Patents by Inventor Marc Therrien

Marc Therrien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200079443
    Abstract: A vehicle includes a plurality of track systems, a fluid pump, a plurality of fluid lines fluidly connecting the fluid pump to at least some of the tires of the wheels of each of the track systems, a plurality of pneumatic inflation actuators, a plurality of pneumatic deflation actuators, and a system controller. The system controller is in electronic communication with the fluid pump, the plurality of pneumatic inflation actuators, and the plurality of pneumatic deflation actuators. The system controller is operable to selectively adjust fluid pressure in select ones of the wheels of any one of the track systems of the vehicle by actuating corresponding ones of the plurality of pneumatic inflation actuators and the plurality of pneumatic deflation actuators. A track system has at least one of the leading idler wheels, trailing idler wheels, and mid-roller wheels including a tire containing a fluid.
    Type: Application
    Filed: September 6, 2019
    Publication date: March 12, 2020
    Inventors: Yves SAUVAGEAU, Pierre-Yves PEPIN, Marc NADEAU, Branislav NANAC, Genevieve THERRIEN, Andre TODD, Ariane LEPAGE-HURTEAU, Cedric ALLIGUIE, Jonathan LAPALME, Nicolas DUBUC, Philippe JAILLET-GOSSELIN
  • Patent number: 10558223
    Abstract: There is provided an autonomous vehicle for pushing feed lying on a floor, comprising a frame; a skirt rotatably connected to the frame, wherein a bottom portion of the skirt continuously contacts the floor to push the feed. The vehicle comprises a sensor assembly for detecting a magnetic field emitted from a magnetic guiding element inserted in the floor and a control unit mounted for directing rotation of the skirt and for guiding the vehicle along a predetermined path formed by the magnetic guiding element. Also provided is an autonomous vehicle with a skirt drive mechanism mounted to the frame for driving rotation of the skirt, and an autonomous vehicle comprising a prism-shaped skirt rotatably connected to the frame. There is also provided methods for installing a magnetically guided autonomous vehicle and for pushing feed using an autonomous vehicle, as well as systems and kits comprising said vehicle.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: February 11, 2020
    Assignee: ROVIBEC INC.
    Inventors: Francis Leclair, Pascal Leclerc, Marc-Antoine Durand, Richard Fleurent, Marjolaine Marcotte, Yvon Therrien, Jean-Pierre Malleret, Kevin Rousseau, Victor Rousseau, Martin Rousseau, Claude Beauregard
  • Patent number: 9464313
    Abstract: Disclosed herein are biosensors useful for detecting the dimerization of RAF and/or KSR polypeptides. These biosensors comprise fusion proteins comprising RAF and/or KSR proteins fused to bioluminescent or fluorescent proteins. Also disclosed are methods of using the biosensors to detect and measure the dimerization of RAF/RAF and RAF/KSR polypeptides by resonance energy transfer such as BRET or FRET, for example to screen for inhibitors of dimerization.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: October 11, 2016
    Assignees: MOUNT SINAI HOSPITAL, UNIVERSITÉ DE MONTRÉAL
    Inventors: Hugo Lavoie, Malha Sahmi, Marc Therrien, Thanashan Rajakulendran, Frank Sicheri
  • Publication number: 20140378324
    Abstract: Disclosed herein are mutated RAF and KSR nucleic acids and polypeptides. Also disclosed are methods of using the mutated RAF and KSR to inhibit the dimerization of RAF/RAF and RAF/KSR. Also disclosed are methods of using the mutated RAF and KSR to screen for inhibitors of dimerization.
    Type: Application
    Filed: December 20, 2013
    Publication date: December 25, 2014
    Applicants: MOUNT SINAI HOSPITAL, UNIVERSITE DE MONTREAL
    Inventors: HUGO LAVOIE, Malha Sahmi, Marc Therrien, Thanashan Rajakulendran, Frank Sicheri
  • Publication number: 20120190039
    Abstract: Disclosed herein are mutated RAF and KSR nucleic acids and polypeptides. Also disclosed are methods of using the mutated RAF and KSR to inhibit the dimerization of RAF/RAF and RAF/KSR. Also disclosed are methods of using the mutated RAF and KSR to screen for inhibitors of dimerization.
    Type: Application
    Filed: January 23, 2012
    Publication date: July 26, 2012
    Inventors: Hugo Lavoie, Malha Sahmi, Marc Therrien, Thanashan Rajakulendran, Frank Sicheri
  • Publication number: 20090042233
    Abstract: A polypeptide comprising a SAM domain, the sequence of said SAM domain being as set forth in SEQ ID NO: 33.
    Type: Application
    Filed: April 2, 2007
    Publication date: February 12, 2009
    Inventors: Marc THERRIEN, Malha Sahmi, Melanie Douziech
  • Patent number: 5747275
    Abstract: The kinase suppressor of Ras (Ksr), a novel protein kinase involved in the regulation of cell growth and differentiation, provides an important target for therapeutic intervention. The subject compositions also include nucleic acids which encode a Ksr kinase, and hybridization probes and primers capable of hybridizing with a Ksr gene. Such probes are used to identify mutant Ksr alleles associated with disease. The invention includes methods, including phosphorylation and binding assays, for screening chemical libraries for lead compounds for a pharmacological agent useful in the diagnosis or treatment of disease associated Ksr activity or Ksr-dependent signal transduction.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: May 5, 1998
    Assignee: The Regents of the University of California
    Inventors: Gerry Rubin, Marc Therrien, Henry Chang, Felix Karim, David Wassarman
  • Patent number: 5747288
    Abstract: The kinase suppressor of Ras (Ksr), a novel protein kinase involved in the regulation of cell growth and differentiation, provides an important target for therapeutic intervention. The subject compositions also include nucleic acids which encode a Ksr kinase, and hybridization probes and primers capable of hybridizing with a Ksr gene. Such probes are used to identify mutant Ksr alleles associated with disease. The invention includes methods, including phosphorylation and binding assays, for screening chemical libraries for lead compounds for a pharmacological agent useful in the diagnosis or treatment of disease associated Ksr activity or Ksr-dependent signal transduction.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: May 5, 1998
    Assignee: The Regents of the University of California
    Inventors: Gerry Rubin, Marc Therrien, Henry Chang, Felix Karim, David Wassarman
  • Patent number: 5700675
    Abstract: The kinase suppressor of Ras (Ksr), a novel protein kinase involved in the regulation of cell growth and differentiation, provides an important target for therapeutic intervention. The subject compositions also include nucleic acids which encode a Ksr kinase, and hybridization probes and primers capable of hybridizing with a Ksr gene. Such probes are used to identify mutant Ksr alleles associated with disease. The invention includes methods, including phosphorylation and binding assays, for screening chemical libraries for lead compounds for a pharmacological agent useful in the diagnosis or treatment of disease associated Ksr activity or Ksr-dependent signal transduction.
    Type: Grant
    Filed: December 13, 1995
    Date of Patent: December 23, 1997
    Assignee: Regents of the University of California
    Inventors: Gerry Rubin, Marc Therrien, Henry Chang, Felix Karim, David Wassarman