Patents by Inventor Marcel Hoekman

Marcel Hoekman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10180390
    Abstract: A flow cytometry system having a flow channel defined through the thickness of a substrate is disclosed. Fluid flowing through the flow channel is illuminated by a first plurality of surface waveguides that are arranged around the flow channel in a first plane, while a second plurality of surface waveguides arranged around the flow channel in a second plane receive light after it has interacted with the fluid. The illumination pattern provided to the fluid is controlled by controlling the phase of the light in the first plurality of surface waveguides. As a result, the fluid is illuminated with light that is uniform and has a low coefficient of variation, improving the ability to distinguish and quantify characteristics of the fluid, such as cell count, DNA content, and the like.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: January 15, 2019
    Assignee: LioniX International BV
    Inventors: Frederik Schreuder, Marcel Hoekman, Ronald Dekker, Seyed Naser Hosseini
  • Patent number: 9939582
    Abstract: A method for forming a non-linear thickness-profile in a first layer of a first material is disclosed. The method comprises forming an accelerator layer of a second material on the first layer and forming a mask layer disposed on the accelerator layer, wherein the mask layer enables the accelerator layer to expose the first layer to a first etchant in a first region, where the exposure time for each point along a first axis varies non-linearly as a function of distance from a first point on the first axis. Since the time for which the first layer is exposed to the first etch in the first region is non-linear, the thickness of the first layer in the first region changes non-linearly along the first axis.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: April 10, 2018
    Assignee: LioniX International BV
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Patent number: 9453791
    Abstract: A flow cytometry system having a flow channel defined through the thickness of a substrate is disclosed. Fluid flowing through the flow channel is illuminated by a first plurality of surface waveguides that are arranged around the flow channel in a first plane, while a second plurality of surface waveguides arranged around the flow channel in a second plane receive light after it has interacted with the fluid. The illumination pattern provided to the fluid is controlled by controlling the phase of the light in the first plurality of surface waveguides. As a result, the fluid is illuminated with light that is uniform and has a low coefficient of variation, improving the ability to distinguish and quantify characteristics of the fluid, such as cell count, DNA content, and the like.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: September 27, 2016
    Assignee: OctroliX BV
    Inventors: Frederik Schreuder, Marcel Hoekman, Ronald Dekker, Seyed Naser Hosseini
  • Publication number: 20160266029
    Abstract: A flow cytometry system having a flow channel defined through the thickness of a substrate is disclosed. Fluid flowing through the flow channel is illuminated by a first plurality of surface waveguides that are arranged around the flow channel in a first plane, while a second plurality of surface waveguides arranged around the flow channel in a second plane receive light after it has interacted with the fluid. The illumination pattern provided to the fluid is controlled by controlling the phase of the light in the first plurality of surface waveguides. As a result, the fluid is illuminated with light that is uniform and has a low coefficient of variation, improving the ability to distinguish and quantify characteristics of the fluid, such as cell count, DNA content, and the like.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 15, 2016
    Inventors: Frederik Schreuder, Marcel Hoekman, Ronald Dekker, Seyed Naser Hosseini
  • Publication number: 20160246003
    Abstract: A method for forming a non-linear thickness-profile in a first layer of a first material is disclosed. The method comprises forming an accelerator layer of a second material on the first layer and forming a mask layer disposed on the accelerator layer, wherein the mask layer enables the accelerator layer to expose the first layer to a first etchant in a first region, where the exposure time for each point along a first axis varies non-linearly as a function of distance from a first point on the first axis. Since the time for which the first layer is exposed to the first etch in the first region is non-linear, the thickness of the first layer in the first region changes non-linearly along the first axis.
    Type: Application
    Filed: January 22, 2016
    Publication date: August 25, 2016
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Patent number: 9268089
    Abstract: A method for forming a non-linear thickness-profile in a first layer of a first material is disclosed. The method comprises forming an accelerator layer of a second material on the first layer and forming a mask layer disposed on the accelerator layer, wherein the mask layer enables the accelerator layer to expose the first layer to a first etchant in a first region, where the exposure time for each point along a first axis varies non-linearly as a function of distance from a first point on the first axis. Since the time for which the first layer is exposed to the first etch in the first region is non-linear, the thickness of the first layer in the first region changes non-linearly along the first axis.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: February 23, 2016
    Assignee: Octrolix BV
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Publication number: 20160003730
    Abstract: A flow cytometry system having a flow channel defined through the thickness of a substrate is disclosed. Fluid flowing through the flow channel is illuminated by a first plurality of surface waveguides that are arranged around the flow channel in a first plane, while a second plurality of surface waveguides arranged around the flow channel in a second plane receive light after it has interacted with the fluid. The illumination pattern provided to the fluid is controlled by controlling the phase of the light in the first plurality of surface waveguides. As a result, the fluid is illuminated with light that is uniform and has a low coefficient of variation, improving the ability to distinguish and quantify characteristics of the fluid, such as cell count, DNA content, and the like.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 7, 2016
    Inventors: Frederik Schreuder, Marcel Hoekman, Ronald Dekker, Seyed Naser Hosseini
  • Publication number: 20140286616
    Abstract: A method for forming a non-linear thickness-profile in a first layer of a first material is disclosed. The method comprises forming an accelerator layer of a second material on the first layer and forming a mask layer disposed on the accelerator layer, wherein the mask layer enables the accelerator layer to expose the first layer to a first etchant in a first region, where the exposure time for each point along a first axis varies non-linearly as a function of distance from a first point on the first axis. Since the time for which the first layer is exposed to the first etch in the first region is non-linear, the thickness of the first layer in the first region changes non-linearly along the first axis.
