Abstract: The present application relates to methods of preparing Compound A: or a pharmaceutically acceptable salt or solvate thereof.

Abstract: A method for cleaning a belt of a through air drying papermaking machine in which a high pressure shower is configured to traverse across a width of the belt of the papermaking machine while ejecting water onto the belt, and a vacuum box is operatively connected to the high pressure shower. The high pressure shower has a width that is less than a full width of the belt.

Abstract: Some implementations may include a method for detecting, by a learning machine, a geobody in a seismic volume. The method may include receiving a first seismic input tile representing first seismic data from the seismic volume; receiving a first guide input tile including first labels that indicate presence of the geobody in a respective region in the seismic volume or absence of the geobody in the respective region, and one or more unlabeled regions that make no indication about presence or absence of the geobody; and determining, based on the first seismic input tile and the first guide input tile, a first prediction about geobody presence or absence in the seismic volume.

Abstract: A structured tissue belt assembly including a supporting layer, a non-woven web contacting layer, and one or more laser welds that attach the bottom surface of the web contacting layer to the top surface of the supporting layer. The structured tissue belt assembly allows for air flow in x, y and z directions. In exemplary embodiments, the structured tissue belt assembly has an embedment distance between the supporting layer and the web contacting layer of 0.05 mm to 0.60 mm and a peel force between the web contacting layer and the supporting layer of at least 650 gf/inch.

Abstract: In one embodiment, an apparatus for dispensing a liquid is disclosed. The apparatus can comprise a cap configured to connect to a container body having a chamber for containing the liquid. The cap can comprise a pour aperture through which the liquid exits the apparatus. The cap can comprise a pour lid configured to open and close the pour aperture. The cap can comprise a cap vent configured to allow air to flow from the outside environs into the chamber of the container body when the cap is connected to the container body.

Abstract: A structured tissue belt assembly including a supporting layer, a non-woven web contacting layer, and one or more laser welds that attach the bottom surface of the web contacting layer to the top surface of the supporting layer. The structured tissue belt assembly allows for air flow in x, y and z directions. In exemplary embodiments, the structured tissue belt assembly has an embedment distance between the supporting layer and the web contacting layer of 0.05 mm to 0.60 mm and a peel force between the web contacting layer and the supporting layer of at least 650 gf/inch.

Abstract: A system and method of cleaning an imprinting fabric used to make bath tissue, paper towel, or facial tissue, in which the imprinting fabric is washed with water from high pressure impact showers and flooding showers, and water remaining on the imprinting fabric after the step of washing is removed with a vacuum roll on a sheet side of the imprinting fabric. The system and method does not involve removing water from the fabric with a uhle box on the sheet side of the imprinting fabric.

Abstract: A machine or apparatus for producing structured tissue or towel using a press section.

Abstract: A structured tissue belt assembly including a supporting layer and a nonwoven web contacting layer. The supporting layer has a top surface and a bottom surface and is formed of monofilaments including one or more layers of warp yarns interwoven with weft yarns in a repeating pattern. At least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns, include laser energy absorbent material, and at least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns include laser energy scattering material. Laser welds attach the bottom surface of the web contacting layer to the top surface of the supporting layer at points where the web contacting layer contacts the at least one of: a) the at least some of the warp yarns; or b) the at least some of the weft yarns that include laser energy absorbent material.

Abstract: A through-air-dried disposable retail towel product including a laminate of at least two multi-layer plies, wherein the product has a measured Valley Volume parameter of 18 to 25 microns and a Pit Density of 16 to 25 pockets per sq. cm.

Abstract: A method of forming a fibrous web on a papermaking machine including the steps of depositing a dilute fiber slurry out of a headbox to a forming area comprising a forming surface made up of a structured fabric, wherein the structured fabric is supported by a breast roll and a forming roll, and the forming area is devoid of any additional fabrics or belts other than the structured fabric, draining the dilute fiber slurry through the structured fabric, and drying the fiber slurry.

