Patents by Inventor Marc Lim
Marc Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12136387Abstract: An electronic device may include processing circuitry configured to generate a first frame of image content and a second frame of image content. The second frame of image content is different from the first frame of image content. The electronic device may also include a display configured to display the first frame of image content at a first refresh rate. In response to receiving the second frame of image content, the electronic device may initially increase the refresh rate before tapering back to the first refresh rate while displaying the second frame of image content.Type: GrantFiled: July 19, 2023Date of Patent: November 5, 2024Assignee: Apple Inc.Inventors: Jie Won Ryu, Ing-Jye Wang, Alex H Pai, Alexandre V Gauthier, Ardra Singh, Arthur L Spence, Gihoon Choo, Hyunsoo Kim, Hyunwoo Nho, Jenny Hu, Graeme M Williams, Jongyup Lim, Kingsuk Brahma, Marc J DeVincentis, Peter F Holland, Shawn P Hurley
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Publication number: 20240067964Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: ApplicationFiled: February 28, 2023Publication date: February 29, 2024Applicant: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Patent number: 11859180Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: GrantFiled: June 9, 2020Date of Patent: January 2, 2024Assignee: Ionis Pharmaceuticals, Inc.Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Patent number: 11634711Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: GrantFiled: August 3, 2020Date of Patent: April 25, 2023Assignee: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Publication number: 20210079391Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: ApplicationFiled: June 9, 2020Publication date: March 18, 2021Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Publication number: 20210002643Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: ApplicationFiled: August 3, 2020Publication date: January 7, 2021Applicant: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Publication number: 20200276224Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: ApplicationFiled: October 9, 2019Publication date: September 3, 2020Applicant: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Patent number: 10478448Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: GrantFiled: December 27, 2017Date of Patent: November 19, 2019Assignee: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Publication number: 20190316123Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: ApplicationFiled: November 28, 2018Publication date: October 17, 2019Applicant: Ionis Pharmaceuticals, Inc.Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Patent number: 10231816Abstract: Medical devices, systems, methods, and kits for the medialization of a vocal cord are described. A method comprises creating a passageway in thyroid cartilage of a patient, advancing a light source through the passageway, activating the light source, viewing light emitted from the light source to confirm placement of the passageway relative to the vocal cord, and advancing a medical device through the passageway to move the vocal cord toward a midline of the larynx of the patient.Type: GrantFiled: April 7, 2017Date of Patent: March 19, 2019Assignees: Cook Medical Technologies LLC, Northwestern UniversityInventors: Pamela Ridgley, Darin Schaeffer, Gordon Siegel, Marc Lim
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Patent number: 10174318Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: GrantFiled: October 14, 2016Date of Patent: January 8, 2019Assignee: Ionis Pharmaceuticals, Inc.Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Publication number: 20180256629Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: ApplicationFiled: December 27, 2017Publication date: September 13, 2018Applicant: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Patent number: 9884072Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: GrantFiled: January 9, 2017Date of Patent: February 6, 2018Assignee: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Publication number: 20170211062Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: ApplicationFiled: October 14, 2016Publication date: July 27, 2017Applicant: Ionis Pharmaceuticals, Inc.Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Publication number: 20170209252Abstract: Medical devices, systems, methods, and kits for the medialization of a vocal cord are described. A method comprises creating a passageway in thyroid cartilage of a patient, advancing a light source through the passageway, activating the light source, viewing light emitted from the light source to confirm placement of the passageway relative to the vocal cord, and advancing a medical device through the passageway to move the vocal cord toward a midline of the larynx of the patient.Type: ApplicationFiled: April 7, 2017Publication date: July 27, 2017Applicants: Cook Medical Technologies LLC, Northwestern UniversityInventors: Pamela Ridgley, Darin Schaeffer, Gordon Siegel, Marc Lim
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Publication number: 20170182084Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: ApplicationFiled: January 9, 2017Publication date: June 29, 2017Applicant: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Patent number: 9615918Abstract: Medical devices, systems, methods, and kits for the medialization of a vocal cord are described. An embodiment of a medical device comprises a proximal portion, a distal portion, and an elongate body extending from the proximal portion to the distal portion. The elongate body defines a thread extending from the proximal portion and the distal portion.Type: GrantFiled: August 31, 2015Date of Patent: April 11, 2017Assignees: COOK MEDICAL TECHNOLOGIES LLC, NORTHWESTERN UNIVERSITYInventors: Pamela Ridgley, Darin Schaeffer, Gordon Siegel, Marc Lim
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Patent number: 9574193Abstract: Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.Type: GrantFiled: November 24, 2014Date of Patent: February 21, 2017Assignee: Ionis Pharmaceuticals, Inc.Inventors: Rosanne M. Crooke, Mark J. Graham, Susan M. Freier, Marc Lim, Andrew Dibble
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Publication number: 20160002624Abstract: The present disclosure provides compositions comprising an antisense oligonucleotide and one or more excipients that modulates viscosity, turbidity or both viscosity and turbidity. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity are provided. In certain embodiments, compositions comprising an antisense oligonucleotide and one or more excipients having low turbidity are provided. In certain embodiments, pharmaceutical compositions comprising an antisense oligonucleotide and one or more excipients having low viscosity and turbidity are provided.Type: ApplicationFiled: May 17, 2013Publication date: January 7, 2016Applicant: ISIS PHARMACEUTICALS, INC.Inventors: Andrew Dibble, Lloyd Tillman, Bret Coldren, Marc Lim
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Publication number: 20150366662Abstract: Medical devices, systems, methods, and kits for the medialization of a vocal cord are described. An embodiment of a medical device comprises a proximal portion, a distal portion, and an elongate body extending from the proximal portion to the distal portion. The elongate body defines a thread extending from the proximal portion and the distal portion.Type: ApplicationFiled: August 31, 2015Publication date: December 24, 2015Applicants: NORTHWESTERN UNIVERSITY, COOK MEDICAL TECHNOLOGIES LLCInventors: Pamela Ridgley, Darin Schaeffer, Gordon Siegel, Marc Lim