    Type: Application
    Filed: May 5, 2014
    Publication date: September 25, 2014
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Patent number: 8718432
    Abstract: A method for forming a tapered region in a first layer of a first material is disclosed. The method comprises forming an accelerator layer of a second material on the first layer and forming a mask layer disposed on the accelerator layer. The accelerator layer is exposed to a first etch that removes the second material in a first region and laterally etches the accelerator layer along a second region to expose the first layer in the second region to the first etch. Since the time for which the first layer is exposed to the first etch in the second region is based on the progress of the lateral etch of the accelerator layer, the first etch tapers the first layer in the second region.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: May 6, 2014
    Assignee: Octrolix BV
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Patent number: 8494323
    Abstract: A system having an optical-coupling region for evanescently coupling light between first and second optical-waveguiding structures is disclosed. Within the optical-coupling region, the first and second optical-waveguiding structures exhibit mirror symmetry with respect to each other across or about at least one of a plane and an axis and include a segment that is not straight.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: July 23, 2013
    Assignee: Octrolix BV
    Inventors: Marcel Hoekman, Rene Gerrit Heideman, Albert Prak
  • Publication number: 20120134628
    Abstract: A system having an optical-coupling region for evanescently coupling light between first and second optical-waveguiding structures is disclosed. Within the optical-coupling region, the first and second optical-waveguiding structures exhibit mirror symmetry with respect to each other across or about at least one of a plane and an axis and include a segment that is not straight.
    Type: Application
    Filed: November 29, 2010
    Publication date: May 31, 2012
    Applicant: OCTROLIX BV
    Inventors: Marcel Hoekman, Rene Gerrit Heideman, Albert Prak
  • Patent number: 7146087
    Abstract: The illustrative embodiment of the invention is a surface waveguide having low modal birefringence. The surface waveguide has a composite guiding region that is sandwiched by a lower cladding layer and an upper cladding layer, wherein the cladding layers serve to confine propagating light to the composite guiding region. In accordance with the illustrative embodiment, the composite guiding region is structured so that it exhibits a balanced stress configuration, wherein the stress in the direction that aligns with the TE polarization mode is substantially equal to the stress in the direction that aligns with the TM polarization mode. The balanced stress configuration results in a surface waveguide that exhibits very low modal birefringence.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: December 5, 2006
    Assignee: LioniX BV
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Patent number: 7142759
    Abstract: A surface waveguide is disclosed. In the illustrative embodiment, the waveguide has a core and an upper and lower cladding. The core has a thickness that is greater than the critical thickness of the material that composes the core. This is achieved by depositing/growing the core as a conformal layer within a region that is recessed from the planar surface of the lower cladding, wherein the recessed region has a width that is no more than twice the critical thickness of the core material.
    Type: Grant
    Filed: January 12, 2005
    Date of Patent: November 28, 2006
    Assignee: Lionix BV
    Inventors: Rene Gerrit Heideman, Marcel Hoekman
  • Publication number: 20050180713
    Abstract: A surface waveguide is disclosed. In the illustrative embodiment, the waveguide has a core and an upper and lower cladding. The core has a thickness that is greater than the critical thickness of the material that composes the core. This is achieved by depositing/growing the core as a conformal layer within a region that is recessed from the planar surface of the lower cladding, wherein the recessed region has a width that is no more than twice the critical thickness of the core material.
    Type: Application
    Filed: January 12, 2005
    Publication date: August 18, 2005
    Applicant: LioniX BV
    Inventors: Rene Heideman, Marcel Hoekman
  • Publication number: 20050152660
    Abstract: The illustrative embodiment of the invention is a surface waveguide having low modal birefringence. The surface waveguide has a composite guiding region that is sandwiched by a lower cladding layer and an upper cladding layer, wherein the cladding layers serve to confine propagating light to the composite guiding region. In accordance with the illustrative embodiment, the composite guiding region is structured so that it exhibits a balanced stress configuration, wherein the stress in the direction that aligns with the TE polarization mode is substantially equal to the stress in the direction that aligns with the TM polarization mode. The balanced stress configuration results in a surface waveguide that exhibits very low modal birefringence.
    Type: Application
    Filed: January 13, 2004
    Publication date: July 14, 2005
    Inventors: Rene Heideman, Marcel Hoekman