Patents by Inventor Marc S. Collett

Marc S. Collett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus
    Patent number: 7217730
    Abstract: The invention is directed to methods of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of a compound of the formula: Wherein substitutions at R1, R2, R3—R12, and Y are set forth in the specification.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: May 15, 2007
    Assignees: Wyeth, ViroPharma Incorporated
    Inventors: Ariamala Gopalsamy, John W. Ellingboe, Tarek S. Mansour, Stephen M. Condon, Matthew G. Laporte, Christopher J. Burns, Kaapjoo Park, Marc S. Collett
  • Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus
    Publication number: 20040082643
    Abstract: The invention is directed to methods of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of a compound of the formula: 1
    Type: Application
    Filed: May 20, 2003
    Publication date: April 29, 2004
    Applicants: Wyeth, ViroPharma Incorporated
    Inventors: Ariamala Gopalsamy, John W. Ellingboe, Tarek S. Mansour, Stephen M. Condon, Matthew G. Laporte, Christopher J. Burns, Kaapjoo Park, Marc S. Collett
  • Methods for identifying inhibitors of helicase activity from hepatitis C virus
    Publication number: 20040076949
    Abstract: Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.
    Type: Application
    Filed: October 10, 2003
    Publication date: April 22, 2004
    Inventors: Marc S. Collett, Daniel C. Pevear, James M. Groarke, Dorothy C. Young
  • Methods for identifying inhibitors of helicase C virus
    Publication number: 20020081574
    Abstract: Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.
    Type: Application
    Filed: December 7, 2001
    Publication date: June 27, 2002
    Inventors: Marc S. Collett, Daniel C. Pevear, James M. Groarke, Dorothy C. Young
  • Vaccines against rift valley fever virus
    Patent number: 4735800
    Abstract: Methods and compositions are provided for the cloning and expression of Rift Valley Fever Virus genes in single cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce Rift Valley Fever Virus gene gene products which may be formulated for use as products which may be formulated for use as immunogens in vaccines to protect against Rift Valley Fever Virus infections.
    Type: Grant
    Filed: August 23, 1984
    Date of Patent: April 5, 1988
    Assignee: Molecular Genetics, Inc.
    Inventors: Marc S. Collett, Anthony F. Purchio
  • Molecular cloning of RNA using RNA ligase and synthetic oligonucleotides
    Patent number: 4661450
    Abstract: Methods and compositions for the insertion and molecular cloning of RNA in DNA cloning vectors are described. RNA molecules to be cloned are modified by the ligation of oligonucleotide linkers onto the termini of the RNA molecule using T4 RNA ligase. Such linkers may be composed of DNA, RNA, or mixtures of each and facilitate the insertion and ligation of the RNA species into a DNA cloning vector. The resulting recombinant vectors are used to transform host cells which provide for the generation of multiple DNA copies of the RNA molecule.
    Type: Grant
    Filed: May 3, 1983
    Date of Patent: April 28, 1987
    Assignee: Molecular Genetics Research and Development Limited Partnership
    Inventors: Tomas Kempe, Anthony F. Purchio, Marc S. Collett, William J. DeLorbe