Patents by Inventor Marcel DEKEN

Marcel DEKEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AUTOTAXIN (ATX) INHIBITOR FOR THE TREATMENT OF PANCREATIC CANCER
    Publication number: 20250057820
    Abstract: An autotaxin (ATX) inhibitor or a pharmaceutically acceptable salt thereof for use in a method of treatment of pancreatic cancer in a patient, optionally wherein the method further comprises administration of a TGF-? pathway inhibitor and/or an additional chemotherapeutic agent.
    Type: Application
    Filed: June 8, 2022
    Publication date: February 20, 2025
    Inventors: Zoë JOHNSON, Marcel DEKEN, Michael LAHN, Davide MELISI
  • ANTI-CD73 ANTIBODIES
    Publication number: 20240117065
    Abstract: This invention relates to anti-CD73 antibody molecules that include a VH domain comprising a VHCDR1 of SEQ ID NO: 1, a VHCDR2 of SEQ ID NO: 2, and a VHCDR3 of SEQ ID NO: 3; and a VL domain comprising a VLCDR1 of SEQ ID NO: 4, a VLCDR2 of SEQ ID NO: 5, and a VLHCDR3 of SEQ ID NO: 6. Antibody molecules and methods for their production and use in therapy, for example for treating cancer or reducing tumor-mediated immunosuppression are provided.
    Type: Application
    Filed: April 8, 2022
    Publication date: April 11, 2024
    Inventors: Lorna STEWART, Grainne GERNON, Zoë JOHNSON, Marcel DEKEN