Patents by Inventor Marc Rehfuss

Marc Rehfuss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUANTITATIVE PCR SCREENING OF INDUCIBLE PROPHAGE FROM BACTERIAL ISOLATES
    Publication number: 20220356537
    Abstract: The present invention relates to methods and compositions for performing quantitative polymerase chain reaction (qPCR) to screen for previously undiscovered inducible prophages from various bacterial strains. The present invention also relates to methods for performing qPCR to identify inducible prophages for creation of functional non-replicative transcription particles (NRTPs).
    Type: Application
    Filed: December 28, 2020
    Publication date: November 10, 2022
    Inventors: Sharon Ho-Chen Chiu, Xiaowen Liu, Marc Rehfuss, Jingtao Sun, Matthew Youngblut, Rui Zhang
  • Non-replicative transduction particles and transduction particle-based reporter systems
    Patent number: 11008602
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 18, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Slav Dugenny, Ellen H Fiss, Marc Rehfuss
  • Non-replicative transduction particles and transduction particle-based reporter systems
    Patent number: 10472639
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: November 12, 2019
    Assignee: Geneweave Biosciences, Inc.
    Inventors: Diego Ariel Rey, Marc Rehfuss, Xiaowen Liu
  • NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS
    Publication number: 20190185948
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Slav Dugenny, Ellen H. Fiss, Marc Rehfuss
  • NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS
    Publication number: 20170166907
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Application
    Filed: February 16, 2017
    Publication date: June 15, 2017
    Inventors: Diego Ariel Rey, Marc Rehfuss, Xiaowen Liu