Patents by Inventor Marcel Mersel

Marcel Mersel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions containing beta-2 microglobulin and methods of treating autoimmune diseases
    Patent number: 11484571
    Abstract: A pharmaceutical product containing ?2-microglobulin or a functional variant thereof as an active ingredient in the form of liposomes is provided. The product can increase the concentration of ?2-microglobulin in the blood, and can also restore a normal HC/?2-microglobulin molar ratio within membrane MHC-I complexes, or prevent a ?2-microglobulin deficit from occurring in the MHC-I complexes, of patients suffering from autoimmune diseases. Methods of treating patients with the pharmaceutical product are also presented.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: November 1, 2022
    Assignee: BETA INNOV
    Inventors: Marcel Mersel, Clovis Rakotoarivelo
  • COMPOSITION CONTAINING A 7BETA-HYDROXYCHOLESTEROL AND A LIPID VEHICLE, AND ITS USE IN THE TREATMENT OF NEOPLASTIC PATHOLOGIES
    Publication number: 20210283146
    Abstract: Disclosed is a composition including a 7?-hydroxycholesterol derivative and a lipid vehicle, in particular a vegetable oil, and use thereof in the treatment of neoplastic pathologies, such as glioblastoma multiforme. The composition may be administered by the oral route.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 16, 2021
    Inventors: Marcel MERSEL, Clovis RAKOTOARIVELO
  • Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies
    Patent number: 10800806
    Abstract: Novel sterol derivatives, the preparation method thereof, pharmaceutical compositions containing them and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies. The treatment of glioblastoma multiforme, as well as of other cancers, such as lymphomas, neuroblastomas and melanomas is also described.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: October 13, 2020
    Assignee: BETA INNOV
    Inventors: Ludovic Clarion, Marcel Mersel, Didier Petite
  • PHARMACEUTICAL COMPOSITIONS CONTAINING BETA-2 MICROGLOBULIN AND METHODS OF TREATING AUTOIMMUNE DISEASES
    Publication number: 20170035846
    Abstract: A pharmaceutical product containing ?2-microglobulin or a functional variant thereof as an active ingredient in the form of liposomes is provided. The product can increase the concentration of ?2-microglobulin in the blood, and can also restore a normal HC/?2-microglobulin molar ratio within membrane MHC-I complexes, or prevent a ?2-microglobulin deficit from occurring in the MHC-I complexes, of patients suffering from autoimmune diseases. Methods of treating patients with the pharmaceutical product are also presented.
    Type: Application
    Filed: October 20, 2016
    Publication date: February 9, 2017
    Inventors: Marcel MERSEL, Clovis RAKOTOARIVELO
  • STEROL DERIVATIVES AND USE THEREOF FOR TREATING DISEASES INVOLVING TRANSFORMED ASTROCYTE CELLS OR FOR TREATING MALIGNANT HAEMOPATHIES
    Publication number: 20150086615
    Abstract: Novel sterol derivatives, the preparation method thereof, pharmaceutical compositions containing them and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies. The treatment of glioblastoma multiforme, as well as of other cancers, such as lymphomas, neuroblastomas and melanomas is also described.
    Type: Application
    Filed: May 7, 2013
    Publication date: March 26, 2015
    Applicant: BETA INNOV
    Inventors: Ludovic Clarion, Marcel Mersel, Didier Petite
  • Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same
    Patent number: 8383609
    Abstract: A new anticancer compounds of formula (1) Drugs and pharmaceutical compositions to be used in human or veterinary medicine, which include at least one compound of formula (1).
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: February 26, 2013
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Jean-Luc Pirat, David Virieux, Ludovic Clarion, Jean-Noël Volle, Norbert Bakalara, Marcel Mersel, Jerôme Montbrun, Henri-Jean Cristau
  • THERAPEUTIC USE OF THE ß2m PROTEIN
    Publication number: 20130017212
    Abstract: The use of beta2-microglobulin (?2m) as active ingredient, in particular in pharmaceutical compositions intended for the treatment of autoimmune diseases.
    Type: Application
    Filed: April 6, 2011
    Publication date: January 17, 2013
    Applicant: BETA INNOV
    Inventors: Marcel Mersel, Clovis Rakotoarivelo
  • PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME
    Publication number: 20100298272
    Abstract: A new anticancer compounds of formula (1) Drugs and pharmaceutical compositions to be used in human or veterinary medicine, which include at least one compound of formula (1).
    Type: Application
    Filed: July 7, 2008
    Publication date: November 25, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Luc Pirat, David Virieux, Ludovic Clarion, Jean-Noel Volle, Norbert Bakalara, Marcel Mersel, Jerome Montbrun, Henri-Jean Cristau
  • PROCESS FOR THE HYDROXYLATION OF AN ACYCLIC OR CYCLIC METHYLENE RADICAL IN THE ALLYLIC POSITION, PHARMACEUTICAL COMPOSITION CONTAINING HYDROXYCHOLESTEROL DERIVATIVES AND UTILIZATION OF SUCH COMPOSITIONS FOR THE PREPARATION OF DRUGS
    Patent number: 6423702
    Abstract: A pharmaceutical composition conatining at least one C3-OH ether or fatty acid monoester of 7B-hydroxycholesterol selected from the group consisting of the ethers or esters of palmitic, oleic, hexenoic, decenoic and arachindonic acids or esters. The composition is useful as a cytotoxic agent for the treatment on cells having a high proliferative potential.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: July 23, 2002
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: Patrick Behr, Alexandre Kupferberg, Marcel Mersel, Alain Privat