Patents by Inventor Marc Zelsmann
Marc Zelsmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12275980Abstract: Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.Type: GrantFiled: November 13, 2020Date of Patent: April 15, 2025Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPESInventors: Prisca Perlemoine, Thomas Bordy, Pierre Marcoux, Emmanuel Picard, Rémi Toutain, Marc Zelsmann, Alexis Maire
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Publication number: 20240309422Abstract: A method for detecting a lytic activity of one or more types of phages or of the activity of one or more antibiotics with respect to a bacterial strain, the method including using a first multiwell plate, each well receiving a sample containing phages or antibiotics, making at least one deposit on a transparent area of a support, the deposit containing bacteria of the bacterial strain, applying the first plate against the support so that each sample in each well comes into contact with the deposit, for each well, determining, using the detection means, the activity or absence of activity of the phage or antibiotic with respect to the bacterial strain, taking into account the intensity of light signals transmitted through each well and/or the variation thereof over time.Type: ApplicationFiled: March 14, 2024Publication date: September 19, 2024Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Pierre MARCOUX, Yoann ROUPIOZ, Marc ZELSMANN, Emmanuel PICARD, Larry O’CONNELL
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Patent number: 12019397Abstract: A method for obtaining an image of a sample includes illuminating the sample using a light source; acquiring, using an image sensor, a first image of the sample, the image being formed in the detection plane, the first image being representative of an exposure light wave propagating, from the sample, to the image sensor, along a first optical path; modifying an optical refractive index, between the image sensor and the sample; acquiring a second image of the sample, the image being representative of the exposure light wave along a second optical path; and implementing an iterative algorithm that combines the first and second images so as to obtain an image of the sample.Type: GrantFiled: December 28, 2021Date of Patent: June 25, 2024Assignees: Commissariat à l'Energie Atomique et aux Energies Alternatives, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ GRENOBLE ALPESInventors: Marc Zelsmann, Pierre Marcoux, Emmanuel Picard
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Publication number: 20240111217Abstract: The invention relates to a method of directional self-assembly lithography, said method comprising a step of depositing a block copolymer film on a layer (20) neutral with respect the block copolymer, said block copolymer film being for use as a lithography mask, said method being characterized in that it comprises the following steps of: depositing said neutral layer (20) on a surface of a substrate (10), said neutral layer (20) being of the carbon or fluoro-carbon type deposited to a thickness greater than 1.Type: ApplicationFiled: October 15, 2020Publication date: April 4, 2024Inventors: Xavier Chevalier, Matthieu Sérégé, Cindy Gomes Correia, Marc Zelsmann, Guillaume Fleury
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Publication number: 20230012890Abstract: The invention relates to a method for nanostructuring a substrate (10) for the preparation of a nanostructured substrate having nanostructures of different dimensions, the method including removing the crosslinked polymer layer (TC) and one of the blocks of the nanostructured block copolymer so as to form patterns of a nanolithography mask; said method being characterized in that the removal of one of the blocks is a removal of only a portion of the nanodomains (21, 22) of one of the blocks of the nanostructured block copolymer, in particular of only the perpendicular nanodomains (Z1) of said block, such that the parallel nanodomains (21, 22) of at least two blocks of the nanostructured block copolymer form patterns of the nanolithography mask; and so as to generate in the nanolithography mask patterns (M1, M2, M3) of different dimensions and nanostructures in the nanostructured substrate of different dimensions after etching.Type: ApplicationFiled: December 29, 2020Publication date: January 19, 2023Inventors: Xavier Chevalier, Marc Zelsmann, Christophe Navarro, Gwenaëlle Pound-Lana
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Publication number: 20220214648Abstract: Method for obtaining an image of a sample (10), comprising: a) illuminating the sample using a light source (11); b) acquiring, using an image sensor (16), a first image (I1,P0) of the sample (10), said image being formed in the detection plane (P0), the first image being representative of an exposure light wave (14) propagating, from the sample, to the image sensor, along a first optical path (L1); the method comprising, following b) c) modifying an optical refractive index, between the image sensor and the sample; d) following c), acquiring a second image (I2,P0) of the sample, said image being representative of the exposure light wave (14) along a second optical path (L2); e) implementing an iterative algorithm that combines the first and second images so as to obtain an image of the sample.Type: ApplicationFiled: December 28, 2021Publication date: July 7, 2022Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ GRENOBLE ALPESInventors: Marc ZELSMANN, Pierre MARCOUX, Emmanuel PICARD
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Publication number: 20210147899Abstract: Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.Type: ApplicationFiled: November 13, 2020Publication date: May 20, 2021Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPESInventors: Prisca PERLEMOINE, Thomas BORDY, Pierre MARCOUX, Emmanuel PICARD, Rémi TOUTAIN, Marc ZELSMANN, Alexis MAIRE
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Patent number: 9839938Abstract: Device (10) for depositing particles via the liquid route including a first chamber a second chamber (12), a communication hole between the first chamber (11) and the second chamber (12), and a vent which is provided in the second chamber and which places the second chamber and a medium (200) which is external with respect to the device in communication.Type: GrantFiled: May 7, 2015Date of Patent: December 12, 2017Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CNRS, UNIVERSITE JOSEPH FOURIER-GRENABLEInventors: Emmanuel Picard, Julien Cordeiro, Kévin Berton, David Peyrade, Marc Zelsmann
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Publication number: 20150321216Abstract: Device (10) for depositing particles via the liquid route including a first chamber (11), a second chamber (12), a communication hole between the first chamber (11) and the second chamber (12), and a vent which is provided in the second chamber and which places the second chamber and a medium (200) which is external with respect to the device in communication.Type: ApplicationFiled: May 7, 2015Publication date: November 12, 2015Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, CNRS, UNIVERSITE JOSEPH FOURIER - GRENOBLEInventors: Emmanuel Picard, Julien Cordeiro, Kévin Berton, David Peyrade, Marc Zelsmann