Patents by Inventor Marc S. Gordon

Marc S. Gordon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and processes for spray drying hydrophobic and hydrophilic components
    Patent number: 8802149
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: August 12, 2014
    Assignee: Novartis Pharma AG
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • SYSTEMS AND PROCESSES FOR SPRAY DRYING HYDROPHOBIC DRUGS WITH HYDROPHILIC EXCIPIENTS
    Publication number: 20090285905
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Application
    Filed: May 20, 2009
    Publication date: November 19, 2009
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • PULMONARY DELIVERY OF POLYENE ANTIFUNGAL AGENTS
    Publication number: 20090081302
    Abstract: The present invention provides spray-dried polyene compositions for oral inhalation to the lung. The polyene antifungal compositions demonstrate superior aerosol properties, do not exhibit appreciable degradation of the polyene upon spray-drying, and are useful in the treatment and prophylaxis of both pulmonary and systemic fungal infections.
    Type: Application
    Filed: November 24, 2008
    Publication date: March 26, 2009
    Applicant: Nektar Therapeutics
    Inventors: Michael Weickert, Marc S. Gordon, Sandeep Kumar, Bing Yang, Razaq Sarwar
  • Pulmonary delivery of polyene antifungal agents
    Patent number: 7473433
    Abstract: The present invention provides spray-dried polyene compositions for oral inhalation to the lung. The polyene antifungal compositions demonstrate superior aerosol properties, do not exhibit appreciable degradation of the polyene upon spray-drying, and are useful in the treatment and prophylaxis of both pulmonary and systemic fungal infections.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: January 6, 2009
    Assignee: Nektar Therapeutics
    Inventors: Michael Weikert, Marc S. Gordon, Sandeep Kumar, Bing Yang, Razaq Sarwar
  • Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
    Publication number: 20030203036
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Application
    Filed: March 31, 2003
    Publication date: October 30, 2003
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
    Patent number: 6572893
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: June 3, 2003
    Assignee: Inhale Therapeutic Systems, Inc.
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • Inhalation lung surfactant therapy
    Publication number: 20030099601
    Abstract: Methods for providing lung surfactant therapy are provided. In particular, lung surfactant therapies effective to decrease oxygen index by inhalation of a dry powder aerosol composition are provided. The powders are preferably hollow and porous and administered via inhalation.
    Type: Application
    Filed: November 22, 2002
    Publication date: May 29, 2003
    Inventors: Marc S. Gordon, Thomas Tarara, Jeffry Weers
  • Pulmonary delivery of polyene antifungal agents
    Publication number: 20020177562
    Abstract: The present invention provides spray-dried polyene compositions for oral inhalation to the lung. The polyene antifungal compositions demonstrate superior aerosol properties, do not exhibit appreciable degradation of the polyene upon spray-drying, and are useful in the treatment and prophylaxis of both pulmonary and systemic fungal infections.
    Type: Application
    Filed: December 21, 2001
    Publication date: November 28, 2002
    Inventors: Michael Weickert, Marc S. Gordon, Sandeep Kumar, Bing Yang, Razaq Sarwar
  • Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
    Publication number: 20020132011
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Application
    Filed: February 8, 2002
    Publication date: September 19, 2002
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
    Patent number: 6365190
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 2, 2002
    Assignee: Inhale Therapeutic Systems, Inc.
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • Methods and system for processing dispersible fine powders
    Patent number: 6103270
    Abstract: The invention provides an agglomerate composition composed of units of aggregated fine particles and methods for its manufacture and use. The agglomerate composition units are composed of fine particles having a mean particle size in the range of 1 .mu.m to 5 .mu.m, and usually includes a medicament powder. The agglomerate units have a mean size in the range from 200 .mu.m to 500 .mu.m and have a friability index in the range from about 10 to 60.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: August 15, 2000
    Assignee: Inhale Therapeutic Systems
    Inventors: Keith A. Johnson, Marc S. Gordon, Shirley W. Lyons
  • Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
    Patent number: 6077543
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: June 20, 2000
    Assignee: Inhale Therapeutic Systems
    Inventors: Marc S. Gordon, Andrew Clark, Thomas K. Brewer
  • Processes for spray drying aqueous suspensions of hydrophobic drugs and compositions thereof
    Patent number: 6001336
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. The hydrophilic component is dissolved in an aqueous solution and the hydrophobic component suspended therein. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: December 14, 1999
    Assignee: Inhale Therapeutic Systems
    Inventor: Marc S. Gordon
  • Processes for spray drying solutions of hydrophobic drugs and compositions thereof
    Patent number: 5985248
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. Both the hydrophobic and hydrophilic component are dissolved in a solvent system selected to have adequate solubility for both components. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: November 16, 1999
    Assignee: Inhale Therapeutic Systems
    Inventors: Marc S. Gordon, John D. Lord
  • Processes for spray drying hydrophobic drugs in organic solvent suspensions
    Patent number: 5976574
    Abstract: Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. The hydrophobic component may be dissolved in an organic solvent and the hydrophilic component suspended therein. The method provides dry powders having relatively uniform characteristics.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: November 2, 1999
    Assignee: Inhale Therapeutic Systems
    Inventor: Marc S. Gordon
  • Methods and system for processing dispersible fine powders
    Patent number: 5922354
    Abstract: The invention provides an agglomerate composition composed of units of aggregated fine particles and methods for its manufacture and use. The agglomerate composition units are composed of fine particles having a mean particle size in the range of 1 .mu.m to 5 .mu.m, and usually includes a medicament powder. The agglomerate units have a mean size in the range from 200 .mu.m to 500 .mu.m and have a friability index in the range from about 10 to 60.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: July 13, 1999
    Assignee: Inhale Therapeutic Systems
    Inventors: Keith A. Johnson, Marc S. Gordon, Shirley W. Lyons
  • Methods and system for processing dispersible fine powders
    Patent number: 5654007
    Abstract: The invention provides an agglomerate composition composed of units of aggregated fine particles and methods for its manufacture and use. The agglomerate composition units are composed of fine particles having a mean particle size in the range of 1 .mu.m to 5 .mu.m, and usually includes a medicament powder. The agglomerate units have a mean size in the range from 200 .mu.m to 500 .mu.m and have a friability index in the range from about 10 to 60.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 5, 1997
    Assignee: Inhale Therapeutic Systems
    Inventors: Keith A. Johnson, Marc S. Gordon, Shirley W. Lyons