Patents by Inventor Marcel Leutenegger
Marcel Leutenegger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210397014Abstract: An optical module for imaging light emitting objects on an image sensor comprises a polarizing beam splitter having an entrance face, an exit face, first and a second return faces, a first reflector facing the first return face, a first achromatic quarter-wave retardation plate between the first return face and the first reflector, a second reflector facing the second return face, and a second achromatic quarter-wave retardation plate between the second return face and the second reflector. The first and second reflectors differ in at least one of their orientation with regard to the first and second return faces or their spectral properties. At least one of the first reflector and the second reflector comprises a dichroic mirror arranged between the respective achromatic quarter-wave retardation plate and a further mirror of the respective reflector. The dichroic mirror is tilted with regard to the further mirror of the respective reflector.Type: ApplicationFiled: August 4, 2021Publication date: December 23, 2021Inventors: Marcel Leutenegger, Wim Vandenberg, Peter Dedecker, Arno Bouwens
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Patent number: 10617303Abstract: A functional optical coherent imaging (fOCI) platform includes at least one active camera unit (ACU) having a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOD.Type: GrantFiled: July 28, 2017Date of Patent: April 14, 2020Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Theo Lasser, Dimitri Van De Ville, Erica Martin-Williams, Marcel Leutenegger, Iwan Maerki, Michael Friedrich, Martin Villiger
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Publication number: 20180098702Abstract: A functional optical coherent imaging (fOCI) platform includes at least one active camera unit (ACU) having a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit. SAU); and an operator interface (HOD.Type: ApplicationFiled: July 28, 2017Publication date: April 12, 2018Inventors: Theo LASSER, Dimitri VAN DE VILLE, Erica MARTIN-WILLIAMS, Marcel LEUTENEGGER, Iwan MAERKI, Michael FRIEDRICH, Martin VILLIGER
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Patent number: 9757039Abstract: A functional optical coherent imaging (fOCI) platform includes at least one active camera unit (ACU) having a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOD.Type: GrantFiled: June 29, 2015Date of Patent: September 12, 2017Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Theo Lasser, Dimitri Van De Ville, Erica Martin-Williams, Marcel Leutenegger, Iwan Maerki, Michael Friedrich, Martin Villiger
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Patent number: 9658442Abstract: The invention describes a method and a microscopy system for imaging and analyzing stochastically and independently blinking point-like emitters. A multiple-order cumulants analysis in conjunction with an established blinking model enables the extraction of super-resolved environment-related parameter maps, such as molecular state lifetimes, concentration and brightness distributions of the emitter. In addition, such parameter maps can be used to compensate for the non-linear brightness and blinking response of higher-order cumulant images—used for example in Super-resolution Optical Fluctuation Imaging (SOFI)—to generate a balanced image contrast. Structures that otherwise would be masked by brighter regions in the conventional cumulant image become samples using spectral cross-cumulants.Type: GrantFiled: March 31, 2012Date of Patent: May 23, 2017Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Stefan Geissbuehler, Claudio Dellagiacoma, Matthias Geissbuehler, Theo Lasser, Marcel Leutenegger
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Publication number: 20160367145Abstract: A functional optical coherent imaging (fOCI) platform includes at least one active camera unit (ACU) having a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOD.Type: ApplicationFiled: June 29, 2015Publication date: December 22, 2016Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Theo LASSER, Dimitri VAN DE VILLE, Erica MARTIN-WILLIAMS, Marcel LEUTENEGGER, Iwan MAERKI, Michael FRIEDRICH, Martin VILLIGER
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Patent number: 9066686Abstract: The present invention relates to a functional optical coherent imaging (fOCI) platform comprising at least one active camera unit (ACU) comprising a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOD.Type: GrantFiled: July 10, 2008Date of Patent: June 30, 2015Assignee: Novadaq Technologies Inc.Inventors: Theo Lasser, Dimitri Van De Ville, Erica Martin-Williams, Marcel Leutenegger, Iwan Maerki, Michael Friedrich, Martin Villiger
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Patent number: 8929974Abstract: In a system and a method for examining an object containing a fluid liquid, the object is illuminated with measuring light and images are temporarily shortly subsequently recorded. The images are evaluated per pixel to determine perfusion data from a high frequency portion above 1 kHz and to determine further information about properties of the object from a low frequency portion below 100 Hz, such as a degree of oxygenation of hemoglobin, a concentration of hemoglobin or a concentration of ICG. This information determined by evaluation is displayed in a form of an image in superposition with a white light image of the object.Type: GrantFiled: April 8, 2010Date of Patent: January 6, 2015Assignee: Carl Zeiss Meditec AGInventors: Christoph Hauger, Werner Nahm, Theo Lasser, Marcel Leutenegger, Erica Martin-Williams, Antonio Lopez
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Publication number: 20140198198Abstract: The invention describes a method and a microscopy system for imaging and analysing stochastically and independently blinking point-like emitters. A multiple-order cumulants analysis in conjunction with an established blinking model enables the extraction of super-resolved environment-related parameter maps, such as molecular state lifetimes, concentration and brightness distributions of the emitter. In addition, such parameter maps can be used to compensate for the non-linear brightness and blinking response of higher-order cumulant images—used for example in Super-resolution Optical Fluctuation Imaging (SOFI)—to generate a balanced image contrast. Structures that otherwise would be masked by brighter regions in the conventional cumulant image become samples using spectral cross-cumulants.Type: ApplicationFiled: March 31, 2012Publication date: July 17, 2014Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Stefan Geissbuehler, Claudio Dellagiacoma, Matthias Geissbuehler, Theo Lasser, Marcel Leutenegger
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Publication number: 20110169978Abstract: The present invention relates to a functional optical coherent imaging (fOCI) platform comprising at least one active camera unit (ACU) comprising a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOD.Type: ApplicationFiled: July 10, 2008Publication date: July 14, 2011Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Theo Lasser, Dimitri Van De Ville, Erica Martin-Williams, Marcel Leutenegger, Iwan Maerki, Michael Friedrich, Martin Villiger
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Publication number: 20110090325Abstract: In a system and a method for examining an object containing a fluid liquid, the object is illuminated with measuring light and images are temporarily shortly subsequently recorded. The images are evaluated per pixel to determine perfusion data from a high frequency portion above 1 kHz and to determine further information about properties of the object from a low frequency portion below 100 Hz, such as a degree of oxygenation of hemoglobin, a concentration of hemoglobin or a concentration of ICG. This information determined by evaluation is displayed in a form of an image in superposition with a white light image of the object.Type: ApplicationFiled: April 8, 2010Publication date: April 21, 2011Applicant: Carl Zeiss Surgical GmbHInventors: Christoph Hauger, Werner Nahm, Theo Lasser, Marcel Leutenegger, Erica Martin-Williams, Antonio Lopez
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Publication number: 20100130869Abstract: A method and an apparatus for displaying a part of a brain of a patient is provided. Laser Doppler images are acquired before and after a stimulation. The laser Doppler images comprise information about a blood motion or about a perfusion at the acquired part. Then, the blood motion images acquired before and after the stimulation are compared to identify areas in the brain of the patient which are related to the stimulation. The identified areas are displayed in dependence of topography data representing a topography of the brain.Type: ApplicationFiled: October 14, 2009Publication date: May 27, 2010Applicant: Carl Zeiss Surgical GmbHInventors: Christoph Hauger, Werner Nahm, Theo Lasser, Marcel Leutenegger, Erica Martin-Williams, Antonio Lopez