Patents by Inventor Marc Madou

Marc Madou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10894254
    Abstract: A portable pathogen analysis system (PPAS) designed to detect microbial pathogens at the point-of-sample collection. The system comprises a concentration tube used for the concentration of microbes in large volumes of water samples using super absorbent polymer (SAP) beads and a hand-powered centrifuge; and a processing component, which functions as a portable lab-on-a-disc droplet digital nucleic acid amplification system, which integrates DNA extraction, nucleic acid amplification, and post-amplicon analysis in a single unit. The present invention provides a fast, cost-effective, and user-friendly solution for microbial water quality analysis in low-resource settings.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: January 19, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Sunny Jiang, Hamsa Gowda, Xiao Huang, Xunyi Wu, Marc Madou, Michael R. Hoffmann
  • Publication number: 20200407880
    Abstract: Systems and methods are provided for fabricating carbon nanostructures by low voltage near-field electromechanical spinning (LV-NFEMS). Processes described herein can produce ˜2-5 nm carbon nanowires with ultrahigh electrical conductivity using top-down and controlled reductive techniques from a polymer. Configurations are also provided to allow for deposition control and fiber elongation/alignment. One embodiment uses a low voltage near-field electromechanical spinning process to produce a polymer fiber from a polymer solution. Another embodiment of the method uses pyrolysis to convert the produced polymer fiber into a ˜2-5 nm carbon nanowire. System configurations provide advancements in polymer droplet control and control of a sustained jet of polymer solution with the use low voltages. Systems and processes described herein can include use of an array of polymer precursor nanofibers suspended onto a silicon substrate and converted to carbon nanowires.
    Type: Application
    Filed: June 29, 2020
    Publication date: December 31, 2020
    Applicant: The Regents of the University of California
    Inventors: Marc MADOU, Jufeng DENG, Alexander HWU, Xingxu YAN
  • Publication number: 20200376452
    Abstract: There is described a system for growing a microorganism in liquid culture, the system comprising: a driving apparatus configured to house and oscillate a microfluidic cartridge; and a microfluidic cartridge comprising at least one incubation chamber, such that when the system is in use, the incubation chamber may be oscillated back and forth along an oscillation path using a preferred oscillation protocol. There is also described a method of growing a microorganism in liquid culture, the method comprising disposing a microorganism and suitable growth medium into an incubation chamber; and mixing the microorganism and growth medium by oscillating the incubation chamber back and forth along an oscillation path using a preferred oscillation protocol. There is also described a microfluidic cartridge that may be used to grow microorganisms using the system and methods described above.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 3, 2020
    Inventors: Alexandra Perebikovsky, Bernard Churchill, Scott Churchman, David Arnold Haake, Colin Wynn Halford, Yujia Liu, Marc Madou, Gabriel Monti
  • Publication number: 20200370036
    Abstract: There is described a method for extracting a target chemical compound from a cellular material in a sample. The method comprising the steps of: subjecting the sample to mechanical lysis to cause disruption of a cellular membrane in the cellular material; contacting the sample with an alkaline material to produce a lysate composition comprising the target chemical compound; and recovering the lysate composition from the sample. There is also described a method for producing a lysate composition comprising RNA from a mammalian bodily fluid sample comprising a cellular material. There is also described a method for extracting a nucleic acid from a cellular material in a bodily fluid or an inoculant derived therefrom.
    Type: Application
    Filed: August 3, 2018
    Publication date: November 26, 2020
    Inventors: Gabriel MONTI, Colin Wynn HALFORD, Alexandra PEREBIKOVSKY, Yujia LIU, Horacio KIDO, David Arnold HAAKE, Marc MADOU, Daniel GUSSIN, Bernard CHURCHILL
  • Publication number: 20190105653
    Abstract: A portable pathogen analysis system (PPAS) designed to detect microbial pathogens at the point-of-sample collection. The system comprises a concentration tube used for the concentration of microbes in large volumes of water samples using super absorbent polymer (SAP) beads and a hand-powered centrifuge; and a processing component, which functions as a portable lab-on-a-disc droplet digital nucleic acid amplification system, which integrates DNA extraction, nucleic acid amplification, and post-amplicon analysis in a single unit. The present invention provides a fast, cost-effective, and user-friendly solution for microbial water quality analysis in low-resource settings.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 11, 2019
    Inventors: Sunny Jiang, Hamsa Gowda, Xiao Huang, Xunyi Wu, Marc Madou, Michael R. Hoffmann
  • Publication number: 20170052162
    Abstract: Disclosed herein are devices comprising a solid state gas sensor comprising a catalyst and a detection component capable of sensing halogenated gases through an increase or decrease in electrical conductivity. Further disclosed herein are methods of detecting one or more halogenated organic compounds, comprising providing a device comprising a solid state gas sensor comprising a catalyst and a detection component capable of sensing halogenated gases through an increase or decrease in electrical conductivity, and using the device to detect one or more small solid state halogenated organic compounds. Also disclosed herein are various methods of treating asthma in an individual.
