Patents by Inventor Marc Marino

Marc Marino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
    Patent number: 10022450
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: July 17, 2018
    Assignees: Wisconsin Alumni Research Foundation, The Regents of the University of California
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • Automated scratch detection system and signal processing algorithm for the study of pruritus in animals
    Patent number: 9770195
    Abstract: The invention provides a method for automated assessment of pruritus comprising detecting movement of a band located on a limb of a subject animal so as to obtain a signal associated with the detection movement, processing the signal associated with the detected movement through an algorithm configured to establish a scratch movement trigger, and translating the processed signal into scratch counts.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: September 26, 2017
    Assignee: The Regents of the University of California
    Inventors: Tony L. Yaksh, Shelle Malkmus, Marc Marino
  • Regulation of Specific Spinal Neurons Regulating Pain Transmission
    Publication number: 20160361429
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Application
    Filed: August 19, 2016
    Publication date: December 15, 2016
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
    Patent number: 9447405
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: September 20, 2016
    Assignees: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • Regulation of Specific Spinal Neurons Regulating Pain Transmission
    Publication number: 20140255376
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Application
    Filed: February 14, 2014
    Publication date: September 11, 2014
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • AUTOMATED SCRATCH DETECTION SYSTEM AND SIGNAL PROCESSING ALGORITHM FOR THE STUDY OF PRURITUS IN ANIMALS
    Publication number: 20140046222
    Abstract: The invention provides a method for automated assessment of pruritus comprising detecting movement of a band located on a limb of a subject animal so as to obtain a signal associated with the detection movement, processing the signal associated with the detected movement through an algorithm configured to establish a scratch movement trigger, and translating the processed signal into scratch counts.
    Type: Application
    Filed: August 9, 2013
    Publication date: February 13, 2014
    Inventors: Tony L. Yaksh, Shelle Malkmus, Marc Marino, James Skahen