Abstract: Disclosed are methods, apparatuses, and systems, for (1) providing reliable identification of analytes from an HPLC or other analytical instrument, (2) ensuring data integrity during transfer of analytical data from the instrument to, for example, a control application or other destination, and (3) near-immediate transfer of the data after analysis. Embodiments include methods, apparatuses, and systems that automatically identify a subset of analytes from a plurality of analytes able to be analyzed by a liquid chromatograph (or similar instrument) and that automatically extract a subset of result data from the instrument, where the result data relates to a liquid mixture sample from a reactor (or other source) and where the subset of data corresponds to the subset of analytes. The subset of data may then be used to control a reactor process, or other process, by, for example, transferring the subset of data to a control application.

Abstract: An automatic sterile sampling system for sampling fluid includes a steam valve, a sampling valve, a processing system, an isolation valve, and a controller. The inner diameters of the valve ports and fluid lines are less than about 8 mm. The system has tapered transitions between an outlet port of the sampling valve and an inlet port of the isolation valve and between a sample transfer port of the isolation valve and a sample transfer channel. An isolation valve drain outlet port protrudes upwardly from the isolation valve and has a longitudinal axis that is angled less than about 45° with from vertical.