    Type: Application
    Filed: August 19, 2016
    Publication date: February 23, 2017
    Applicant: The Regents of the University of California
    Inventors: Hye-Won Shin, Marc Madou, Dan M. Cooper, Donald R. Blake
  • Patent number: 9453839
    Abstract: A microfluidic device, a microfluidic system and a method for controlling a microfluidic test device are provided.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: September 27, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kameel Abi-Samra, Marc Madou, Tae Hyeong Kim, Yoon-Kyoung Cho
  • Patent number: 9186672
    Abstract: A CD-based device for separating plasma from whole blood includes a substrate, a sedimentation chamber disposed in the substrate, and a collection chamber disposed in the substrate and in fluidic communication with the sedimentation chamber through a siphon channel. The sedimentation chamber includes a plurality of finger-like structures disposed along a radially outward edge of the sedimentation chamber, and protruding radially inward relative to the axis of rotation of the substrate. A method for separating plasma from whole blood using the CD-based device includes introducing a blood sample into the sedimentation chamber, rotating the substrate about an axis of rotation at a first rotational speed to separate the plasma from blood cells, and rotating the substrate about the axis of rotation at a second rotational speed, which is lower than the first rotational speed, to move the plasma from the sedimentation chamber into the collection chamber.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: November 17, 2015
    Assignee: THE REGENTS OF THE UNIVERISTY OF CALIFORNIA
    Inventors: Mary Amasia, Marc Madou
  • Patent number: 9040809
    Abstract: A nano power cell and method of use are described wherein the nano power cell absorbs electromagnetic energy is nano particles in an optical fluid that flow in microchannels of the nano power cell.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: May 26, 2015
    Assignee: SOLERA LABORATORIES, INC.
    Inventors: Saad Al Kenany, Marc Madou
  • Publication number: 20140120521
    Abstract: A microfluidic device, a microfluidic system and a method for controlling a microfluidic test device are provided.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 1, 2014
    Applicants: ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY, SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kameel ABI-SAMRA, Marc MADOU, Tae Hyeong KIM, Yoon-Kyoung CHO
  • Patent number: 8586148
    Abstract: An electrospinning method includes providing a nozzle fluidically coupled to a source of polymer ink and providing a substrate adjacent to the nozzle. A first voltage is applied to the nozzle to initiate electrospinning of the polymer ink onto the substrate, wherein the first voltage is within the range of about 400V to about 1000V. The voltage is then reduced to a second, lower voltage wherein the voltage is within the range of about 600V to about 150V.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: November 19, 2013
    Assignee: The Regents of the University of California
    Inventors: Gobind S. Bisht, Giulia Canton, Marc Madou, Alireza Mirsepassi, Derek Dunn-Rankin
  • Patent number: 8534319
    Abstract: Methods and devices using a co-radial arrangement of serial siphon structures composed of siphon valves each separated by a capillary valve to save radial space in a fluidic system. Such serial siphon valves allow to sequentially distribute liquids in a fluidic system upon application of successive centripetal accelerations and decelerations applied to a rotary platform.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: September 17, 2013
    Assignees: Universite Laval, The Regents of the University of California
    Inventors: Michel G. Bergeron, Regis Peytavi, Horacio Kido, Marc Madou
  • Publication number: 20130081672
    Abstract: A nano power cell and method of use are described wherein the nano power cell absorbs electromagnetic energy is nano particles in an optical fluid that flow in microchannels of the nano power cell.
    Type: Application
    Filed: November 26, 2012
    Publication date: April 4, 2013
    Inventors: Saad Al Kenany, Marc Madou
  • Patent number: 8319092
    Abstract: A nano power cell and method of use are described wherein the nano power cell absorbs electromagnetic energy is nano particles in an optical fluid that flow in microchannels of the nano power cell.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: November 27, 2012
    Assignee: Solera Laboratories, Inc.
