Patents by Inventor Marc Lecomte

Marc Lecomte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Specific caspase-10 inhibitors
    Patent number: 8357721
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: January 22, 2013
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • Methods of treating diabetic retinopathy with pericyte apoptosis inhibitors
    Patent number: 8119609
    Abstract: A method of preventing or treating diabetic retinopathy is disclosed including administering to a mammal a therapeutically effective amount of an inhibitor of retinal pericyte apoptosis. Also disclosed is a pharmaceutical composition which treats and/or prevents diabetic retinopathy comprising as an active agent a therapeutically effective amount of at least one inhibitor of retinal pericyte apoptosis and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: February 21, 2012
    Assignees: Merck Sante, INSERM
    Inventors: Marc Lecomte, Ulriche Denis, Clarisse Paget, Nicolas Wiernsperger, Michel Lagarde
  • Specific caspase-10 inhibitors
    Patent number: 7829721
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 9, 2010
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stéphane Yvon, Marie Noelle Denuault, Denis Descours
  • Novel Specific Caspase-10 Inhibitors
    Publication number: 20080255173
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: November 2, 2005
    Publication date: October 16, 2008
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stephane Yvon, Marie Noelle Denuault, Denis Descours
  • Novel Specific Caspase-10 Inhibitors
    Publication number: 20080182906
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: April 6, 2006
    Publication date: July 31, 2008
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • Methods and compositions of treating and/or preventing diabetic retinopathy with pericyte apoptosis inhibitors
    Publication number: 20030216290
    Abstract: A method of preventing or treating diabetic retinopathy is disclosed including administering to a mammal a therapeutically effective amount of an inhibitor of retinal pericyte apoptosis. Also disclosed is a pharmaceutical composition which treats and/or prevents diabetic retinopathy comprising as an active agent a therapeutically effective amount of at least one inhibitor of retinal pericyte apoptosis and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 23, 2003
    Publication date: November 20, 2003
    Applicants: Merck Sante, a corporation of France, INSERM, a corporation of France
    Inventors: Marc Lecomte, Ulriche Denis, Clarisse Paget, Nicolas Wiernsperger, Michel Lagarde
  • Linear precision guide
    Patent number: 4983049
    Abstract: A linear precision guide comprises a guide rail (1) having an outer profile of a prismatic shape inscribed in a circle and exhibiting three arcs (3, 4). The arcs (4) are equal and their successive extremities (5) are connected by a lower plane side-face (6). The four other extremities (8) of the arcs are connected by two recessed plane sides (9). Each of the recessed plane sides comprises outer connections in the form of circular rail recesses (10). Said recessed sides and recesses serve, following precision-grinding, for races of sets of movable balls (19, 19a) supported on the wings (17) of the block (14) enclosing the rail (1) supported on the grooves and ducts (18, 21). The sets of balls (19, 19a) are supported by means of a lower housing (25) and of a tongue (32). Said housing (25) is provided with inner circular grooves (29) allowing the recirculation of the lower balls (19) during the displacement of the block (14).
    Type: Grant
    Filed: January 25, 1990
    Date of Patent: January 8, 1991
    Inventor: Marc Lecomte