Patents by Inventor Marc Rudoltz

Marc Rudoltz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR INHIBITING TIE-2 KINASE USEFUL IN THE TREATMENT OF CANCER
    Publication number: 20190091217
    Abstract: The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
    Type: Application
    Filed: April 19, 2018
    Publication date: March 28, 2019
    Inventors: Daniel L. FLYNN, Michael D. KAUFMAN, Bryan D. SMITH, Marc RUDOLTZ
  • METHODS FOR INHIBITING TIE-2 KINASE USEFUL IN THE TREATMENT OF CANCER
    Publication number: 20170209428
    Abstract: The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
    Type: Application
    Filed: August 31, 2016
    Publication date: July 27, 2017
    Inventors: Daniel L. Flynn, Michael D. Kaufman, Brian D. Smith, Marc Rudoltz
  • Methods for inhibiting tie-2 kinase useful in the treatment of cancer
    Patent number: 9457019
    Abstract: The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravazation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: October 4, 2016
    Assignee: Deciphera Pharmaceuticals, LLC
    Inventors: Daniel L. Flynn, Michael D. Kaufman, Bryan D. Smith, Marc Rudoltz
  • METHODS FOR INHIBITING TIE-2 KINASE USEFUL IN THE TREATMENT OF CANCER
    Publication number: 20150246033
    Abstract: The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
    Type: Application
    Filed: November 7, 2014
    Publication date: September 3, 2015
    Inventors: Daniel L. Flynn, Michael D. Kaufman, Bryan D. Smith, Marc Rudoltz