Patents by Inventor Marcel John De Groot
Marcel John De Groot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20260014147Abstract: The present disclosure relates to a compound according to formula (1): and pharmaceutically acceptable salts, hydrates, or solvates thereof. The disclosure further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.Type: ApplicationFiled: March 26, 2025Publication date: January 15, 2026Inventors: Patrick Stephen Johnson, Geanna Min, Thomas Holmstrøm, Sebastian Clementson, Pablo Martín-Gago, Kristoffer Månsson, Morten Jørgensen, Kevin Neil Dack, Marcel John de Groot
-
Publication number: 20260001893Abstract: Novel modulators of STAT6 having the general formula (I) or a pharmaceutically acceptable salt or stereoisomer thereof, and their use in therapy, and pharmaceutical compositions comprising said compounds.Type: ApplicationFiled: March 26, 2025Publication date: January 1, 2026Inventors: Pablo Martín-Gago, Nadia Nasser Petersen, Bjarne Nørremark, Sebastian Clementson, Morten Dahl Sørensen, Shaoquan Lin, Kevin Neil Dack, Morten Jørgensen, Marcel John de Groot, Mia Noerreskov Burhardt
-
Publication number: 20250340551Abstract: The present disclosure relates to a compound according to formula (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The disclosure further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.Type: ApplicationFiled: March 26, 2025Publication date: November 6, 2025Inventors: Pablo Martín-Gago, Nadia Nasser Petersen, Bjarne Nørremark, Sebastian Clementson, Morten Dahl Sørensen, Shaoquan Lin, Kevin Neil Dack, Morten Jørgensen, Marcel John de Groot, Mia Noerreskov Burhardt
-
Publication number: 20250325677Abstract: The present disclosure provides a compound according to formula (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The disclosure further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.Type: ApplicationFiled: March 26, 2025Publication date: October 23, 2025Inventors: Patrick Stephen Johnson, Geanna Min, Thomas Holmstrøm, Sebastian Clementson, Pablo Martín-Gago, Kristoffer Månsson, Morten Jørgensen, Kevin Neil Dack, Marcel John de Groot, Mark David Andrews
-
Publication number: 20250320205Abstract: The present disclosure relates to a compound according to formula (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The disclosure further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.Type: ApplicationFiled: March 26, 2025Publication date: October 16, 2025Inventors: Patrick Stephen Johnson, Geanna Min, Thomas Holmstrøm, Sebastian Clementson, Pablo Martín-Gago, Kristoffer Månsson, Morten Jørgensen, Kevin Neil Dack, Marcel John de Groot
-
Publication number: 20250320206Abstract: The present disclosure provides a compound according to formula (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The disclosure further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.Type: ApplicationFiled: March 26, 2025Publication date: October 16, 2025Inventors: Patrick Stephen Johnson, Geanna Min, Thomas Holmstrøm, Sebastian Clementson, Pablo Martín-Gago, Kristoffer Månsson, Morten Jørgensen, Kevin Neil Dack, Marcel John de Groot, Mark David Andrews
-
Patent number: 8772293Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I): or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: GrantFiled: July 8, 2011Date of Patent: July 8, 2014Assignees: Pfizer Limited, Icagen Inc.Inventors: Alan Daniel Brown, Marcel John De Groot, Brian Edward Marron, David James Rawson, Thomas Ryckmans, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West
-
Patent number: 8685977Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: GrantFiled: July 11, 2011Date of Patent: April 1, 2014Assignee: Pfizer LimitedInventors: Andrew Simon Bell, Alan Daniel Brown, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Marcel John De Groot
-
Patent number: 8592629Abstract: This invention relates to sulfonamide derivative of formula (I), to their use in medicine, to compositions containing them, to processes for their preparation, and to intermediates used in such processes. These compounds are inhibitors of Nav1.7.Type: GrantFiled: July 11, 2011Date of Patent: November 26, 2013Assignee: Pfizer LimitedInventors: Andrew Simon Bell, Alan Daniel Brown, Marcel John De Groot, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Nigel Alan Swain, Steven Matthieu Gaulier
-
Publication number: 20120010183Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Het1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: ApplicationFiled: July 11, 2011Publication date: January 12, 2012Applicant: PFIZER LIMITEDInventors: Andrew Simon Bell, Alan Daniel Brown, Marcel John De Groot, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Nigel Alan Swain, Steven Matthieu Gaulier
-
Publication number: 20120010207Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: ApplicationFiled: July 11, 2011Publication date: January 12, 2012Applicant: PFIZER LIMITEDInventors: Andrew Simon Bell, Alan Daniel Brown, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Marcel John De Groot
-
Publication number: 20120010182Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I): or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: ApplicationFiled: July 8, 2011Publication date: January 12, 2012Applicants: ICAGEN INC., PFIZER LIMITEDInventors: Alan Daniel Brown, Marcel John De Groot, Brian Edward Marron, David James Rawson, Thomas Ryckmans, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West