    Inventors: Saad Al Kenany, Marc Madou
  • Publication number: 20120295781
    Abstract: A CD-based device for separating plasma from whole blood includes a substrate, a sedimentation chamber disposed in the substrate, and a collection chamber disposed in the substrate and in fluidic communication with the sedimentation chamber through a siphon channel. The sedimentation chamber includes a plurality of finger-like structures disposed along a radially outward edge of the sedimentation chamber, and protruding radially inward relative to the axis of rotation of the substrate. A method for separating plasma from whole blood using the CD-based device includes introducing a blood sample into the sedimentation chamber, rotating the substrate about an axis of rotation at a first rotational speed to separate the plasma from blood cells, and rotating the substrate about the axis of rotation at a second rotational speed, which is lower than the first rotational speed, to move the plasma from the sedimentation chamber into the collection chamber.
    Type: Application
    Filed: April 17, 2012
    Publication date: November 22, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Mary Amasia, Marc Madou
  • Patent number: 8303911
    Abstract: A microfluidic system for processing a sample includes a microfluidic CD in the form a rotatable disc, the disc containing a plurality of separate lysis chambers therein. A magnetic lysis blade and lysis beads are disposed in each of the lysis chambers and a plurality of stationary magnets are disposed adjacent to and separate from the microfluidic CD. The stationary magnets are configured to magnetically interact with each of the magnetic lysis blades upon rotation of the microfluidic CD. Each lysis chamber may have its own separate sample inlet port or, alternatively, the lysis chambers may be connected to one another with a single inlet port coupled to one of the lysis chambers. Downstream processing may include nucleic acid amplification using thermoelectric heating as well as detection using a nucleic acid microarray.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: November 6, 2012
    Assignee: The Regents of the University of California
    Inventors: Jonathan P. Siegrist, Robert A. Gorkin, III, Regis Peytavi, Marc Madou, Horacio Kido, Mary Amasia, Emmanuel Roy, Teodor Veres
  • Publication number: 20120244291
    Abstract: An electrospinning method includes providing a nozzle fluidically coupled to a source of polymer ink and providing a substrate adjacent to the nozzle. A first voltage is applied to the nozzle to initiate electrospinning of the polymer ink onto the substrate, wherein the first voltage is within the range of about 400V to about 1000V. The voltage is then reduced to a second, lower voltage wherein the voltage is within the range of about 600V to about 150V.
    Type: Application
    Filed: March 8, 2012
    Publication date: September 27, 2012
    Inventors: Gobind S. Bisht, Giulia Canton, Marc Madou, Alireza Mirsepassi, Derek Dunn-Rankin
  • Publication number: 20120125071
    Abstract: Novel molds and methods for Bulk Metallic Glass (BMG) molding using carbon templates obtained from pyrolyzed materials are provided. The method employs the Carbon MEMS (C-MEMS) technique to derive molds of different geometries and dimensions. The resultant carbon structures are stable at very high temperatures and have sufficient mechanical strength to be used as master molds for the thermoplastic forming of BMGs.
    Type: Application
    Filed: March 29, 2010
    Publication date: May 24, 2012
    Inventors: Jan Schroers, Golden Kumar, Marc Madou, Rodrigo Martinez-Duarte
  • Publication number: 20110111987
    Abstract: A microfluidic system for processing a sample includes a microfluidic CD in the form a rotatable disc, the disc containing a plurality of separate lysis chambers therein. A magnetic lysis blade and lysis beads are disposed in each of the lysis chambers and a plurality of stationary magnets are disposed adjacent to and separate from the microfluidic CD. The stationary magnets are configured to magnetically interact with each of the magnetic lysis blades upon rotation of the microfluidic CD. Each lysis chamber may have its own separate sample inlet port or, alternatively, the lysis chambers may be connected to one another with a single inlet port coupled to one of the lysis chambers. Downstream processing may include nucleic acid amplification using thermoelectric heating as well as detection using a nucleic acid microarray.
    Type: Application
    Filed: October 14, 2010
    Publication date: May 12, 2011
    Inventors: Jonathan Siegrist, Robert A. Gorkin, III, Regis Peytavi, Marc Madou, Horacio Kido, Mary Amasia, Emmanuel Roy, Teodor Veres
  • Publication number: 20110094600
    Abstract: Methods and devices using a co-radial arrangement of serial siphon structures composed of siphon valves each separated by a capillary valve to save radial space in a fluidic system. Such serial siphon valves allow to sequentially distribute liquids in a fluidic system upon application of successive centripetal accelerations and decelerations applied to a rotary platform.
    Type: Application
    Filed: March 3, 2008
    Publication date: April 28, 2011
    Inventors: Michel G. Bergeron, Regis Peytavi, Horacio Kido, Marc Madou