie, Marie-Louise Smith, Francisco Talamas, Nigel Walker, Marc Labelle
  • Antiinflammation agents
    Patent number: 7199119
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: April 3, 2007
    Assignee: Amgen Inc.
    Inventors: Simon A. Burkitt, Mario G. Cardozo, Timothy D. Cushing, Michael R. DeGraffenreid, Christopher N. Farthing, Xiaolin Hao, Juan C. Jaen, XianYun Jiao, David J. Kopecky, Marc Labelle, Sarah E. Lively, Dustin L. McMinn, Sven P. Rasmussen, Youngsook Shin, Marie-Louise Smith, Andrew Smith
  • Antiinflammation agents
    Patent number: 7186841
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
    Type: Grant
    Filed: August 26, 2004
    Date of Patent: March 6, 2007
    Assignees: Amgen Inc., Syntex (U.S.A.) LLC
    Inventors: Michelle F. Browner, David L. Clark, Timothy D. Cushing, Xiaolin Hao, Ronald C. Hawley, Xiao He, Juan C. Jaen, Sharada S. Labadie, Marie-Louise Smith, Francisco X. Talamas, Nigel P. C. Walker, Marc Labelle
  • Inflammation modulators
    Patent number: 7176314
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain quinoline or quinazoline rings.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: February 13, 2007
    Assignee: Amgen, Inc.
    Inventors: Timothy D. Cushing, Xiao He, Marie-Louise Smith, Michael R. DeGraffenreid, Jay Powers, Craig S. Tomooka, David L. Clark, Xiaolin Hao, Juan C. Jaen, Marc Labelle, Nigel P. C. Walker, Adrian L. Gill, Francisco X. Talamas, Sharada Labadie
  • Arylsulfones and uses related thereto
    Publication number: 20050277665
    Abstract: Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:
    Type: Application
    Filed: April 14, 2005
    Publication date: December 15, 2005
    Inventors: Pingchen Fan, Hiroyuki Goto, Xiao He, Makoto Kakutani, Marc Labelle, Dustin McMinn, Jay Powers, Yosup Rew, Daqing Sun, Xuelei Yan
  • Antiinflammation agents
    Publication number: 20050043330
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
    Type: Application
    Filed: August 26, 2004
    Publication date: February 24, 2005
    Applicant: Amgen Inc.
    Inventors: Michelle Browner, David Clark, Timothy Cushing, Xiaolin Hao, Ronald Hawley, Xiao He, Juan Jaen, Sharada Labadie, Marie-Louise Smith, Francisco Talamas, Nigel Walker, Marc Labelle
  • Antiinflammation agents
    Patent number: 6846834
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: January 25, 2005
    Assignees: Amgen Inc., Syntex (U.S.A.) LLC
    Inventors: Michelle F. Browner, David L. Clark, Timothy D. Cushing, Xiaolin Hao, Ronald C. Hawley, Xiao He, Juan C. Jaen, Sharada S. Labadie, Marie-Louise Smith, Francisco X. Talamas, Nigel P. C. Walker, Marc Labelle
  • Fused bicyclic nitrogen-containing heterocycles
    Publication number: 20040209871
    Abstract: Compounds, pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the activity of proteins involved in lipid metabolism and cell proliferation.
    Type: Application
    Filed: November 21, 2003
    Publication date: October 21, 2004
    Applicants: Tularik Inc., Japan Tobacco Inc.
    Inventors: Brian M. Fox, Noboru Furukawa, Xiaolin Hao, Kiyosei Iio, Takashi Inaba, Simon M. Jackson, Frank Kayser, Marc Labelle, Kexue Li, Takuya Matsui, Dustin L. McMinn, Nobuya Ogawa, Steven M. Rubenstein, Shoichi Sagawa, Kazuyuki Sugimoto, Masahiro Suzuki, Masahiro Tanaka, Guosen Ye, Atsuhito Yoshida, Jian Zhang
  • Antiinflammation agents
    Publication number: 20040097485
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.
    Type: Application
    Filed: September 19, 2003
    Publication date: May 20, 2004
    Applicant: Tularik Inc.
    Inventors: Simon A. Burkitt, Mario G. Cardozo, Timothy D. Cushing, Michael R. DeGraffenreid, Christopher N. Farthing, Xiaolin Hao, Juan C. Jaen, Xian Yun Jiao, David J. Kopecky, Marc Labelle, Sarah E. Lively, Dustin L. McMinn, Sven P. Rasmussen, Youngsook Shin, Andrew Smith, Marie-Louise Smith
  • Method of treatment using phenyl and biaryl derivatives as prostaglandin E inhibitors and compounds useful therefore
    Patent number: 6627656
    Abstract: This invention encompasses a method for the treatment or prevention of prostaglandin mediated diseases comprising administering to a mammalian patient a compound of formula I: in an amount that is effective to treat or prevent said prostaglandin mediated disease. Novel compounds are also disclosed.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: September 30, 2003
    Inventors: Michel Gallant, Nicolas Lachance, Marc Labelle, Robert Zamboni, Helene Juteau, Yves Gareau, Patrick Lacombe
  • Inflammation modulators
    Publication number: 20030181472
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain quinoline or quinazoline rings.
    Type: Application
    Filed: December 4, 2002
    Publication date: September 25, 2003
    Applicant: Tularik Inc.
    Inventors: David L. Clark, Timothy D. Cushing, Michael R. DeGraffenreid, Xiaolin Hao, Xiao He, Juan C. Jaen, Marc Labelle, Jay Powers, Marie-Louise Smith, Craig S. Tomooka, Nigel P.C. Walker, Adrian L. Gill, Francisco X. Talamas, Sharada Labadie
  • Combination product and methods of use
    Publication number: 20030130333
    Abstract: A pharmaceutical composition is disclosed which is comprised of an E-type prostaglandin ligand and a COX-2 selective inhibiting compound, in combination with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 26, 2002
    Publication date: July 10, 2003
    Inventors: Chi Chung Chan, Marc Labelle, Kathleen Metters
  • Methods for inhibiting bone resorption
    Patent number: 6586457
    Abstract: The present invention relates to methods for inhibiting bone resorption in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of an EP4 receptor subtype antagonist.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: July 1, 2003
    Assignees: Merck & Co., Inc., Merck Frosst Canada & Co.
    Inventors: Shun-Ichi Harada, Mohamed MacHwate, Gideon A. Rodan, Marc Labelle, Kathleen Metters, Robert N. Young
  • Antiinflammation agents
    Publication number: 20020161004
    Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.
    Type: Application
    Filed: October 23, 2001
    Publication date: October 31, 2002
    Applicant: Syntex (U.S.A.) LLC
    Inventors: Michelle F. Browner, David L. Clark, Timothy D. Cushing, Xiaolin Hao, Ronald C. Hawley, Xiao He, Juan C. Jaen, Sharada S. Labadie, Marie-Louise Smith, Francisco X. Talamas, Nigel P.C. Walker, Marc Labelle