Abstract: Disclosed herein are a retrofit device adapted to upgrade bioreactor systems that require at least partially manual addition of liquids, and a method for using the retrofit device with the bioreactor systems. The retrofit device automatically adds the liquids by weight to the bioreactor vessels according to a protocol or procedure. The retrofit device also includes a valve that in the event of power cut-off automatically closes to prevent unintentional addition of liquids.

Abstract: The disclosure provides a method of reducing aggregates in a preparation of monoclonal antibody by modifying at least three parameters in the bioreactor culture process.

Abstract: A xerographic cassette for a printing or copying machine includes a photoreceptor drum, a cleaning blade, and a waste toner conveyor for conveying waste toner cleaned off the photoreceptor drum by the cleaning blade into the interior of the photoreceptor drum for storage. The conveyor includes a flexible helical wire which acts as an auger. A curved tube portion of the conveyor passes through an auxiliary waste toner container. Once the auxiliary container is substantially full, waste toner is conveyed into the interior of the photoreceptor drum. The auxiliary container is provided with an aperture which enables it to be emptied, thereby prolonging the useful life of the cassette.