Patents by Inventor Marc Pascal

Marc Pascal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylaminothiazole derivatives and use thereof as beta-amyloid inhibitors
    Patent number: 7759377
    Abstract: Compounds of formula (I) as defined herein: inhibit the formation of the ?-amyloid peptide (?-A4) and are, therefore, useful in the treatment of pathologies in which a ?-amyloid peptide (?-A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: July 20, 2010
    Assignee: Sanofi-Aventis
    Inventors: Sylvie Baltzer, Marc Pascal, Viviane Van Dorsselaer
  • ACYLAMINOTHIAZOLE DERIVATIVES AND USE THEREOF AS BETA-AMYLOID INHIBITORS
    Publication number: 20080176911
    Abstract: Compounds of formula (I) as defined herein: inhibit the formation of the ?-amyloid peptide (?-A4) and are, therefore, useful in the treatment of pathologies in which a ?-amyloid peptide (?-A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.
    Type: Application
    Filed: March 20, 2008
    Publication date: July 24, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Sylvie BALTZER, Marc PASCAL, Viviane VAN DORSSELAER
  • Acylaminothiazole derivatives and use thereof as ?-amyloid inhibitors
    Patent number: 7371770
    Abstract: Compounds of formula (I) as defined herein: inhibit the formation of the ?-amyloid peptide (?-A4) and are, therefore, useful in the treatment of pathologies in which a ?-amyloid peptide (?-A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: May 13, 2008
    Assignee: Sanofiaventis
    Inventors: Sylvie Baltzer, Marc Pascal, Viviane Van Dorsselaer
  • ACYLAMINOTHIAZOLE DERIVATIVES AND USE THEREOF AS BETA-AMYLOID INHIBITORS
    Publication number: 20060293366
    Abstract: Compounds of formula (I) as defined herein: inhibit the formation of the ?-amyloid peptide (?-A4) and are, therefore, useful in the treatment of pathologies in which a ?-amyloid peptide (?-A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.
    Type: Application
    Filed: July 14, 2006
    Publication date: December 28, 2006
    Applicant: SANOFI-AVENTIS
    Inventors: Sylvie Baltzer, Marc Pascal, Viviane Van Dorsselaer
  • SACCHARIN DERIVATIVES AS ORALLY ACTIVE ELASTASE INHIBITORS
    Publication number: 20030114449
    Abstract: Orally active compounds of general formula (I) wherein R1 is methyl, ethyl or 2-morpholino-ethyl group, R2 is piperidino, morpholino or 4-methyl-piperazinyl group, n is 2 or 3 and their salts, solvates and hydrates.
    Type: Application
    Filed: October 7, 2002
    Publication date: June 19, 2003
    Inventors: Peter Aranyi, Sandor Batori, Stephane Dessilla, Istvan Hermecz, Zoltan Kapui, Ferenc Levai, Endre Mikus, Marc Pascal, Lajos T. Nagy, Bruno Simonot, Katalin Urban Szabo, Marton Varga, Lelle Vasvarine Debreczy
  • Method for measuring serum cholesterol
    Patent number: 4366244
    Abstract: The invention relates to methods for measuring cholesterol of various fractions of seric lipoproteins, the methods comprising the separation of said fractions of lipoproteins by means of a lectin capable of precipitating the LDL and VLDL fractions, then measuring the amount of cholesterol in the precipitate and in the remaining solution.
    Type: Grant
    Filed: March 16, 1981
    Date of Patent: December 28, 1982
    Assignee: Laboratoires Goella
    Inventor: Marc Pascal