Abstract: A method of forming a fibrous web on a papermaking machine including the steps of depositing a dilute fiber slurry out of a headbox to a forming area comprising a forming surface made up of a structured fabric, wherein the structured fabric is supported by a breast roll and a forming roll, and the forming area is devoid of any additional fabrics or belts other than the structured fabric, draining the dilute fiber slurry through the structured fabric, and drying the fiber slurry.

Abstract: A structured tissue belt assembly including a supporting layer and a nonwoven web contacting layer. The supporting layer has a top surface and a bottom surface and is formed of monofilaments including one or more layers of warp yarns interwoven with weft yarns in a repeating pattern. At least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns, include laser energy absorbent material, and at least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns include laser energy scattering material. Laser welds attach the bottom surface of the web contacting layer to the top surface of the supporting layer at points where the web contacting layer contacts the at least one of: a) the at least some of the warp yarns; or b) the at least some of the weft yarns that include laser energy absorbent material.

Abstract: The invention relates to a clothing (10) for a machine to manufacture or refine a fibrous web, in particular a paper, cardboard, or tissue web, comprising a substrate (40) and a grid structure (20) applied on the substrate (40), on which the fibrous web is transported when the clothing (10) is used as intended, wherein the grid structure (20?) comprises a plurality of first elements (24?), all of which aligned in a first direction, and a plurality of second elements (26?), all of which aligned in a second direction, which is different from the first direction, wherein the first elements (24?) penetrate the second elements (26?), forming the grid structure (20?), such that an underside of the first elements (24?) facing the substrate (40) and an underside of the second elements (26?) facing the substrate (40) are located in a common plane. In addition, the present invention relates to a method for producing such a clothing.

Abstract: Absorbent product including a laminate of at least two plies, wherein the absorbent product has a measured Valley Volume parameter greater than 11 microns and a Pit Density of greater than 25 pockets per sq·cm.

Abstract: A structured tissue belt assembly including a supporting layer, a non-woven web contacting layer, and one or more laser welds that attach the bottom surface of the web contacting layer to the top surface of the supporting layer. The structured tissue belt assembly allows for air flow in x, y and z directions. In exemplary embodiments, the structured tissue belt assembly has an embedment distance between the supporting layer and the web contacting layer of 0.05 mm to 0.60 mm and a peel force between the web contacting layer and the supporting layer of at least 650 gf/inch.

Abstract: A machine or apparatus for producing structured tissue or towel using a press section.

Abstract: A multi-channel LED driver for driving an LED fixture, wherein the multi-channel LED driver comprising a plurality of output channels, wherein each output channel is connectable to an LED or LED string of the LED fixture, the multi-channel LED driver comprising: a plurality of power converters, each power converter being associated with an output channel of the plurality of output channels, wherein each power converter comprises a switch, and wherein each power converter converts an input power at an input terminal to a current at a respective output channel of the multi-channel LED driver, a comparator configured to compare a current signal representing the current measured at an output channel by a current measurement element with a reference signal representing a current set point for the output channel, and wherein the comparator generates an output signal to control the switch of the power converter associated with the output channel, a controller arranged to determine successive, for each of the plur

Abstract: A structured tissue belt assembly including a supporting layer, a non-woven web contacting layer, and one or more laser welds that attach the bottom surface of the web contacting layer to the top surface of the supporting layer. The structured tissue belt assembly allows for air flow in x, y and z directions. In exemplary embodiments, the structured tissue belt assembly has an embedment distance between the supporting layer and the web contacting layer of 0.05 mm to 0.60 mm and a peel force between the web contacting layer and the supporting layer of at least 650 gf/inch.

Abstract: Absorbent product including a laminate of at least two plies, wherein the absorbent product has a measured Y-Connected Area parameter greater than 20 and a Surface Channel Spacing of less than 2.5 mm. The absorbent product has high strength and low machine direction stretch.