Patents by Inventor Marc Zabeau

Marc Zabeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120214706
    Abstract: The present invention relates to the rapid detection of clusters of single nucleotide polymorphisms (SNPs) using an array technology. It further relates to the use of these clusters as markers in strain improvement and breeding, and in strain identification.
    Type: Application
    Filed: October 5, 2010
    Publication date: August 23, 2012
    Inventor: Marc Zabeau
  • Patent number: 7996157
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: August 9, 2011
    Assignee: Methexis Genomics N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Patent number: 7974789
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: July 5, 2011
    Assignee: Methexis Genomics N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Publication number: 20110104677
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. This technology can be applied to human, animal or plant DNA fingerprinting, to identify restriction fragment length polymorphisms. Also encompassed by the inventive technology are kits for the application of the process.
    Type: Application
    Filed: July 18, 2010
    Publication date: May 5, 2011
    Inventors: MARC ZABEAU, PIETER VOS
  • Patent number: 7935488
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. This technology can be applied to human, animal or plant DNA fingerprinting, to identify restriction fragment length polymorphisms. Also encompassed by the inventive technology are kits for the application of the process.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: May 3, 2011
    Assignee: Keygene N.V.
    Inventors: Marc Zabeau, Pieter Vos
  • Publication number: 20110059457
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. This technology can be applied to human, animal or plant DNA fingerprinting, to identify restriction fragment length polymorphisms. Also encompassed by the inventive technology are kits for the application of the process.
    Type: Application
    Filed: October 5, 2010
    Publication date: March 10, 2011
    Inventors: MARC ZABEAU, PIETER VOS
  • Publication number: 20100323353
    Abstract: The present invention is directed at a novel method to enhance the genetic improvement of industrial microorganisms. More specifically, the present invention is directed at molecular methods for the identification of genetic variants that contribute to the genetic improvement of the microorganisms. The methods of the present invention comprise novel approaches for identifying genetic markers that linked to said genetic variants, and for using said genetic markers to select improved industrial microorganisms. In one of the embodiments, the genetic markers linked to said genetic variants are identified in microbial populations that are subjected to directed evolution. In another embodiment the genetic markers linked to said genetic variants are identified in microbial sub populations that have been prescreened for improved characteristics.
    Type: Application
    Filed: November 27, 2008
    Publication date: December 23, 2010
    Inventor: Marc Zabeau
  • Publication number: 20100267023
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. Application of this process to human, animal or plant DNA fingerprinting, to identification of restriction fragment length polymorphisms. Kit for the application of the process.
    Type: Application
    Filed: June 15, 2009
    Publication date: October 21, 2010
    Inventors: Marc Zabeau, Pieter Vos
  • Publication number: 20100092964
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Application
    Filed: July 29, 2009
    Publication date: April 15, 2010
    Applicant: METHEXIS GENOMICS N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Publication number: 20100082261
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Application
    Filed: September 3, 2009
    Publication date: April 1, 2010
    Applicant: METHEXIS GENOMICS N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Patent number: 7593818
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: September 22, 2009
    Assignee: Methexis Genomics N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Patent number: 7584058
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Grant
    Filed: February 26, 2004
    Date of Patent: September 1, 2009
    Assignee: Methexis Genomics N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Patent number: 7572583
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. Application of this process to human, animal or plant DNA fingerprinting, to identification of restriction fragment length polymorphisms. Kit for the application of the process.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: August 11, 2009
    Assignee: Keygene N.V.
    Inventors: Marc Zabeau, Pieter Vos
  • Publication number: 20090104601
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Application
    Filed: March 9, 2006
    Publication date: April 23, 2009
    Applicant: Methexis Genomics N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Publication number: 20060257888
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Application
    Filed: December 19, 2005
    Publication date: November 16, 2006
    Applicant: METHEXIS GENOMICS, N.V.
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans
  • Publication number: 20060252061
    Abstract: The present invention is in the field of nucleic acid-based diagnostic assays. More particularly, it relates to methods useful for the “diagnostic sequencing” of regions of sample nucleic acids for which a prototypic or reference sequence is already available (also referred to as “re-sequencing”), or which may be determined using the methods described herein. This diagnostic technology is useful in areas that require such re-sequencing in a rapid and reliable way: (i) the identification of the various allelic sequences of a certain region/gene, (ii) the scoring of disease-associated mutations. (iii) the detection of somatic variations, (iv) studies in the field of molecular evolution, (v) the determination of the nucleic acid sequences of prokaryotic and eukaryotic genomes; (vi) identifying one or more nucleic acids in one or more biological samples; (vii) and determining the expression profile of genes in a biological sample and other areas.
    Type: Application
    Filed: February 6, 2006
    Publication date: November 9, 2006
    Applicant: Sequenom, Inc.
    Inventors: Marc Zabeau, Patrick Stanssens
  • Patent number: 7026115
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part or its nucleic acid is unknown. Application of this process to human, animal or plant DNA fingerprinting, to identification of restriction fragment length polymorphisms. Kit for the application of the process.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: April 11, 2006
    Assignee: Keygene N.V.
    Inventors: Marc Zabeau, Pieter Vos
  • Publication number: 20060035261
    Abstract: The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. Application of this process to human, animal or plant DNA fingerprinting, to identification of restriction fragment length polymorphisms. Kit for the application of the process.
    Type: Application
    Filed: August 17, 2005
    Publication date: February 16, 2006
    Applicant: Keygene N.V.
    Inventors: Marc Zabeau, Pieter Vos
  • Patent number: 6994969
    Abstract: The present invention is in the field of nucleic acid-based diagnostic assays. More particularly, it relates to methods useful for the “diagnostic sequencing” of regions of sample nucleic acids for which a prototypic or reference sequence is already available (also referred to as “re-sequencing”), or which may be determined using the methods described herein. This diagnostic technology is useful in areas that require such re-sequencing in a rapid and reliable way: (i) the identification of the various allelic sequences of a certain region/gene, (ii) the scoring of disease-associated mutations, (iii) the detection of somatic variations, (iv) studies in the field of molecular evolution, (v) the determination of the nucleic acid sequences of prokaryotic and eukaryotic genomes, (vi) identifying one or more nucleic acids in one or more biological samples', (vii) and determining the expression profile of genes in a biological sample and other areas.
    Type: Grant
    Filed: April 30, 2000
    Date of Patent: February 7, 2006
    Assignee: Methexis Genomics, N.V.
    Inventors: Marc Zabeau, Patrick Stanssens
  • Publication number: 20050277135
    Abstract: The present invention is in the field of nucleic acid-based genetic analysis. More particularly, it discloses novel insights into the overall structure of genetic variation in all living species. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The invention is useful to define the subset of variations that are most suited as genetic markers to search for correlations with certain phenotypic traits. Additionally, the insights are useful for the development of algorithms and computer programs that convert genotype data into the constituent haplotypes that are laborious and costly to derive in an experimental way. The invention is useful in areas such as (i) genome-wide association studies, (ii) clinical in vitro diagnosis, (iii) plant and animal breeding, (iv) the identification of micro-organisms.
    Type: Application
    Filed: March 9, 2005
    Publication date: December 15, 2005
    Applicant: METHEXIS GENOMICS NV
    Inventors: Marc Zabeau, Patrick Stanssens, Yannick Gansemans