Abstract: Methods and devices for detection of micro-organisms present or suspected to be present within a mammalian blood sample are provided. A selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

Abstract: Methods and devices for detection of micro-organisms present or suspected to be present within a mammalian blood sample are provided. A selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

Abstract: Methods and devices for the selective lysis of cells in a sample comprising micro-organisms such as bacteria are provided. The selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

Abstract: A light emitting device comprises a substrate (61) and an arrangement of light emitting elements (62) provided over the substrate. The substrate has a contoured surface which defines at least first and second regions (60a, 60b, 60c), having normal directions which face in different directions. The light emitting elements (62) comprise directional light emitting elements, and are provided on the first and second regions (60b, 60c), thereby to define first and second light emission directions. This arrangement provides light source elements on a structured (topographically non-flat) substrate in a device, such that the angular distribution of light emitted by the device can be electronically adapted by controlling the light emission per light-emitting area.

Abstract: The invention relates to a microelectronic sensor device and a method for the investigation of biological target substances (20), for example oligonucleotides like DNA fragments. In one embodiment, the device comprises a reaction surface (RS) to which target specific reactants (10) are attached and which lies between a sample chamber (SC) and an array of selectively controllable heating elements (HE). The temperature profile in the sample chamber (SC) can be controlled as desired to provide for example conditions for a PCR and/or for a controlled melting of hybridizations. The reactant (10) and/or the target substance (20) comprises a label (12) with an observable property, like fluorescence, that changes if the target substance (20) is bound to the reactant (10), said property being detected by an array of sensor elements, for example photosensors (SE).

Abstract: The invention relates to different designs of a microelectronic device comprising an array of heating elements (HE) with local driving units (CU2) and optionally with an array of sensor elements (SE) adjacent to a sample chamber (SC). By applying appropriate currents to the heating elements (HE), the sample chamber can be heated according to a desired temperature profile. The local driving units comprise means for compensating variations of their individual characteristics.

Abstract: Methods and devices for the selective lysis of cells in a sample comprising micro-organisms such as bacteria are provided. The selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

Abstract: The invention relates to different designs of a microelectronic sensor device comprising an array of heating elements (HE) and an array of sensor elements (SE) that are aligned with respect to each other adjacent to a sample chamber (SC). By applying appropriate currents to the heating elements (HE), the sample chamber can be heated according to a desired temperature profile.

Abstract: A multi view display comprising a light emitting element having an optical cavity formed by a first and a second reflecting layer, at least said second reflecting layer being semi-transparent, and a light emitting layer arranged between said reflecting layers, wherein said optical cavity is designed so that light emitted in at least two preferred viewing directions has a higher intensity than light emitted in other directions. The invention is based on interference phenomena in the optical cavity, making it possible to realize a light emitting element that intrinsically emits more light in the preferential viewing directions than in other directions. This emission profile makes the light emitting element very useful in a multi view display, reducing the problems of cross talk.

Abstract: The present invention relates to a magnetic field generation device comprising a magnetic field generating element (101) and a limiter (103) for limiting a magnitude of a current through the magnetic field generating element (101).

Abstract: A display panel includes pixels with a light emissive layer and an electrode layer deposited on the light emissive layer. A first pixel is determined by a first barrier structure and a second pixel, adjacent to the first pixel, is determined by a second barrier structure. The first and second barrier structures are separated by an electrically conductive structure in electrical contact with the electrode layer. Accordingly, space is available between the barrier structures for electrical shunting of the electrode layer.

Abstract: The present invention provides a microfluidic device. The microfluidic device comprises a first fluidic compartment (10) and a second fluidic compartment (11). The microfluidic device furthermore comprises at least one micromechanical actuator element (14) for, when in use, forcing a sample fluid to flow from the first fluidic compartment (10) into the second fluidic compartment (11).

Abstract: A sensor cartridge has a cartridge substrate comprising an optical substrate for optical detection of a target moiety in a sample fluid based on frustrated totalinternal reflection and at least one electric structure. This way, optical read-out and electrical functions, e.g. read-out, are combined in a single substrate, in a simple and cheap manner. Also a method of fabricating such sensor cartridge is provided.

Abstract: The invention relates to different designs of a microelectronic sensor device comprising an array of heating elements (HE) and an array of sensor elements (SE) that are aligned with respect to each other adjacent to a sample chamber (SC). By applying appropriate currents to the heating elements (HE), the sample chamber can be heated according to a desired temperature profile.

Abstract: The present invention relates to a magnetic field generation device comprising a magnetic field generating element (101) and a limiter (103) for limiting a magnitude of a current through the magnetic field generating element (101).

Abstract: The invention relates to a microelectronic device, particularly a microelectronic biosensor, comprising an array of field electrodes (FE) for generating an alternating electrical field (E) in an adjacent sample chamber (SC). The field electrodes (FE) are coupled to associated local oscillators (OS), which are preferably tunable and connected in a matrix pattern to an external control unit (CU). The local oscillators (OS) allow high frequencies of the generated electrical fields (E), such that for example dielectrophoretic forces can be generated.

Abstract: The invention relates to different designs of a microelectronic device comprising an array of heating elements (HE) with local driving units (CU2) and optionally with an array of sensor elements (SE) adjacent to a sample chamber (SC). By applying appropriate currents to the heating elements (HE), the sample chamber can be heated according to a desired temperature profile. The local driving units comprise means for compensating variations of their individual characteristics.

Abstract: The invention relates to different designs of a microelectronic device comprising heating electrodes (HE) and field electrodes (FE) that have effect in the same sub-region of a sample chamber. By applying appropriate voltages to the field electrodes (FE), an electrical field (E) can be generated in the sample chamber. By applying appropriate currents to the heating electrodes (HE), the sample chamber can be heated according to a desired temperature profile. The heating electrodes (HE) may optionally be operated as field electrodes such that they generate an electrical field in the sample chamber, too.

Abstract: A radiation detection system (100) is described comprising a measurement region (104) in a measurement chamber adapted for receiving at least one sample (108) to be examined and adapted for receiving excitation radiation for impingement on the at least one sample (108) and for generating sample radiation. The radiation detection system (100) furthermore comprises at least one detector element (106) for detection of the generated sample radiation. The radiation detection system thereby is a front irradiation system, i.e. the excitation radiation is incident on a first side of the measurement region (104) in a measurement chamber and the at least one detector element (106) is positioned at a second side of the measurement region (104) in a measurement chamber, the second side being opposite to the first side with respect to the measurement region (104) in a measurement chamber, such that detection occurs at the side facing the first side.

Abstract: The present invention provides a luminescence sensor (20) comprising at least one chamber (22) and at least one optical filter formed by at least a first conductive grating (11), the at least first conductive grating (11) comprising a plurality of wires (12), wherein at least one of the wires (12) of the at least first conductive grating (11) is linked to a temperature control device for controlling the temperature of at least one chamber (22) in the sensor.