Patents by Inventor Marcel K. Eberle

Marcel K. Eberle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 0-hydroxyethyl and acyloxyethyl derivatives of [ser].sup.8 cyclosporins
    Patent number: 5284826
    Abstract: Hydroxy-substituted [(D)Ser].sup.8 -Ciclosporin derivatives, particularly [O-(2-hydroxyethyl)(D)Ser].sup.8 -Ciclosporin, have advantageous pharmacological properties and are useful as immunosuppressants, for example in the treatment of transplant rejection and autoimmune diseases.
    Type: Grant
    Filed: August 27, 1992
    Date of Patent: February 8, 1994
    Assignee: Sandoz Ltd.
    Inventor: Marcel K. Eberle
  • 2-Amino-5-(trifluoromethylphenylalkyl)-1,3,4 thiadiazoles used in the treatment of insomnia and anxiety
    Patent number: 4054665
    Abstract: 2-amino-5-(substituted or unsubstituted phenylalkyl)-1,3,4-thiadiazoles, e.g., 2-amino-5-(3-trifluoromethylbenzyl)-1,3,4-thiadiazole, prepared, e.g., by ring closure, of corresponding 1-(substituted or unsubstituted phenylalkanoyl)-thiosemicarbazide in a strong acid medium. The compounds are useful as minor tranquilizers and sleep inducers.
    Type: Grant
    Filed: March 10, 1976
    Date of Patent: October 18, 1977
    Assignee: Sandoz, Inc.
    Inventors: Marcel K. Eberle, Robert E. Manning
  • 1-Dioxolanylpropyl-3-indoleacrylic acid esters
    Patent number: 3997670
    Abstract: 1-dioxolanylpropyl-3-indoleacrylic acid esters, e.g., 1-[3-(2-methyl-2-dioxolanyl)propyl]-3-indoleacrylic acid ethyl ester, are prepared by reacting a corresponding 1-dioxolanylpropyl-3-indolecarboxaldehyde with carbalkoxymethylene triphenylphosphorane and are useful as hypolipidemic agents.
    Type: Grant
    Filed: February 6, 1975
    Date of Patent: December 14, 1976
    Assignee: Sandoz, Inc.
    Inventor: Marcel K. Eberle
  • 2-Amino-5-(substituted or unsubstituted phenylalkyl)-thiadiazoles
    Patent number: 3992396
    Abstract: 2-amino-5-(substituted or unsubstituted phenylalkyl)-thiadiazoles, e.g., 2-amino-5-(4-[phenylbutyl])-thiadiazole, prepared, e.g., by ring closure, of corresponding 1-(substituted or unsubstituted phenylalkanoyl)-thiosemicarbazide in a strong acid medium. The compounds are useful as minor tranquilizers and sedative hypnotics.
    Type: Grant
    Filed: November 29, 1974
    Date of Patent: November 16, 1976
    Assignee: Sandoz, Inc.
    Inventors: Marcel K. Eberle, Robert E. Manning
  • 2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles
    Patent number: 3965110
    Abstract: 2-amino-5-(substituted or unsubstituted phenylalkyl)-1,3,4-thiadiazoles, e.g., 2-amino-5-(3-trifluoromethylbenzyl)-1,3,4-thiadiazole, prepared, e.g., by ring closure, of corresponding 1-(substituted or unsubstituted phenylalkanoyl)-thio-semicarbazide in a strong acid medium. The compounds are useful as minor tranquilizers and sleep inducers.
    Type: Grant
    Filed: November 29, 1974
    Date of Patent: June 22, 1976
    Assignee: Sandoz, Inc.
    Inventors: Marcel K. Eberle, Robert E. Manning