Patents by Inventor Marc Symons

Marc Symons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of solid tumors by inhibiting MRK/ZAK
    Patent number: 10144723
    Abstract: Methods and compounds are described for treating solid tumors, and in particular, malignant, neoplastic solid tumors such as glioblastoma and medulloblastoma, by inhibiting protein kinase MRK/ZAK activity. Also provided are pharmaceutical composition containing a MRK/ZAK inhibitor compound and a pharmaceutically acceptable carrier and a method of sensitizing tumor cells to radiation therapy comprising administering an effective amount of the MRK/ZAK inhibitor compound.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: December 4, 2018
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Rosamaria Ruggieri, Yousef Al-Abed, Marc Symons
  • TREATMENT OF SOLID TUMORS BY INHIBITING MRK/ZAK
    Publication number: 20170217929
    Abstract: Methods and compounds are described for treating solid tumors, and in particular, malignant, neoplastic solid tumors such as glioblastoma and medulloblastoma, by inhibiting protein kinase MRK/ZAK activity. Also provided are pharmaceutical composition containg a MRK/ZAK inhibitor compound and a pharmaceutically acceptable carrier and a method of sensitizing tumor cells to radiation therapy comprising administering an effective amount of the MRK/ZAK inhibitor compound.
    Type: Application
    Filed: April 21, 2015
    Publication date: August 3, 2017
    Applicant: The Feinstein Institute For Medical Research
    Inventors: Rosamaria Ruggieri, Yousef Al-Abed, Marc Symons
  • Method for treating glioblastomas and other tumors
    Patent number: 9440914
    Abstract: Methods of treating an astrocytoma with agents effective to inhibit microglia function are provided, as well as methods of enhancing the efficacy of brain tumor radiation therapy on an astrocytoma in a subject. Also provided are methods of treating other solid tumor types, and tumor cell invasion, with guanylhydrazone compounds.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 13, 2016
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Yousef Al-Abed, Marc Symons
  • METHOD FOR TREATING GLIOBLASTOMAS AND OTHER TUMORS
    Publication number: 20140323576
    Abstract: Methods of treating an astrocytoma with agents effective to inhibit microglia function are provided, as well as methods of enhancing the efficacy of brain tumor radiation therapy on an astrocytoma in a subject. Also provided are methods of treating other solid tumor types, and tumor cell invasion, with guanylhydrazone compounds.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 30, 2014
    Applicant: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Yousef Al-Abed, Marc Symons, Anthony J. Hesketh, Samuel Z. Soffer